Clinical trials: Gynecological Tumors
Endometrial Neoplasms, Ovarian Neoplasms
Questionnaire Study for Gynecological Cancer Survivors
The purpose of this study is to evaluate the quality of life of long-term gynecologic cancer survivors.
- Conditions
- Endometrial Neoplasms, Ovarian Neoplasms, Uterine Cervical Neoplasms, Vulvar Neoplasms
- Trial name
- NCT00391664
- Testing
- Psychosocial
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- U.S. Army Medical Research and Development Command
Breast Cancer, Ovarian Cancer
Intermittent Fasting Accompanying Chemotherapy in Gynecological Cancers
The aim of this trial is an evaluation of the effectiveness of intermittent fasting as a supplementary therapy in patients with breast cancer and ovarian cancer in respect to quality of life, reduction of side effects and…
- Trial name
- FIT2 (NCT03162289)
- Testing
- Fasting, Vegan
- Where
- 8 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Cervical Cancer, Ovarian Cancer
Clinical Study on the Safety, Pharmacokinetics, and Efficacy of ScTIL (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Gynecological Malignancies
The purpose of this study is to evaluate the safety and clinical efficacy of ScTIL in the treatment of recurrent or refractory cervical cancer, ovarian cancer and malignant trophoblastic tumor, to evaluate the pharmacokinetic…
- Conditions
- Cervical Cancer, Ovarian Cancer, Malignant Trophoblastic Tumor
- Trial name
- NCT05342506
- Testing
- Toripalimab + ScTIL
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Metastatic or Recurrent Gynecological Tumors
Single Arm Phase I Trail of Autologous Tumor Infiltrating Lymphocyte Injection (GT202) in the Treatment of Metastatic or Recurrent Gynecological Tumors
A prospective, open-label, non-randomized, Phase 1 study evaluating autologous tumor infiltrating lymphocyte injection (GT202) in the treatment of metastatic or recurrent Gynecological tumors.
- Trial name
- NCT05238818
- Testing
- Autologous Tumor Infiltrating Lymphocyte Injection (GT202)
- Where
- China
- Volunteers
- 36 people
- Sponsor
- XinWu
Hernia Incisional, Suture Materials
Fascial Abdominal Closure Evaluation
FACE (Fascial Abdominal Closure Evaluation) Trial is a prospective, single center, open-label, randomized trial of Duramesh versus PDS loop suture for midline incision fascial abdominal closure evaluation in patients with…
- Conditions
- Hernia Incisional, Suture Materials, Duramesh
- Trial name
- FACE (NCT07683546)
- Testing
- DURAMESH, (Ethicon) PDS II 1-0 double loop
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Ovarian Cancer, Endometrial Cancer
Biomarkers for Gynecologic Cancer
A novel blood metabolic biomarker, AminoIndexTM (gynecological), was developed for gynecological cancers from over 400 Japanese patient's plasma free amino acid profiles (PFAAs) by a rapid and sensitive LC-MS (Liquid…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Benign Gynecological Disease
- Trial name
- NCT02178462
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Ajinomoto Co., Inc.
Gynecological Cancer
A Study of TQB2450 Combined With Anlotinib in Subjects With Gynecological Cancer
This is a single-arm, open-label, phase Ib clinical trial to evaluate the efficacy and safety of TQB2450 combined with anlotinib in subjects with gynecological cancer, including 34 ovarian cancer，34 endometrial cancer，22 cervical…
- Trial name
- NCT04236362
- Testing
- TQB2450, Anlotinib
- Where
- 5 sites in China
- Volunteers
- 90 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Gynecological Malignancy
A Study of RC48-ADC for the Treatment of HER2-expressing Gynecological Malignancies
This study will evaluate the effectiveness and safety of intravenous injection of RC48-ADC in the treatment of HER2 expression (HER2 positive and HER2 low expression) gynecological malignancies.
- Trial name
- NCT04965519
- Testing
- RC48-ADC
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RemeGen Co., Ltd.
Oncology
Patient Perspective of Telemedicine in Gynecology Oncology
Research question: do patients in a gynecologic oncology practice value the use of telemedicine as an adjunct to in-person visits and in what circumstances might patients not find these visits to be sufficient?
- Trial name
- NCT04624165
- Testing
- Survey
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Breast Cancer
Large Language Models to Aid Gynecological Oncology Treatment
This trial aims to assess the impact of providing medical students with access to large language models, in comparison to treatment guideline pdfs, on treatment concordance with a conventional multidisciplinary tumor board
- Trial name
- EASING (NCT06865534)
- Testing
- Local language model, Guideline pdf
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Ovarian Cancer, Fallopian Tube Cancer
Phase 3 Study of Rucaparib as Switch Maintenance After Platinum in Relapsed High Grade Serous or Endometrioid Ovarian Cancer (ARIEL3)
Patients enrolled into this study will be stratified into 3 groups based on gene mutations identified in their tumor tissue. The purpose of this study is to evaluate patient response to maintenance treatment with rucaparib versus…
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- ARIEL3 (NCT01968213)
- Testing
- Rucaparib
- Where
- 96 sites in United States, Australia and 9 more
- Volunteers
- 564 people
- Sponsor
- pharmaand GmbH
High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion
Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities
The goal of this clinical trial is to learn if an investigational vaginal suppository therapy works to treat low-grade cervical lesions (ASC-US and LSIL) associated with high-risk human papillomavirus (hr-HPV) infection in women.
- Conditions
- High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion, ASC-US, HPV Infection
- Trial name
- NCT07572396
- Testing
- EGCG and Quinine Sulfate Vaginal Suppository
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Amplexd Therapeutics, Inc.
Borderline Ovarian Tumors
Study Describing the Coverage, Cares and the Fertility of Patients of Less Than 45 Years With a Borderline Ovarian Tumor
Retrospective and prospective multi-center study Indication: Fertility-sparing surgery for patients with borderline ovarian tumor and fertility Objectives: Description of the characteristics of the patients of less than 45 years…
- Trial name
- OPTIBOT (NCT03690440)
- Where
- 11 sites in France
- Volunteers
- 176 people
- Sponsor
- Institut Curie
Gynecological Cancer, Immunotherapy
Detection of Circulating Therapeutic Monoclonal Antibodies in Biological Samples of Gynecological Cancer Patients.
Quantification of anti PD-1 mAbs in cancer patients is extremely important to monitor pharmacokinetics and effectiveness of immunotherapy.
- Trial name
- IMMUNO_ASSAY (NCT06797479)
- Testing
- Blood samples for the analysis of sildenafil in plasma
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gynecologic Cancer
PSMA PET and MRI in Gynecological Cancers
The goal of this research is to determine the accuracy of PSMA positron emission tomography (PET) and multi-parametric magnetic resonance (MR) imaging to detect the presence of gynecological cancer cells in the body.
- Trial name
- NCT03302156
- Testing
- PSMA-based 18F-DCFPyL PET tracer
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Endometrial Carcinoma
Trisenox® in Women With Metastatic Endometrial Cancer
The primary purpose of this study is to see whether women who have already received chemotherapy for their endometrial cancer, or who have disease that has spread outside of the uterus, will respond to the drug arsenic trioxide…
- Trial name
- NRR (NCT01184053)
- Testing
- Arsenic trioxide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer, Fatigue
Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer
This is a multicenter randomized trial in breast cancer patients reporting cancer-related fatigue to evaluate the efficacy and safety of Qiseng® based on extract of American ginseng combined with vitamin C from extract of Camu…
- Trial name
- QISEIN (NCT05241405)
- Testing
- QISENG
- Where
- 10 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Francois Baclesse
Brachytherapy, Complementary Approaches
The Effect of Acupressure on Patients Receiving Brachytherapy
This study aimed to use acupressure to reduce anxiety in gynecologic cancer patients receiving brachytherapy. It was also aimed to investigate the effects of acupressure on anxiety, pain, and vital signs.
- Conditions
- Brachytherapy, Complementary Approaches, Gynecological Cancers
- Trial name
- NCT06531551
- Testing
- The group to which Acupressure will be applied in each fraction
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Enhancing Couples Coping
Side by Side - Prediction of Couples' Adjustment to Breast or Gynecological Cancer
The diagnosis and treatment of cancer leads to emotional distress, and major disruptions in role functioning. Traditionally, psychosocial services offer individuals diagnosed with cancer peer group support or individual…
- Trial name
- Side by Side (NCT01073774)
- Testing
- Side by side, couples control condition
- Sponsor
- Technische Universitaet Braunschweig