Clinical trials: Gynecologic Laparoscopic Surgery, open to volunteers
Gynecologic Laparoscopic Surgery, Regional Anesthesia Block
Transversus Abdominis Plane Block (TAP) Versus Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Laparoscopic Gynecologic Surgeries
Although laparoscopic techniques are considered minimally invasive surgical procedures with lower perioperative pain scores compared to open surgeries, they are still associated with significant levels of pain.
- Trial name
- NCT06995404
- Testing
- TAP Block Group, M-TAPA Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Sleep Disturbance
Perioperative EEG Prediction of Postoperative Sleep Disturbance in Gynecologic Laparoscopic Surgery
Postoperative sleep disturbance is common in patients undergoing gynecologic surgery and may affect postoperative recovery. This prospective observational cohort study will evaluate perioperative EEG changes in patients…
- Trial name
- NCT07857174
- Testing
- Perioperative Electroencephalographic Monitoring
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Ningxia Medical University
Acute Kidney Injury, Subclinical Acute Kidney Injury
Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery
This prospective observational study aims to evaluate early subclinical acute kidney injury associated with pneumoperitoneum and Trendelenburg positioning during gynecological laparoscopic surgery.
- Trial name
- NCT07704242
- Testing
- Pneumoperitoneum and Trendelenburg Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Endometrial Cancer
Low-Residue Diet Versus Rectal Enema Before Laparoscopic Surgery for Endometrial Cancer
The goal of this clinical trial is to compare a standardized 3-day bowel preparation protocol with a rectal enema before laparoscopic surgery for endometrial cancer.
- Trial name
- NCT07702799
- Testing
- Low-Residue Diet, Sodium Phosphate Rectal Enema
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Mahmut Yassa
Colorectal Cancer, Urologic Cancer
Fluid Challenge and Plasma Volume, During Surgery
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique.
- Conditions
- Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders
- Trial name
- FC-VE (NCT05726136)
- Testing
- acetated Ringers, albumin 5%, albumin 20%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Joachim Zdolsek
to Determine Whether Patient Satisfaction With Postoperative Telehealth Follow-up is Non-inferior to In-person Clinic Visits
Outpatient Visits Versus Telehealth for Postoperative Care After Minimally Invasive Gynecologic Surgery
Telehealth, or telemedicine, utilizes technology to deliver clinical care remotely, either in real time or asynchronously, between clinician and patient.
- Trial name
- Telehealth RCT (NCT07420114)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures
Synergistic Effect of Intravenous Lidocaine on Anesthetic Induction and Emergence in Patients Undergoing Laparoscopic Cholecystectomy or Gynecological Surgery
This study aims to evaluate the effect of intravenous lidocaine on consciousness changes during anesthesia in patients undergoing laparoscopic cholecystectomy or gynecologic surgery.
- Conditions
- Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures, Anesthesia and Procedure Related Time Intervals
- Trial name
- Li (NCT07193836)
- Testing
- Normal Saline (0.9% NaCl), Lidocaine, Lidocaine Bolus + Infusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- General Hospital of Ningxia Medical University
Gynecologic Disease, Adnexal Mass
Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach
Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a recent innovation in minimally invasive surgery which has already proven its non-inferiority to conventional abdominal laparoscopy (CAL) for hysterectomy…
- Conditions
- Gynecologic Disease, Adnexal Mass, Adnexal Cyst, Sexuality
- Trial name
- NCT05761275
- Testing
- Elective cystectomy, Elective oophorectomy, Elective salpingectomy
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- Jean Dubuisson
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain, Shoulder Pain
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after…
- Trial name
- NCT07400146
- Testing
- Instillation of Bupivacaine with epinephrine over the diaphragm
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pain, Post-operative, Pneumoperitoneum
Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain
The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain.
- Conditions
- Pain, Post-operative, Pneumoperitoneum, Urogynecologic Surgery
- Trial name
- NCT07631728
- Testing
- Pulmonary recruitment maneuver, Trendelenburg position
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankita Gupta
Ovarian Cysts, Laparoscopic Gynecologic Surgery
A Randomized Controlled Trial Study Comparing Adnexal Surgery by vNOTES or Laparoscopy
The aim with the study is to compare postoperative pain after vNOTES adnexal surgery versus laparoscopic adnexal surgery. Women aged 18 and above with an indication for adnexal surgery for benign gynecological pathology or…
- Conditions
- Ovarian Cysts, Laparoscopic Gynecologic Surgery, vNOTES
- Trial name
- ADNOLA (NCT06964594)
- Testing
- vNOTES adnexal surgery
- Volunteers
- 200 people
- Sponsor
- Region Skane
Pelvic Organ Prolapse (POP), Synthetic Mesh
Safety and Performance of a Pelvic Floor Mesh Implant for Laparoscopic Sacrocolpopexy (ProGYNious)
The purpose of this clinical investigation is to collect clinical data about the ProGYNious Mesh based on a prospective clinical investigation.
- Conditions
- Pelvic Organ Prolapse (POP), Synthetic Mesh, Laparoscopic Surgery, Gynecologic Laparoscopic Surgery
- Trial name
- ProGYNious (NCT07497321)
- Testing
- Surgical mesh for pelvic organ prolapse repair (ProGYNious)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Post Operative Pain, Acute
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia
Pregabalin is a structural analogue of gamma amino butyric acid (GABA). It binds to presynaptic alpha-2-delta subunit of voltage gated calcium channels in the brain and the spinal cord.
- Trial name
- NCT05150795
- Testing
- Pregabalin 150mg, Fentanyl 100 micrograms ampoule
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Gynecologic Cancer
The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery
The aim of the study was to determine whether the use of different mechanical ventilation modes in patients with Trendelenburg position and CO2 insufflation affects respiration and cerebral oxygenation due to postoperative…
- Conditions
- Anesthesia, Gynecologic Cancer, Mechanical Ventilation Complication
- Trial name
- NCT06482983
- Testing
- Mechanical Ventilation Mode
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Umraniye Education and Research Hospital
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Gynecologic Laparoscopic Surgery
COMPARISON OF OXIDANT-ANTIOXIDANT LEVELS WITH STRESS HORMONES IN SPINAL ANESTHESIA AND GENERAL ANESTHESIA IN LAPAROSCOPIC TUBE LIGATION
The aim of this observational study is to investigate the effect of anesthesia method applied in laparoscopic tubal ligation on stress factors in women aged 15-45.
- Trial name
- LAP TUBE LİG (NCT06710522)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- KADİR TEOMAN
Laparoscopic Surgery, Gynecologic Oncology Patient
The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology
Laparoscopic surgery, characterized by minimal invasiveness, rapid recovery, and shorter hospital stays, has been widely adopted in Gynecologic Oncology.
- Conditions
- Laparoscopic Surgery, Gynecologic Oncology Patient, Liposomal Bupivacaine, Transversus Abdominis Plane Block
- Trial name
- NCT07458295
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital