Clinical trials: Halitosis
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Halitosis, Orthodontic Appliance Complication
Chios Mastic Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
Halitosis is the third most common oral condition perceived by the patients as pathologic, after caries and periodontal diseases.
- Trial name
- NCT05647369
- Testing
- Mastic mouthwash
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Iosif Sifakakis
Oral Malodor (Halitosis)
Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor
This single-center, randomized, double-blind, two-treatment crossover clinical study evaluated the safety and efficacy of a stannous fluoride-containing dentifrice compared with a sodium fluoride control dentifrice for the…
- Trial name
- NCT07425509
- Testing
- Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Healthy, Periodontitis
Oral and Gut Microbiota Changes During Long-term Fasting in Humans
The aim of this longitudinal trial is to investigate the effects of a 10±3-day fasting period in 30 subjects. Changes in the oral and gut microbiota, halitosis, as well as inflammatory and antioxidative parameters and biomarkers…
- Trial name
- OralFast (NCT05449249)
- Testing
- Long-term fasting
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Halitosis
A Clinical Trial to Assess the Effects of a Mouthwash Containing Chlorine Dioxide on Oral Malodor
A mouthwash containing chlorine dioxide would be effective to reduce oral malodor.
- Trial name
- NCT00655772
- Testing
- Chlorine Dioxide
- Where
- Japan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Periodontitis, Olfactory Dysfunction
Olfactory Function and Oral Malodor in Periodontitis Before and After Periodontal Therapy
This prospective cohort study investigated the relationship between oral malodor and olfactory function in adults with generalized periodontitis.
- Conditions
- Periodontitis, Olfactory Dysfunction, Halitosis
- Trial name
- NCT07424300
- Testing
- Scaling and Root Planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Batman University
Halitosis
Assessing the Effect of Periodontal Debridement, Tongue Cleaning and Mouth Rinsing for the Treatment of Oral Malodour
This study evaluates the short and long term effect of dental cleaning and mouthrinsing for the treatment of bad breath
- Trial name
- NCT02665780
- Testing
- Periodontal debridement, Cetylpyridium chloride
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Halitosis
Evaluation of the Treatment of Halitosis With Photodynamic Therapy in Older Patients With Complete Denture
Halitosis is the term used to define an unpleasant odor emanating from the mouth. Some lung diseases and diabetes are among the extra-oral causes of this condition.
- Trial name
- NCT03960983
- Testing
- Treatment with tongue scraper, Hygiene procedures for the mucosa and dentures, Photodynamic Therapy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Halitosis
Assessment of Photodynamic Therapy With Annatto and Led for the Treatment of Halitosis in Mouth-Breathing Children
Objective: To assess the effectiveness of antimicrobial photodynamic therapy (aPDT) employing an annatto-based (20%) dye combined with blue LED for the treatment of halitosis in mouth-breathing children.
- Trial name
- NCT05590897
- Testing
- Teeth Brushing, Dental Flossing, Tongue Scraping
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Nove de Julho
Halitosis
Photodynamic Therapy in Adolescents Halitosis
The aim of the proposed controlled clinical trial is to evaluate the effect of photodynamic therapy (PDT) on the formation of volatile sulfur compounds (VSCs) from coated tongue and its action on the severity of halitosis in…
- Trial name
- NCT02007993
- Testing
- PDT, Tongue Scraper
- Where
- Brazil
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Denture Stomatitis, Dentures
Oral Probiotics and Denture Care in Saudi Arabia: Evaluating Knowledge, Practices, and the Future of Innovative Hygiene Solutions
The goal of this observational study is to learn about denture wearers' knowledge, awareness, and self-reported practices regarding denture hygiene and oral probiotics, and to assess whether these are associated with clinical…
- Conditions
- Denture Stomatitis, Dentures, Halitosis, Biofilms
- Trial name
- NCT07475195
- Testing
- This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention.
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Saud University
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Halitosis
Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds
The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.
- Trial name
- NCT02689297
- Testing
- chlorine dioxide, small toothbrush for tongue cleaning
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Bad Breath
Effectiveness of Different Candies Against Bad Breath
This study is to analyze whether the candies can relieve or eliminate bad breath, both subjectively and objectively.
- Trial name
- HALIDROP (NCT04589481)
- Testing
- Intake of 3 different candies against bad breath
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Halitosis, Gingivitis
Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula
In a previous study the prevention of halitosis by the herbal formula and delivery system (SmellX), were established both in vitro and clinicaly. The duration of relief was established as long as 8 hours.
- Trial name
- SmellX (NCT01388023)
- Testing
- herbal formula for fresh breath
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Plaque, Halitosis
Impact of Visual Stimuli on Pediatric Oral Hygiene Performance
In the present study, children aged 7 to 14 will receive verbal and active (hands-on) oral hygiene education. The education will be delivered in three different formats: Education supported with positive visual aids (images of…
- Conditions
- Dental Plaque, Halitosis, Oral Hygiene Education Methods
- Trial name
- NCT07150429
- Testing
- Verbal-Active Oral Hygiene Education with Negative Visual Aids, Verbal-Active Oral Hygiene Education (Control Group), Verbal-Active Oral Hygiene Education with Positive Visual Aids
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Halitoses
Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients
This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.
- Trial name
- NCT07693972
- Testing
- Probiotic (L. brevis CD2 lozenges), Zinc chlorhexidine mouth wash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sara M Almshhadany
Oral Malodor (Halitosis)
Hydrogen Sulfide Production by Oral Microflora
Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria.
- Trial name
- NCT00396539
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Halitosis, Tongue Diseases
Inulin and S. Salivarius Reduce Halitosis
Halitosis associated with tongue coating results from the production of volatile sulfur compounds by bacterial action. The use of prebiotics and probiotics might be useful in treating such condition.
- Trial name
- NCT02794766
- Testing
- Inulin+SS, S salivarius
- Volunteers
- 45 people
- Sponsor
- Universidade de Passo Fundo
Orthodontic Appliance Complication, Halitosis
Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
The aim of this trial was to investigate the effect of Cotinus Coggygria mouthwash on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents…
- Trial name
- NCT07254819
- Testing
- Cotinus Coggygria mouthwash
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Athens