Clinical trials: Gynecologic Malignancies
Gynecologic Cancer, Anemia, Iron Deficiency
Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS
Iron deficiency has been reported in up to 35% of patients with a gynecologic malignancy. These patients often require surgical intervention to determine the stage and to treat their illness.
- Conditions
- Gynecologic Cancer, Anemia, Iron Deficiency, Surgery
- Trial name
- FORGE (NCT05467319)
- Testing
- Ferric Derisomaltose Injection, Normal saline
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Gynecologic Cancer
Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine Alone
This study may provide evidence for whether or not systemic lidocaine infusion offers significant advantage over truncal regional blocks in gynecology oncology surgery patients in terms of post-operative analgesia, recovery, and…
- Trial name
- NCT03658109
- Testing
- Lidocaine Bolus Infusion, QL block, Saline Bolus Infusion
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gynecologic Cancer, Endometrial Cancer
Mindfulness in Endometrial and Cervical Cancer
Patients with endometrial cancer who will be undergoing surgery or patients with cervical cancer who will be treated with chemoradiation will be randomized to utilize the Headspace smartphone application or not prior to their…
- Conditions
- Gynecologic Cancer, Endometrial Cancer, Cervical Cancer, Quality of Life
- Trial name
- MECCA (NCT04512144)
- Testing
- Headspace Smartphone Application
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Paralytic Ileus, Nausea
The Impact of Preoperative Bowel Exercise on Postoperative Bowel Functions in Gynecologic Malignancies
Gastrointestinal dysfunction is a common complication after abdominal gynecologic oncology surgery. There are numerous studies in the literature addressing the management of bowel function in the postoperative period.
- Conditions
- Paralytic Ileus, Nausea, Defecation Disorder
- Trial name
- IPBEPOBF (NCT06113718)
- Testing
- Abdominal Exercise (digital rectal stimulation, abdominal massage)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Gynecologic Malignant Tumor
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
As human aging, 50% of women will be faced with the threat of cancer, especially gynecological malignancies. Ovarian, cervical and endometrial cancer are three major gynecological malignancies.
- Trial name
- NCT02166515
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiqing, Liang
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malignant Female Reproductive System Neoplasm
Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients
This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment [NST]) to improve function in stage III-IVA gynecologic cancer…
- Trial name
- NCT07608445
- Testing
- Educational Intervention, Goal Setting, Interview
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Endometrium Cancer, Sentinel Lymph Node
Multimedia Aid Gynecologic Counseling and Consent
This is an interventional trial to introduce two short animated videos into preoperative counseling/consent and to compare patient comprehension and satisfaction with a multimedia approach compared to standard of care currently.
- Conditions
- Endometrium Cancer, Sentinel Lymph Node, Perioperative/Postoperative Complications
- Trial name
- NCT03899441
- Testing
- Video
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Gynecologic Cancer, Ovarian Cancer
Gyn Onc Prehab Study
Patients will be randomized to a unimodal or trimodal prehabilitation program prior to surgery for known or suspected gynecologic cancer.
- Conditions
- Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT04298827
- Testing
- Unimodal, Trimodal
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Urinary Retention
Optimal Management of Urinary Catheter in Gyn Onc
This is a combined retrospective observational study that will collect data on urinary catheter removal of patients who underwent pelvic surgery by a gynecologic oncologist to assess timing safety and its implications in…
- Trial name
- NCT05538273
- Testing
- Early removal of urinary catheter postoperatively, Late removal of urinary catheter postoperatively
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- WellSpan Health
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Ovarian Cancer
Bone Health in Gynecologic Cancers-does FOSAVANCE Help?
Women who undergo bilateral oophorectomy and receive chemotherapy are at risk of increased bone loss. At present, despite having a risk factor profile that fits the indications for assessment and treatment there are no routine…
- Trial name
- FOSAVANCE (NCT00593580)
- Testing
- alendronate/cholecalciferol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Gynecologic Cancer, Hereditary Cancer Syndrome
Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment
In this study, the investigators aim to compare a mobile health platform, known as a 'chatbot,' that leverages artificial intelligence and natural language processing to scale communication, to 'usual care' that patients would…
- Trial name
- NCT05562778
- Testing
- Chatbot
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Gynecologic Cancers, Anxiety
Brief Title- Virtual Reality Glasses in Gynecologic Cancer
It was planned to determine the effect of virtual reality glasses used in female patients diagnosed with gynecological cancer and receiving chemotherapy on treatment compliance and anxiety level.
- Trial name
- NCT06760689
- Testing
- virtual reality glasses, scale
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Gynecologic Cancer, Chemotherapy Effect
Improve Cancer-related Cognitive Impairment
Cancer-related cognitive impairment (CRCI), also known as "chemobrain," is the cognitive decline that negatively impacts the majority of cancer patients undergoing chemotherapy, radiation, and/or hormonal treatments.
- Conditions
- Gynecologic Cancer, Chemotherapy Effect, Chemo-brain, Cancer-related Cognitive Difficulties
- Trial name
- NCT05864274
- Testing
- Cognitive training application
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Education, Surgery
Video-based Coaching (VBC) in Gynecologic Surgery
This multi-centre, randomized controlled trial aims to assess the role of video-based coaching (VBC) in residency education in gynecologic and gynecologic oncology surgery.
- Conditions
- Education, Surgery, Gynecologic Cancer
- Trial name
- NCT05086783
- Testing
- Video-based coaching, Standard surgical teaching (master-apprentice model - (MAM))
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gynecologic Surgical Procedures, Enhanced Recovery After Surgery
Prehabilitation Plus ERAS vs ERAS in Gynecological Surgery
Prospective, interventionist, controlled and randomized study to test the effectiveness of multimodal prehabilitation protocol in patients who will undergo gynecological surgery.
- Trial name
- NCT04505111
- Testing
- Prehabilitation Program + Enhanced Recovery After Surgery, Enhanced Recovery After Surgery
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Financial Burden, Financial Toxicity
Proactive Costs of Care Study
The Proactive Costs of Care intervention is an educational intervention designed to help patients deal with the cost of cancer care.
- Conditions
- Financial Burden, Financial Toxicity, Financial Stress, Financial Navigation
- Trial name
- PCOC (NCT07217262)
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Breast Cancer, Lung Cancer
Predicting Cancer Risk With Digital and Molecular Markers
The goal of this study is to identify new markers to predict the risk of developing cancer, primarily breast cancer. For this purpose, researchers will compare data obtained from cancer patients and healthy individuals.
- Conditions
- Breast Cancer, Lung Cancer, Colorectal Cancer, Gynecologic Cancer
- Trial name
- PräDigt (NCT06962670)
- Testing
- Biomaterial collection, BayPass mobile application
- Where
- Germany
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School