Clinical trials: Halitosis
Halitosis
Effects of Mechanical, Chemical, and Combination Methods on Halitosis
Goal: The goal of this clinical trial is to evaluate the effectiveness of different oral hygiene methods (tooth brushing, tongue cleaning, and mouthwash use) in managing halitosis (bad breath) in adults.
- Trial name
- NCT06890104
- Testing
- Mouthrinse with Coconut oil pulling, Mouthrinse with Chlorhexidine 0.12%
- Where
- Vietnam
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Halitosis
Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of Halitosis
Halitosis is a term that defines any odor or bad smell coming from the oral cavity, which can have a local or systemic origin. This project aims to verify if there is a difference in the effectiveness of treatment with…
- Trial name
- NCT06583720
- Testing
- Oral hygiene at home, aPDT, Probiotics
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Nove de Julho
Halitosis
Oral Hygiene Procedures on Reduction of Oral Malodor
The purpose of the study is to evaluate the effect of various oral hygiene procedures on reduction of oral malodor.
- Trial name
- NCT02113137
- Testing
- group 1: drug: chlorine dioxide, group 2: device: small tooth brush for tongue cleaning
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ei Ei Aung
Halitosis
Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral Halitosis
Purpose: To investigate the short-term clinical effect of curcumin-containing toothpaste on halitosis as compared to placebo and to assess potential shifts in the composition of dental biofilm associated with the use of…
- Trial name
- NCT04998617
- Testing
- Toothpaste with curcumin, Toothpaste without curcumin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Halitosis
Laser Tongue Debridement for Oral Malodor
Malodor is a multifactorial condition with oral pathology representing the main culprit and the tongue being the first to second contributor to the malodor.
- Trial name
- NCT04120948
- Testing
- Waterlase Express Laser System, Tongue scraper
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Gastrointestinal Symptoms, Bloating
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
This is a decentralized (fully virtual), single-group, open-label, prospective clinical trial evaluating the effects of Super Liver Liquid Drops, a liquid botanical dietary supplement, on gut health, digestive comfort, energy…
- Conditions
- Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
- Trial name
- NCT07742657
- Testing
- Super Liver
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SuperBonsai Inc.
Periodontitis, Halitosis
The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy
Periodontitis can lead to tooth loss which may impair chewing ability and aesthetics. In addition, periodontitis can give rise to halitosis.
- Conditions
- Periodontitis, Halitosis, Tongue Condition
- Trial name
- NCT06091228
- Testing
- tongue scraper
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Halitosis
A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis
The purpose of this study is to investigate the efficacy of an experimental dentifrice, containing 0.454 percent (%) stannous fluoride and 0.3% zinc chloride, to reduce oral malodor, compared to a marketed regular fluoride…
- Trial name
- NCT05524948
- Testing
- Experimental Dentifrice, Reference Dentifrice
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- HALEON
Bad Breath, Tooth Sensitivity
A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort
This is a single-group, open-label, decentralized (virtual) clinical trial evaluating the effects of Larineco Remineralizing Gum on self-reported oral health outcomes in 40 generally healthy adults aged 18-57 years who experience…
- Trial name
- NCT07692581
- Testing
- Larineco Remineralizing Gum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Larine C Corporation
Halitosis, Oral Malodor
Prevention of Oral Malodor With an Oral Sticker Containing Herbal Formula
the use of a herbal formulation containing sage, echinacea,lavender and mastic gum would prevent oral malodor if delivered in an appropriate delivery system to enable slow release of the active ingredients.
- Conditions
- Halitosis, Oral Malodor, Bad Breath
- Trial name
- NCT00250289
- Testing
- a mucosal sticker with herbal formula
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Halitosis
A New Portable Monitor for Measuring Odorous Compounds in Oral, Exhaled and Nasal Air
The B/B Checker, a new portable device for detecting odorous compounds in oral, exhaled, and nasal air, is now available. As a single unit, this device is capable of assessing several kinds of gases mixed with volatile sulfur…
- Trial name
- NCT01139073
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Okayama University
Oral Malodor (Halitosis)
Effect of Toothpastes on Oral Malodor
This study aimed to evaluate the effects of different toothpaste formulations on oral malodor in young adults, addressing the lack of clinical evidence regarding propolis- and probiotic-containing toothpastes, which have…
- Trial name
- NCT07329062
- Testing
- Propolis Containing Toothpaste, Probiotic containing toothpaste, Phosphate-based formulation toothpaste
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Periodontitis, Halitosis
Adjunctive Effect of Photodynamic Therapy on Halitosis
The present study aims to evaluate bad breath in patients undergoing gingival treatment combined with tongue scraping and laser and to assess its potential benefits for both periodontal and microbiological condition.
- Trial name
- NCT06764342
- Testing
- Full-mouth scaling combined with antimicrobial photodynamic therapy, full-mouth scaling
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Oral Malodor (Halitosis), Oral Dryness
Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults
The goal of this clinical trial is to compare a toothpaste designed for adults aged 50 years and older with a standard toothpaste in orally healthy adults.
- Trial name
- HALI-50PLUS (NCT07780474)
- Testing
- 50+ Toothpaste, Standard Fluoride Toothpaste
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dry Mouth, Halitosis
Questionnaire Regarding the Effect of Wearing Face Masks on Oral Health
During the current COVID-19 pandemic, the use of face masks is recommended / mandatory to prevent infection. Patients and students have reported to experience limitations in their oral health-related quality of life, especially…
- Trial name
- NCT04632004
- Testing
- Invitation to participate
- Where
- Germany
- Volunteers
- 3,750 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Oral Malodor, Halitosis
Effect of Miswak and Miswak Extract on Oral Malodor
The aim of this experiment is to investigate the effect of Miswak on oral malodor and to determine whether this effect -if present- is the result of the mechanical action of Miswak or the chemical effect of its extract
- Trial name
- NCT02628938
- Testing
- Miswak extract mouth wash, Miswak stick, Chlorohexidine gluconate
- Where
- Saudi Arabia
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Nutritional and Metabolic Diseases
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
The purpose of this study is to identify metabolic signatures associated with malodor conditions. The investigators will perform state-of-the art metabolomics tests and bioinformatic data mining to explore if conditions leading…
- Trial name
- NCT02683876
- Where
- 2 sites in United States, Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mebo Research, Inc.
Halitosis
Green Tea With Aloe Vera Mouthwash and Chlorohexidine Mouthwash
The Effect of Mouthwash Containing Green Tea With Aloe Vera and Chlorhexidine Mouthwash on Oral Malodour Among a Group of Egyptian Children: Randomized Clinical Trial
- Trial name
- RCT (NCT03115892)
- Testing
- Green Tea With Aloe Vera mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cairo University
Halitosis
Halitosis Devised Questionnaire Evaluating a New Treatment
The investigators propose a novel assessment of oral malodor (halitosis) by a quality of life (QOL) questionnaire designed specifically for halitosis and a new treatment for halitosis by improvement of mouth dryness.
- Trial name
- NCT01046812
- Testing
- Caphosol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York Head & Neck Institute
Halitosis
The Efficacy of Oregano Essential Oil in Reducing Oral Halitosis
the efficacy of commercially available oregano essential oil mouthwash in the reduction of oral halitosis was compared to chlorhexidine and distilled water and the results showed significant reduction of organoleptic tongue and…
- Trial name
- NCT04779502
- Testing
- oregawash, corsodyl
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MOHAMED SAEED M. ALI