Clinical trials: HPV
Head and Neck Cancer, Anogenital Cancer
Decitabine Treatment in HPV-Induced Anogenital and Head and Neck Cancer Patients After Radiotherapy or as Novel Late Salvage
Open-label, single-center phase I study to evaluate first signs of efficacy and to confirm the safety and tolerability of a decitabine safe-dose treatment in two strata of patients with HPV induced anogenital and head and neck…
- Trial name
- DERANO (NCT04252248)
- Testing
- Dacogen
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- University Hospital Heidelberg
Cervical Cancer, Genital Wart
A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females
This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 4-valent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 18-45…
- Conditions
- Cervical Cancer, Genital Wart, CIN1, CIN2
- Trial name
- NCT05584332
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha)
- Where
- China
- Volunteers
- 3,131 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Human Papilloma Virus, Male
A Pilot Study Comparing the Effectiveness of Campus Intervention to Increase HPV Vaccine Rate Among College Aged Men
This is a study testing what type of message and access influences a young male to get the HPV vaccine. The investigators are conducting a 2 X 2 design These conditions are: Condition 1: Altruistic personal with direct…
- Trial name
- NCT02508701
- Testing
- Message X Onsite/Offsite Vaccination
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cervical Intraepithelial Neoplasia, Human Papillomavirus
Comparisons of the Effects and Clinical Outcomes of CH2 Vaginal Gel Versus Placebo on CIN1
In Taiwan, Pap smear screen has been offered every year for women over 30 years old since 1995. The incidence of cervical invasive cancer decreased from 25/100,000 person in 1995 to 7.0/100,1000 person in 2016.
- Trial name
- NCT06582004
- Testing
- CH2 vaginal gel
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Anal Cancer, Squamous Intraepithelial Lesions
Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis
This study aims to learn more about anal cancer risk in men who have sex with men (MSM) who are using Pre-Exposure Prophylaxis (PrEP) to prevent HIV.
- Conditions
- Anal Cancer, Squamous Intraepithelial Lesions, HSIL, High Grade Squamous Intraepithelial Lesions, LSIL, Low-Grade Squamous Intraepithelial Lesions
- Trial name
- SCOPE (NCT07029152)
- Testing
- Anal smear, Self-administered questionnaire, EQ-5D-5L questionnaire
- Where
- 8 sites in Belgium
- Volunteers
- 296 people
- Sponsor
- Universitair Ziekenhuis Brussel
Middle School and High School Students
Impact of an HPV Primary Prevention Intervention on HPV Vaccination Rates Among Adolescents in the AuRA Region.
Human papillomaviruses (HPV) are very common contagious viruses: approximately 70% of men and women will be infected during their lifetime.
- Trial name
- PIMCOP (NCT07414719)
- Testing
- HPV animation
- Where
- France
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Healthy Volunteers
Immune Memory After Papillomavirus Vaccination
Vaccines for human papillomavirus (HPV) have been available in the United States since 2006. Early studies have shown a high rate of effectiveness of these vaccines, however it is not known how long this protection will last.
- Trial name
- IMAP-1 (NCT01505049)
- Testing
- quadrivalent HPV vaccine
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Emory University
HPV-Related Carcinoma
Effectiveness and B-memory Cell Response to QHPV Vaccine 9-years Post-vaccination Among HIV-infected Boys and Girls
In 2013, the Investigators enrolled a cohort of 180 HIV-1 infected adolescent girls and boys ages 9-14 years and administered three doses of the QHPV vaccine (NCT04711265).
- Trial name
- NCT04920526
- Testing
- Quadrivalent HPV [Type 6, 11, 16 and 18] L1 Virus-Like Particle Vaccine
- Volunteers
- 135 people
- Sponsor
- Kenya Medical Research Institute
Human Papilloma Virus (HPV), Cervical Cancers
Unidos Contra el VPH
The purpose of the Unidos Contra el VPH study is to help find options to screen, or check, for cervical cancer that individuals can do at home to help prevent and detect cervical cancer early.
- Trial name
- Unidos (NCT06825689)
- Testing
- Self-sampling with urine, Self-sampling with swab, In-clinic Pap/HPV co-testing
- Where
- United States
- Volunteers
- 735 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
HPV Infection, Health Behavior
HPV Vaccination Health-promotion Programme on Vaccine Acceptance and Uptake Among Female Adolescents
The MDL-SHPVP will be developed and a clustered randomised controlled trial will be conducted to evaluate the effects of the MDL-SHPVP and to examine whether the effect of the MDL-SHPVP on the rate of HPV vaccine uptake 1 year…
- Conditions
- HPV Infection, Health Behavior, Health Attitude
- Trial name
- NCT04438291
- Testing
- MDL-SHPVP, 30-minute educational video
- Where
- Hong Kong
- Volunteers
- 1,340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HPV Vaccination, Uptake Vaccination
PREVENT Pilot HPV - Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT06738355
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Utah
Oropharyngeal Squamous Cell Carcinoma, HPV-mediated Oropharyngeal Squamous Cell Carcinoma
Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.
The goal of this study is to evaluate if a shorter course of therapy can improve the quality of life in patients receiving radiation therapy after trans-oral robotic surgery.
- Trial name
- RAD RAPTORS (NCT07044635)
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Utah
Carcinoma, HIV Infections
Molecular Biology of Anal Cancer in HIV-Positive Patients
The molecular mechanisms involved in squamous cell carcinoma of the anus (SCCA) are poorly elucidated. HIV-positive and renal transplant patients are at high risk for developing SCCA, indicating that immune suppression plays a…
- Trial name
- NCT00952874
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Cervical Cancer
Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Caribbean immigrants (both Hispanics and Blacks from Haiti) are less likely to be screened for cervical cancer than the general population.
- Trial name
- SUCCESS (NCT02121548)
- Testing
- CHW Outreach and HPV Self-sampling, CHW Outreach
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Miami
Human Papillomavirus-Related Carcinoma
MeFirst: A Tailored Intervention to HPV Vaccine Decision Making
This study will test whether a tailored, online educational intervention increases HPV vaccine uptake and intent among female college students.
- Trial name
- NCT01769560
- Testing
- MeFirst Tailored Intervention
- Where
- United States
- Volunteers
- 661 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cervical Neoplasms, Human Papillomavirus
Longitudinal Clinical Evaluation of the HPV Assay on the BD VIPER LT System With Cervical Specimens
The purpose of the study is to assess the cumulative disease detection of greater than or equal to Cervical intraepithelial neoplasia 2 (CIN2) and greater than or equal to Cervical intraepithelial neoplasia 3 (CIN3) in the…
- Trial name
- NCT02267876
- Testing
- BD HPV Assay on Viper LT, Colposcopy
- Where
- 40 sites in United States, Canada
- Volunteers
- 6,730 people, healthy volunteers welcome
- Sponsor
- Becton, Dickinson and Company
Verruca Viral
Gardasil Versus Cervarix in the Treatment of Warts
Warts are common, benign, epidermal proliferations caused by HPV infecting skin and mucous membranes. Treatment of warts poses a true challenge despite existing variable therapeutic modalities, whether destructive or…
- Trial name
- NCT05383625
- Testing
- Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recombinant Vaccine, Bivalent Human Papilloma Virus Vaccine, Saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Gynecologic Cancer
Telehealth & HPV Self-Collection
This study aims to compare the efficacy and participant experience of telehealth-based, self-collected cervical cancer screening to mail-based, self-collected cervical cancer screening across the adult female screening lifespan.
- Trial name
- NCT05089825
- Testing
- Receive routine instructions, Telehealth-based instructional visit and receive routine instructions
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
HPV-Related Cervical Carcinoma, HPV-Related Malignancy
Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.
This is a multi-center study in patients with recurrent or metastatic HPV16-positive, PD-L1 positive cervical cancer who has progressed during or after treatment with the first-line standard of care (pembrolizumab with…
- Conditions
- HPV-Related Cervical Carcinoma, HPV-Related Malignancy, Cervical Cancer
- Trial name
- NCT06099418
- Testing
- VB10.16, Atezolizumab Injection [Tecentriq]
- Sponsor
- Nykode Therapeutics ASA
Cervix Cancer, HPV-Related Malignancy
Prognostic Value of Conization and Negative HPV After Conization in AIS and Early Stage Cervical Cancer
In women with cervical cancer -Squamous cell carcinoma, Adeno carcinoma, Adeno-squamous carcinoma or AIS we want to examine prospectively: 1.
- Trial name
- NCT06196190
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus