Clinical trials: Gulf War Illness
Gulf War Illness
Research Examining Gulf War Illness in Our Nations Service Members
At least 1 in 4 of the 700,000 U.S. Veterans who served in the 1990-1991 Gulf War suffer from Gulf War Illness (GWI). Despite considerable research, effective treatments remain elusive.
- Trial name
- REGIONS (NCT01846182)
- Testing
- Duloxetine, Pregabalin
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Gulf War Syndrome
Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex
The adverse impact of Gulf War Syndrome (GWS) on the health of veterans and on the resources of the VA Healthcare System underscores the need to resolve its underlying cause.
- Trial name
- NCT00956150
- Testing
- Lactulose Breath Test, Rifaximin
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Henry C. Lin, MD
Gulf War Illness
"Immunomodulation in GWI (Phlebotomy)"
Gulf War Illness and deployed veterans of the 1990-1991 Persian Gulf War are invited to have a brief history and physical examination to determine their health status, complete questionnaires, then donate about 83 ml of blood.
- Trial name
- NCT04058275
- Testing
- Draw blood (phlebotomy, 83 ml)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Persian Gulf Syndrome
Exercise and Behavioral Therapy Trial (EBT).
This trial is a study of Gulf War era veterans who have unexplained chronic medical symptoms such as pain, fatigue, and/or cognitive difficulties.
- Trial name
- NCT00007748
- Testing
- Aerobic exercise, Cognitive behavioral therapy
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 1,064 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Illness
Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)
Since their return from military service in the 1990-1991 Gulf War, many Veterans have been affected by debilitating symptoms that are not easily explained.
- Trial name
- MINER (NCT03665740)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- VISN 17 Center of Excellence
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Gulf War Syndrome
Telemedicine Treatment for Veterans With Gulf War Illness
Effective treatments have been developed to ameliorate symptom-related distress and reduce unnecessary healthcare utilization using cognitive-behavioral techniques (CBT) .
- Trial name
- NCT00129454
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Gulf War Illness
Gulf War Illness: Evaluation of an Innovative Detoxification Program
Gulf War illness is found in about one fourth of veterans of the 1990-1991 Gulf War and is characterized by persistent memory and concentration problems, headaches, fatigue and muscle and joint pain.
- Trial name
- NCT01672710
- Testing
- plain crystalline niacin, exercise, sauna
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University at Albany
Gulf War Illness
Effects of Botanical Microglia Modulators in Gulf War Illness
The overall objective of this protocol is to test if Gulf War Illness (GWI) involves chronic inflammation that cannot be measured with typical techniques.
- Trial name
- NCT02909686
- Testing
- Boswellia Serrata, Curcumin, Epimedium
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Gulf War Illness
Study of Bacopa in Gulf War Illness Patients
Gulf War Illness is a condition that affects multiple major organ systems, resulting in a diverse array of symptoms that include debilitating fatigue, memory and cognition difficulties, headaches, sleep disturbances…
- Trial name
- NCT04927338
- Testing
- BacoMind® (Bacopa monnieri standardized extract)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Nova Southeastern University
Gulf War Illness
D-cycloserine: A Novel Treatment for Gulf War Illness (GWDCS)
The purpose of this study is to investigate the efficacy of d-cycloserine (DCS) treatment for Gulf War Illness (GWI). Gulf War veterans with Gulf War Illness experience numerous chronic health symptoms, including cognition and…
- Trial name
- GWDCS (NCT02983734)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Gulf War Syndrome
Clinical Evaluation of Montelukast in Veterans With Gulf War Illness
The study addresses the pre-clinical promise of Montelukast (MLK) for improving brain function in veterans with Gulf War Illness (GWI).
- Trial name
- (GWI) (NCT05992311)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Gulf War Illness
Trial of Naltrexone and Dextromethorphan for Gulf War Illness
Veterans of the 1991 Gulf War who developed Gulf War Illness are being studied. Treatments with FDA approved generic drugs are being administered to see if they help with the symptoms of Gulf War Illness, such as chronic fatigue…
- Trial name
- GWI Treatment (NCT02206490)
- Testing
- naltrexone, Dextromethorphan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- East Carolina University
Gulf War Syndrome
Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome
The main goal of the proposed study is to critically evaluate a nonpharmacological and readily available therapy, cranial electrical stimulation (CES) using Alpha-Stim™, and to discover the brain function mechanisms underlying…
- Trial name
- NCT07151248
- Testing
- Cranial electrical/electrotherapy stimulation (CES)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Gulf War Illness
Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI
This project's objective is to identify effective treatments for Gulf War Illness (GWI). The project tests three potential treatments: curcumin, stinging nettle, and resveratrol.
- Trial name
- NCT05377242
- Testing
- Curcumin, Resveratrol, Stinging Nettle
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- University of Alabama at Birmingham
Gulf War Illness
Probiotic (Visbiome) for Gulf War Illness
The overall objective is to determine whether Visbiome will improve 1. intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2.
- Trial name
- NCT03078530
- Testing
- Visbiome, VSL#3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ashok Tuteja
Chronic Pain, Gulf War Illness
Treating Chronic Pain in Gulf War Illness
The purpose of this study is to determine whether yoga is effective for the treatment of chronic pain in Gulf War Illness.
- Conditions
- Chronic Pain, Gulf War Illness, Chronic Illness
- Trial name
- NCT02378025
- Testing
- Yoga Group, Pain Management Wellness Group
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Palo Alto Veterans Institute for Research
Gulf War Illness
Collaborative Specialty Care for Gulf War Illness
Gulf War Veterans (GWVs) with Gulf War Illness (GWI) do not receive the care they should in the Veterans Affairs (VA). The investigators' data show 70% of GWVs with Gulf War Illness (GWI) do not receive treatment recommendations…
- Trial name
- NCT04403295
- Testing
- Collaborative Specialty Care, e-consultation
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- VA Office of Research and Development
Persian Gulf Syndrome, Gulf War Syndrome
Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness
This unblinded Phase II clinical trial will test the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community; practitioners will have had at least 5 years of experience plus…
- Conditions
- Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases
- Trial name
- CARE (NCT06716411)
- Testing
- Acupuncture
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Gulf War Illness, Headache
Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain
The goal of this clinical trial is to create a machine learning algorithm to improve active repetitive transcranial magnetic stimulation (rTMS) treatments for veterans and/or active military personnel by alleviating Gulf War…
- Conditions
- Gulf War Illness, Headache, Muscle and Joint Pain
- Trial name
- SVM - GWI (NCT07325513)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Veterans Medical Research Foundation