Clinical trials: HIV Prevention Program
HIV
Comparing the PrePex™ Device to Surgical MC for Rapid Scale Up of MC in Resource Limited Setting
The protocol, approved by the Medical Research Council, was issued to assess the safety and efficacy of the non-surgical device for applying it to the national scale up of adult male circumcision in Zimbabwe
- Trial name
- NCT01956370
- Testing
- PrePex™ device for adult male circumcision, Surgical circumcision
- Where
- Zimbabwe
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Child Welfare, Zimbabwe
Mentally Ill Persons, Substance Abuse
HIV Prevention Among Substance Abusing SMI
This study seeks to examine the effectiveness of translating two proven interventions, RESPECT, and the NIDA Community Based Outreach Model, into one program of education, PATH, to be delivered by case managers to their seriously…
- Conditions
- Mentally Ill Persons, Substance Abuse, HIV Infections
- Trial name
- NCT00447720
- Testing
- PATH
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- University of Pennsylvania
HIV Prevention, Latino Men Who Have Sex With Men
PrEP & Soccer: A Program for Pharmacy Chains to Increase PrEP Awareness and Access Among Men
This type 3 Hybrid Effectiveness-Implementation study will evaluate PrEP \& Soccer, a multicomponent and multilevel implementation strategy delivered by a pharmacy chain to increase PrEP knowledge and initial PrEP appointment…
- Conditions
- HIV Prevention, Latino Men Who Have Sex With Men, Pharmacy
- Trial name
- NCT07263048
- Testing
- PrEP & Soccer PrEP Navigation, CVS Health brochure
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Miami
Parent-Child Relations, HIV Prevention
Development and Testing of a Jamaican Mother-daughter HIV Risk-reduction Program
Caribbean nations, including Jamaica, exhibit HIV rates that are second only to sub-Saharan Africa. Jamaican young women and adolescent girls are at particularly high risk due to a number of cultural factors, gender norms…
- Conditions
- Parent-Child Relations, HIV Prevention, Adolescent Behavior
- Trial name
- NCT03411577
- Testing
- Behavioral Intervention
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Boston College
Tobacco Use Cessation
An Evidence Based Smoking Cessation Program for Persons Living With HIV/AIDS (Project Legacy)
The goal of this research study is to compare 2 different phone-based programs for quitting smoking for people with HIV/AIDS.
- Trial name
- NCT02029612
- Testing
- Nicotine Patch, Phone Counseling, Questionnaires
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
HIV/AIDS
Oregon PrEP at Home Study
This demonstration study will evaluate the real-world implementation of long-acting cabotegravir (CAB-LA) for HIV pre-exposure prevention (PrEP) through a partnership between the OHSU Tele-PrEP Program (TPP) and the OHSU Home…
- Trial name
- OR-PrEP@Home (NCT05949203)
- Testing
- Cabotegravir Injection
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intravenous Drug Abuse
Pre-exposure Prophylaxis (PrEP) for People Who Inject Drugs (PWID)
People who inject drugs (PWID) experience high risk of HIV acquisition. Antiretroviral pre-exposure prophylaxis (PrEP) is an efficacious biomedical HIV prevention strategy for high risk HIV-uninfected individuals including PWID…
- Trial name
- NCT03869671
- Testing
- PrEP uptake/adherence intervention, Harm reduction standard of care
- Sponsor
- Boston University
Acquired Immunodeficiency Syndrome, HIV Infections
Computerized HIV/Sexually Transmitted Disease (STD) Prevention Program
The purpose of the current study is to test a computerized HIV/STD prevention program with heterosexual African Americans. The hypothesis is that those exposed to the program will increase their correct and consistent use of…
- Trial name
- TIPSS (NCT00947947)
- Testing
- Tailored Information Program for Safer Sex
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Counseling and Testing, HIV Infections
An Educational HIV Pre-Test Counseling Video Program for Off Hours Testing in the ED: A Randomized Control Trial
This study compared the educational effectiveness of a ten-minute pre-test counseling video with the usual practice of a session with an HIV counselor.
- Trial name
- NCT00218907
- Testing
- Educational video
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- North Bronx Healthcare Network
Human Immunodeficiency Virus
Human Immunodeficiency Virus Pre-exposure Prophylaxis Program in General Practice
The Human Immunodeficiency Virus (HIV) epidemic persists in France, with approximately 6000 new cases per year. Various prevention tools against HIV exist, including condoms, regular testing, Post-Exposure Prophylaxis (PEP), HIV…
- Trial name
- PrEPInTheCity (NCT06258876)
- Testing
- PrEP in general practice
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adolescent Behavior, Risk Reduction Behavior
HIV/AIDS Orphaned and Vulnerable Children Public Health Evaluation
The PHE study is a two-year longitudinal study evaluating two interventions for reducing depression and HIV risk behaviors among highly vulnerable adolescents in the Eastern Cape of South Africa.
- Conditions
- Adolescent Behavior, Risk Reduction Behavior, Stress, Psychological
- Trial name
- PHE (NCT02386878)
- Testing
- Interpersonal Psychotherapy for Groups (IPTG), Vhutshilo 2
- Volunteers
- 2,302 people
- Sponsor
- Tulane University School of Social Work
HIV Infections
Evaluation of the Population-level Impact of PMTCT Option B+ in Zimbabwe
This study evaluates the impact of Zimbabwe's program for the prevention of mother-to-child HIV transmission (PMTCT) on vertical transmission of HIV infection and HIV-free survival among infants exposed to HIV.
- Trial name
- NCT03388398
- Volunteers
- 30,642 people
- Sponsor
- University of California, Berkeley
Opioid Use, Opioid Use Disorder
Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP
The purpose of this study is to provide medication for opioid use disorder (MOUD) with buprenorphine and naloxone, or bup/nx, pre-exposure prophylaxis (PrEP) for HIV prevention, and/or hepatitis C treatment for persons who inject…
- Conditions
- Opioid Use, Opioid Use Disorder, Risk Reduction, Hiv
- Trial name
- PARTNERUP (NCT05108935)
- Testing
- Suboxone, Truvada, Mavyret
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Hiv
Finishing HIV Project
This study aims to learn how to help enable healthy behaviors and lower the risk of HIV among Latinx Men.
- Trial name
- NCT06406049
- Testing
- Control group-Standard Health Promotion, Social network intervention
- Where
- United States
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV Infection
Positive Change Agents Program-Tanzania (Evaluation)
The Appreciative Inquiry Change Agents (CA) program (NAMWEZA) intends to address broad societal issues by engaging HIV-positive leaders as 'change agents' in their communities.
- Trial name
- NCT01693458
- Testing
- Appreciative Inquiry Change Agents (CA) program (NAMWEZA)
- Where
- Tanzania
- Volunteers
- 1,046 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
HIV
Cambodia Integrated HIV and Drug Prevention Implementation Program
HIV risk among female entertainment and sex workers (FESW) remains high and use of amphetamine-type stimulants (ATS) significantly increases this risk.
- Trial name
- CIPI (NCT01835574)
- Testing
- Conditional cash transfer and cognitive-behavioral aftercare
- Where
- Cambodia
- Volunteers
- 1,198 people
- Sponsor
- University of California, San Francisco
HIV-infection/Aids, Breast Feeding
Promoting Exclusive Breastfeeding Among HIV Infected Women in a PMTCT Program
This study evaluates strategies aimed at promoting exclusive breast feeding for 6 months followed by continued breastfeeding for the next 6 months with introduction of complementary foods among HIV infected women in a resource…
- Trial name
- EBF (NCT03069235)
- Testing
- Family member / peer support, Enhanced intervention with counselor support, standard of care
- Volunteers
- 218 people
- Sponsor
- Johns Hopkins University
HIV Prevention
Testing a Gender-inclusive HIV Prevention Program
If, over time, data suggest the intervention impacts HIV preventive behavior at the population level, it will be unique in that it can be quickly and cost effectively scaled up to impact thousands of trans girls and nonbinary…
- Trial name
- NCT06586151
- Testing
- Transcendent Health, Text Messaging with Information
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Opioid-use Disorder, HIV Prevention Program
Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services
The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exposure prophylaxis (PrEP) adherence and support services (CoMPASS) to…
- Trial name
- CoMPASS (NCT04738825)
- Testing
- Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
- Where
- 6 sites in United States
- Volunteers
- 526 people
- Sponsor
- Yale University
Male Reproductive Problem
Effect of Formal Letter of Invitation on Male Partner Involvement at Antenatal Care Clinic
Prevention of mother to child transmission (PMTCT) of human immune deficiency virus (HIV) program requires great male participation in achieving a sustained reduction of mother-to-child transmission of HIV.
- Trial name
- NCT06171503
- Testing
- letter of invitation on MI in PMTCT service
- Where
- Ethiopia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jimma University