Clinical trials: HIV Antiretroviral Therapy (ART) Adherence
HIV, Pregnancy
Cash Transfers to Pregnant Women With HIV
The goal of this study is to evaluate the effectiveness and implementation of an unconditional cash transfer intervention to improve mental bandwidth, ART adherence, and postpartum retention among pregnant women with HIV in…
- Conditions
- HIV, Pregnancy, HIV Antiretroviral Therapy (ART) Adherence, Post-partum
- Trial name
- NCT07226492
- Testing
- Unconditional Cash Transfer (UCT)
- Where
- 8 sites in Botswana
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
HIV, HIV Infections
Evaluation of Effectiveness of Pharmaceutical Care on the Adherence of HIV-Positive Patients to Antiretroviral Therapy
INTRODUCTION: Studies prove that the pharmaceutical care (PC) increases the adherence to the antiretroviral; thus, they increase the undetectable viral load.
- Trial name
- PC-HIV (NCT00959361)
- Testing
- pharmaceutical care
- Where
- Brazil
- Volunteers
- 332 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
HIV Disease Progression
Acceptability, Feasibility and Effectiveness of Online Peer Support Group for ART Adherence Among Youth
In Uganda, Youth living with HIV/AIDS (YLHIVA) enrolled in HIV treatment experience suboptimal treatment adherence and have lower viral load suppression (VLS) rates compared to younger children or adults.
- Trial name
- NCT05688709
- Testing
- WhatsApp peer support group
- Where
- 3 sites in Uganda
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Hiv, Medication Adherence
Development of a Silica Microparticle Taggant System to Measure ART Adherence
Developing technologies to help measure and provide tools to support medication-taking behaviors (medication adherence) is an important step to ending the human immunodeficiency virus (HIV) epidemic.
- Conditions
- Hiv, Medication Adherence, Compliance, Medication
- Trial name
- TruTag (NCT06465862)
- Testing
- TruTag System, Biktarvy Pill
- Sponsor
- Brigham and Women's Hospital
HIV Infections
Telephone Support to Improve Adherence to Anti-HIV Medications
This study tested a system of nursing telephone support to determine if it improves adherence to antiretroviral therapy (ART) in at-risk, treatment-experienced people.
- Trial name
- NCT00988442
- Testing
- Enhanced nursing telephone support, Standard care
- Where
- 16 sites in United States
- Volunteers
- 59 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV
Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence
The goal of Suubi+Adherence is to examine the impact and cost associated with an innovative intervention to increase adherence to HIV treatment for HIV-infected adolescents.
- Trial name
- NCT01790373
- Testing
- Suubi+Adherence, Bolstered Standard of Care
- Where
- 2 sites in United States, Uganda
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Antiretroviral Therapy (ART) Adherence Among Adolescents Living With HIV
Adaptive Text Messaging and Non-Monetary Incentives to Sustain ART Adherence Among Adolescents Living With HIV in Ethiopia
Many adolescents living with HIV have difficulty taking their medicine on time, which can make it less effective and affect their health.
- Trial name
- NCT07377760
- Testing
- Non-adaptive reminder text messaging, Adaptive interventions, The control arm
- Where
- Ethiopia
- Volunteers
- 327 people
- Sponsor
- Arba Minch University
HIV Infection
Use of Incentives to Retain Drug Users in HIV Therapy
In many urban centres including Vancouver's Downtown Eastside, there is a high rate of HIV infection among users of illicit drugs.
- Trial name
- Incentives-2 (NCT01488942)
- Testing
- monetary reinforcer
- Where
- Canada
- Volunteers
- 139 people
- Sponsor
- University of British Columbia
Hiv Infection With Antiretroviral Therapy Indication, CD4 Below 350/µL or Below 15%
Zidovudine / Lamivudine + Nevirapine Twice Daily, Versus Tenofovir + Lamivudine + Nevirapine Once Daily in ARV-Naive Patients
The study will compare the immuno-virological efficacy, and safety, of a once daily antiretroviral combination (tenofovir + lamivudine + nevirapine) versus a twice daily association (fixed dose combination of…
- Trial name
- NCT00199979
- Testing
- Nevirapine
- Where
- France
- Volunteers
- 250 people
- Sponsor
- MEDEX
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV, Adherence
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive…
- Conditions
- HIV, Adherence, Sexual Behavior, HIV Infections
- Trial name
- Cell-POS (NCT01118767)
- Testing
- Cell phone intervention
- Where
- 2 sites in Peru
- Volunteers
- 210 people
- Sponsor
- Universidad Peruana Cayetano Heredia
HIV/AIDS, Substance Abuse
Directly Observed Therapy for Community-Released HIV+ Prisoners
The aim of this study is to develop effective interventions for HIV-infected prisoners who are released to the community. The intervention that we will study will be directly observed therapy (DAART/DOT) and we will compare this…
- Trial name
- Connect (NCT00786396)
- Testing
- Directly administered antiretroviral therapy
- Where
- 2 sites in United States
- Volunteers
- 151 people
- Sponsor
- Yale University
HIV, AIDS
Cell Phone Intervention to Support Antiretroviral Therapy (ART) Adherence in Kenya
A clinical study to evaluate the use of cell phones to support drug adherence and follow-up of patients taking antiretroviral therapy (ART) for treatment of HIV.
- Conditions
- HIV, AIDS, HIV Infections
- Trial name
- NCT00830622
- Testing
- Cell Phone Intervention
- Where
- Kenya
- Volunteers
- 536 people
- Sponsor
- University of Manitoba
Human Immunodeficiency Virus
Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs
The purpose of this study is to assess the tolerability, adherence and efficacy of single tablet dolutegravir/abacavir/lamivudine antiretroviral therapy in people living with HIV with a history of injection drug use (IDU)…
- Trial name
- TAISTR (NCT02659761)
- Testing
- dolutegravir/abacavir/lamivudine
- Where
- Ireland
- Volunteers
- 33 people
- Sponsor
- University College Dublin
HIV/AIDS
Quantifying Drug Adherence and Drug Exposure to Antiretroviral Therapy
The purpose of this study is to evaluate cumulative exposure to tenofovir diphosphate (TFV-DP) using dried blood spots (DBS) in treated HIV-infected patients who are receiving a TFV-based regimen.
- Trial name
- 2104 (NCT02012621)
- Where
- United States
- Volunteers
- 807 people
- Sponsor
- University of Colorado, Denver
Substance Related Disorders, HIV
Yoga Intervention for Substance Use and ART Adherence in Community Reentry
People with HIV and a substance use disorder who are reentering the community from prison or jail face the dual risks of relapse and interruptions in adherence to antiretroviral therapy (ART) medication.
- Trial name
- NCT02492893
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Smoking Cessation
Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients
The purpose of this study is to learn if a mindfulness-based smoking cessation smartphone app can help people quit smoking and stay on antiretroviral therapies.
- Conditions
- Smoking, Smoking Cessation, HIV
- Trial name
- NCT03999411
- Testing
- Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
HIV/AIDS, Adherence, Medication
Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy
1. Determine the "dose-response" relationship between a cash transfer amount and HIV viral suppression at 6 months 2. Identify the most effective cash transfer size to increase the proportion of people living with HIV infection…
- Conditions
- HIV/AIDS, Adherence, Medication, Adherence, Patient
- Trial name
- NCT03351556
- Testing
- Active Arm 1, Active Arm 2
- Where
- 4 sites in Tanzania
- Volunteers
- 530 people
- Sponsor
- University of California, Berkeley
Human Immunodeficiency Virus, Mental Disorder
Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study
This study seeks to improve mental health, pregnancy, and HIV outcomes among pregnant and postpartum women living with HIV with common mental health disorders in Kenya.
- Trial name
- NCT06117163
- Testing
- Collaborative Care Model
- Where
- Kenya
- Volunteers
- 900 people
- Sponsor
- University of Colorado, Denver
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse
Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Environments
The investigators developed the Kisoboka ("It is possible") Intervention to address limitations of existing evidence-based interventions to optimize treatment as prevention among men living with HIV who drink alcohol at hazardous…
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse, HIV Infection, Alcohol Use Disorder
- Trial name
- Kisoboka (NCT06771843)
- Testing
- Kisoboka, Behavioral Economics, Motivational Interviewing
- Where
- Uganda
- Volunteers
- 716 people
- Sponsor
- San Diego State University