Clinical trials: Gulf War Illness
Gulf War Illness
TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis Reset
Gulf War Illness is a condition that affects multiple major organ systems, resulting in a diverse array of symptoms that include debilitating fatigue, memory and cognition difficulties, headaches, sleep disturbances…
- Trial name
- E/M (NCT04254627)
- Testing
- Etanercept, Mifepristone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Nova Southeastern University
Irritable Bowel Syndrome
Effect of Diet on Gulf War Illness
Fermentable Oligo-, Di and Mono-saccharides And Polyols (FODMAPs) are carbohydrates that are poorly digested in intestines. The undigested carbohydrates are fermented in the colon by gut bacteria.
- Trial name
- NCT02881944
- Testing
- Low FODMAP Diet, High FODMAP Diet
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Ashok Tuteja
Gulf War Illness
Q10 for Gulf War Veterans
Goal: The investigators propose to test whether giving the supplement coenzyme Q10 (Q10) improves symptoms and subjective health in Gulf War veterans (GWV) with chronic, multi-symptom health problems.
- Trial name
- GULF (NCT01011348)
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, San Diego
Gulf War Syndrome, Gulf War Illness
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
- Conditions
- Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain
- Trial name
- NCT04182659
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Veterans Medical Research Foundation
Gulf War Syndrome, Headache
Alleviating Headache and Pain in GWI With Neuronavigation Guided rTMS
This study aims to assess the effect of repetitive transcranial magnetic stimulation (rTMS) on Gulf War illness related headaches and pain.
- Trial name
- NCT03030794
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Veterans Medical Research Foundation
Chronic Fatigue Syndrome, Fibromyalgia
Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome
The purpose of this study is: 1. To identify specific set of proteins in the cerebrospinal fluid (fluid surrounding the brain and the spinal cord), that are believed to be seen in Chronic fatigue syndrome (CFS) patients, but not…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Illness, Multiple Chemical Sensitivity
- Trial name
- NCT00810329
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Gulf War Illness
Cognitive Rehabilitation for Gulf War Illness
There are almost 700,000 Gulf War Veterans (GWV) with 25-30% suffering from a devastating multi-symptom illness coined Gulf War Illness (GWI).
- Trial name
- NCT02161133
- Testing
- Problem-Solving Therapy, Health Education
- Where
- 3 sites in United States
- Volunteers
- 268 people
- Sponsor
- VA Office of Research and Development
Gulf War Syndrome, Adult Growth Hormone Deficiency
Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT)
The goal of the GWIT Study is to assess whether growth hormone replacement therapy is a safe and effective treatment for veterans with Gulf War Illness (GWI) and adult growth hormone deficiency (AGHD).
- Trial name
- GWIT (NCT05355272)
- Testing
- Recombinant human growth hormone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Gulf War Syndrome
Ketamine in Veterans With Gulf War Illness
Up to one third of the 700,000 U.S. military veterans of the 1990-91 Gulf War have Gulf War Illness (GWI), a symptom complex characterized by a combination of chronic pain, cognitive impairment, debilitating fatigue…
- Trial name
- NCT04712071
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Baylor College of Medicine
Gulf War Illness, Persian Gulf Syndrome
Understanding GWI: Integrative Modeling
The investigator proposes to perform a Phase I study assessing safety, efficacy, and biomarker response to the therapeutic interventions of Etanercept followed by mifepristone for veterans with Gulf War Illness.
- Conditions
- Gulf War Illness, Persian Gulf Syndrome, Occupational Diseases
- Trial name
- NCT04255498
- Testing
- Etanercept, Mifepristone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- South Florida Veterans Affairs Foundation for Research and Education
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Syndrome, Gulf War Illness
Confirmation of Diet as a Treatment for Gulf War Illness
This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention.
- Trial name
- NCT05675878
- Testing
- Dietary Intervention
- Where
- 3 sites in United States
- Volunteers
- 111 people
- Sponsor
- American University
Gulf War Illness
Probiotic (VSL #3) for Gulf War Illness
The overall objective is to determine whether VSL #3 will improve 1) intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2) non-intestinal symptoms (fatigue, joint pain, insomnia, general stiffness and headache) associated…
- Trial name
- NCT02011542
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Utah
Chronic Multisymptom Illness in Gulf War Veterans
A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness
We propose to conduct placebo-controlled trial of the glucocorticoid receptor antagonist mifepristone in Gulf War veterans (GWV) with chronic multisymptom illness (CMI) to examine its effects on physical and mental health and…
- Trial name
- NCT00691067
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Bronx Veterans Medical Research Foundation, Inc