Clinical trials: Hand Functions
Stroke
Sensory Stimulation to Enhance Hand Function Post Stroke
The objective of this pilot project is to assess the impact of the novel sensory stimulation technique the investigators have developed in enhancing outcomes of hand therapy as well as the central nervous system responsiveness in…
- Trial name
- NCT02675764
- Testing
- Vibration, therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to compare two different treatments -- Contralataterally Controlled Functional Electrical Stimulation (CCFES)…
- Conditions
- Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00891319
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- MetroHealth Medical Center
Paresis, Stroke
FAME: Functional Assessment of a Myoelectric Orthosis Hand Orthoses
The primary study objective is to compare post-stroke upper extremity (UE) movement while wearing a brace called the MyoPro 2 Motion G versus UE movement while wearing a resting splint and no device in stroke survivors with…
- Trial name
- FAME (NCT04266158)
- Testing
- Myoelectric UE Device-UE Orthosis-No Device
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University
Cerebral Palsy
Contralaterally Controlled FES for Hand Opening in Hemiplegic Cerebral Palsy
This is a pilot randomized controlled trial of an intervention to improve arm function in children ages 6 to 17 with cerebral palsy and upper limb hemiparesis.
- Trial name
- NCT02925455
- Testing
- Contralaterally-controlled functional electrical stimulation, Hand therapy video games
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injury
Improving Motor Function After Spinal Cord Injury
The goals of this study are to examine the physiology of Central Nervous System pathways contributing to the control of upper and lower extremity movements after SCI, and to promote the recovery of extremity movements by using…
- Trial name
- NCT01915095
- Testing
- rTMS, Training, Motor Task
- Where
- 3 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Improving Holding Function of the Hemiplegic Hand
Relevant to patients with spastic hemiparesis in the hand and upper limb, this pilot project proposes to measure the effects of botulinum toxin injections through observation of performance on a functional task known as 'hand as…
- Trial name
- NCT02459951
- Testing
- clenched fist
- Volunteers
- 10 people
- Sponsor
- Nathaniel Mayer
Brain Infarction, Brain Ischemia
Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm
Overall goal of this study is to determine if transcranial direct current stimulation (tDCS) plus conventional occupational therapy improves functional motor recovery in the affected arm-hand in patients after an acute ischemic…
- Trial name
- NCT01201629
- Testing
- t DC stimulation, tDCStimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Spinal Cord Injuries
Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI
The purpose of this study is to test the efficacy of mild breathing bouts of low oxygen (intermittent hypoxia) combined with transcutaneous electrical spinal cord stimulation on restoring hand function in persons with chronic…
- Trial name
- NCT04854057
- Testing
- AIH - Intermittent Hypoxia - hypoxia air mixture, TESS - Transcutaneous Electrical Spinal Cord Stimulation + Functional Task Practice
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke
Combined Brain and Peripheral Nerve Stimulation for Stroke
Cerebrovascular disease is a major cause of disability worldwide. The catastrophic burden of stroke is more dramatic in low- and middle- income countries, and the scarcity of evidence-based rehabilitation interventions represents…
- Trial name
- NCT01907737
- Testing
- Active tDCS, Active PNS
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Stroke
Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke (795,000/year in the US and 30 million existing stroke survivors in the world) damages brain neural structures that control coordinated upper limb movement.
- Trial name
- NCT02856035
- Testing
- Neural feedback plus FES and motor training
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Scleroderma, Systemic Sclerosis
Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility Study
The Scleroderma Patient-centered Intervention Network (SPIN) is an organization established by researchers, health care providers, and people living with scleroderma from Canada, the USA, and Europe.
- Trial name
- SPIN-HAND-F (NCT03092024)
- Testing
- SPIN-HAND program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Lady Davis Institute
Stroke, Upper Extremity Paresis
Synchronized Brain and Hand Stimulation After Stroke
Among the 795,000 individuals who sustain a stroke annually in the United States, 65% continue to experience moderate-to-severe impairments in one hand six months or more, which limits their ability to perform daily tasks.
- Trial name
- NCT04502290
- Testing
- Combined Non-invasive brain stimulation and functional electrical hand stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Amit Sethi
Cerebral Palsy
Sensory Stimulation During CIMT
The long-term goal of this project is to assess the impact of the novel sensory stimulation technique in enhancing outcomes of constraint-induced movement therapy (CIMT) in children with cerebral palsy. This is a pilot project.
- Trial name
- NCT03558230
- Testing
- Standardized Constraint-Induced Movement Therapy, Vibration
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medical University of South Carolina
Injury of Extensor Tendon of Hand, Tendon Adhesions
Evaluation of High-Purity Type I Collagen Biologic Wrap to Improve Function After Extensor Tendon Repair of the Hand
Tendon injuries of the hand, particularly extensor tendons, are prone to postoperative adhesions, extensor lag, and stiffness, leading to functional impairment.
- Trial name
- NCT07335653
- Testing
- High-Purity Type I Collagen (HPTC) Wrap, Standard Extensor Tendon Repair
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Stroke, Brain Diseases
Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke
The goal of this study is to verify whether electrical stimulation of the cervical spinal cord can activate muscles of the arm and hand in people with hemiplegia following stroke.
- Conditions
- Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- NCT04512690
- Testing
- Epidural electrical stimulation (EES) of the cervical spinal cord
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Lee Fisher, PhD
Hand Function, Stroke
TheraBracelet Phase I
This project aims to test a new technology that may improve hand function impaired from a stroke, thereby improving independence and quality of life.
- Conditions
- Hand Function, Stroke, Upper Extremity, Hemiparesis
- Trial name
- NCT03318341
- Testing
- Real Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- TheraBracelet, Inc.
Stroke, Impaired Upper Extremity Function
Extension of the MIME Robotic System for Stroke Rehabilitation
The goal of this project is to develop and test a new robotic system to accommodate practice of tasks requiring reach, grasp and release of objects.
- Trial name
- NCT00995774
- Testing
- robotic therapy, conventional functional training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- US Department of Veterans Affairs
Cerebral Palsy Spastic Hemiplegic
Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
This study evaluates the therapeutic effects of constraint-induced movement therapy on infants and children with hemiplegic cerebral palsy.
- Trial name
- NCT03858335
- Testing
- Constraint-induced movement therapy
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Stroke
Functional Connectivity & Stimulation-enhanced Therapy Post Stroke
After stroke, it is common for individuals to experience hand impairment. This deficit can severely restrict functional ability and independence. Recovery of hand function following stroke is highly variable.
- Trial name
- NCT03473808
- Testing
- task-practice therapy, Vibration
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina