Clinical trials: Gynecologic Laparoscopic Surgery
Post Operative Nausea and Vomiting (PONV)
Efficacy of Adding Oral Amisulpride to Dual Prophylaxis for Postoperative Nausea and Vomiting in Patients at High Risk for Nausea and Vomiting Undergoing Gynecological Surgery
Amisulpride is a potent antagonist of dopamine D2 and D3 receptors, both implicated in the emetic response when activated. It is currently used intravenously for the prevention of chemotherapy-induced and postoperative nausea and…
- Trial name
- NCT06887621
- Testing
- Encapsulated amisulpride 50 mg (matched for color, weight, smell and size)
- Where
- Brazil
- Volunteers
- 276 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Shoulder Pain, Nausea
Decreasing Upper and Shoulder Pain After Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01433874
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline infusion, combined group
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Postoperative Pain
Intraperitoneal Atomization of Ropivacaine During Gynecologic Laparoscopic Surgery
Pain following laparoscopic surgery continues to be a clinically important problem with 80% or more patients requiring opioid analgesia post-operatively to control their pain.
- Trial name
- NCT01623635
- Testing
- Ropivacaine
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Padova
Quality of Recovery, Gynecologic Surgery
Effect of Preoperative Duloxetine on Quality of Recovery After Outpatient Laparoscopic Surgery
The objective of this study is to determine the effect of preoperative duloxetine on postoperative quality of recovery after ambulatory surgery, specifically laparoscopic gynecological surgery.
- Conditions
- Quality of Recovery, Gynecologic Surgery, Laparoscopy
- Trial name
- NCT02351440
- Testing
- duloxetine
- Where
- United States
- Sponsor
- Northwestern University
Colorectal Cancer, Urologic Cancer
Fluid Challenge and Plasma Volume, During Surgery
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique.
- Conditions
- Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders
- Trial name
- FC-VE (NCT05726136)
- Testing
- acetated Ringers, albumin 5%, albumin 20%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Joachim Zdolsek
Gynecologic Disease
ERAS Versus Conventional Care Following Gynecological Laparoscopic Surgery
This prospective randomized comparative study aims to compare Enhanced Recovery After Surgery (ERAS) protocol versus conventional perioperative care in women undergoing benign gynecological laparoscopic surgery.
- Trial name
- NCT07832838
- Testing
- Enhanced Recovery After Surgery Protocol, Conventional Perioperative Care
- Volunteers
- 100 people
- Sponsor
- Assiut University
the Efficacy of Analgesia of Laparoscopic TAP Block in Minimally Invasive Gynecology Surgeries
Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.
We propose a clinical trial to determine the efficacy of Laparoscopic Transversus Abdominis Plane (LA-TAP) performed intraoperatively compared with usual postoperative analgesia without LA-TAP block.
- Trial name
- TAP (NCT04345341)
- Testing
- TAP block with liposomal bupivacaine and bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Effectiveness of TAP Block Versus Intravenous Analgesia in Postoperative Pain Management Following Gynecologic Laparoscopic Surgery
Optimal postoperative pain control is crucial in laparoscopic gynecologic surgery, particularly within Enhanced Recovery After Surgery (ERAS) protocols.
- Trial name
- NCT07051499
- Testing
- TAP Block Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Foggia
Gynaecologic Cancer
Impact of Peritoneal Gas Drain on Postoperative Pain for Gynaecological Cancer Patients With Minimally Invasive Surgery
This is a phase III, monocenter and randomized study, which evaluates the effectiveness of peritoneal gas drainage on postoperative pain in laparoscopic or robotic laparoscopic gynaecological surgery.
- Trial name
- DRAIN-EXSU (NCT04974125)
- Testing
- Drain, Manual exsufflation
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Oscar Lambret
Laparoscopy
Data Collection of Demographics and Perioperative Care of Patients Undergoing Laparoscopic Surgery
The goal of this clinical research study is to collect information on patients who had or are going to have laparoscopy performed at M. D. Anderson.
- Trial name
- NCT00490126
- Testing
- Laparoscopic Surgery Data Collection
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Opioid Use
Eliminating Narcotic Prescriptions from Outpatient Minimally Invasive Gynecologic Surgery
Laparoscopic gynecologic surgeries are generally very well tolerated procedures, and patients are able to go home on the same day, with a prescription for pain control.
- Trial name
- eNARCOS (NCT04837014)
- Testing
- prescription for regular acetaminophen and naproxen, prescription for regular acetaminophen , naproxen and dilaudid
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Infertility
Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Laparoscopy
To evaluate the efficacy of lidocaine patch applied around wound in laparoscopic gynecologic surgery in reduction of postoperative pain and illus compared to intravenous lidocaine infusion and placebo.
- Trial name
- NCT04506034
- Testing
- lidocaine patches, IV lidocaine, IV saline infusion
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Ovarian Cysts
Intraperitoneal Ropivacaine Nebulization for Pain Control After Gynecologic Laparoscopic Surgery
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 150 mg may prevent the use of morphine during the first day after laparoscopic ovarian cyst surgery.
- Trial name
- NCT01142622
- Testing
- Ropivacaine nebulization, Ropivacaine instillation
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- San Gerardo Hospital
Ovarian Cancer, Cervical Cancer
Sirius in Gynaecological Laparoscopic Surgery
Precision Robotics' Sirius Robotic Flexible Endoscopic System is a new fully integrated compact 3D laparoscopic camera system with a disposable single-use flexible tip that can change its viewing direction.
- Conditions
- Ovarian Cancer, Cervical Cancer, Gynecologic Cancer
- Trial name
- NCT05048407
- Testing
- Gynaecological laparoscopic surgery (Sirius System)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Precision Robotics (Hong Kong) Limited
Reperfusion Injury
Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary…
- Trial name
- NCT02850471
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Post Operative Pain Management
Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia
The investigators noticed that Body Fat Ratio might have great influence on the efficacy of different lipid soluble anesthetics.
- Trial name
- NCT01917045
- Testing
- Sufentanil (R30730, brand name Sufenta), Sufentanil (R30730, brand name Sufenta) + Morphine, Morphine
- Volunteers
- 180 people
- Sponsor
- Peking University First Hospital
Gynecologic Cancer, Surgical Procedure, Unspecified
Laparoscopic Ultrasound Examination: Analysis of Feasibility
This is a prospective cohort study to assess the feasibility of the laparoscopic ultrasound examination, directly by surgeons, during minimally invasive gynaecological surgery.
- Trial name
- LUXA (NCT06278636)
- Testing
- Laparoscopi ultrasound examination
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypothermia Following Anesthesia, Hypothermia
Preoperative Warming Prevents Postoperative Hypothermia in Laparoscopic Gynecologic Surgery. A Randomized Control Trial
This study examined whether 20 minutes of prewarming prior to gynecological laparoscopic surgery prevented inadvertent post-operative hypothermia.
- Conditions
- Hypothermia Following Anesthesia, Hypothermia, Hypothermia, Accidental, Body Temperature Changes
- Trial name
- NCT02518815
- Testing
- 3M Bair Paws Warming System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Michael Garron Hospital
Pelvic Organ Prolapse
Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery
To measure abdominal wall compliance (AWC) during gynaecologic laparoscopy and assess its relation to the pelvic organ prolapse quantification (POP-Q) score of the same individual, and determine a relationship if present.
- Trial name
- AbComp (NCT05012956)
- Testing
- Laparoscopic sacrocolpopexy, gynecologic laparoscopic surgery
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven