Clinical trials: Growth Retardation
Fetal Growth Restriction, Antiphospholipid Syndrome
Antiphospholipid Antibodies and Fetal Growth Restriction
The Antiphospholipid Syndrome is an immune disease where the presence of antibodies directed against cell membrane phospholipids (antiphospholipid antibodies) can cause an hypercoagulable state that causes thrombosis and…
- Trial name
- NCT01538134
- Where
- Panama
- Volunteers
- 90 people
- Sponsor
- Saint Thomas Hospital, Panama
Fetal Growth Retardation, Stillbirth
Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress…
- Conditions
- Fetal Growth Retardation, Stillbirth, Neonatal Respiratory Failure, Neonatal Death
- Trial name
- NCT04640467
- Testing
- Biophsical profile, Cerebroplacental ratio
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Intrauterine Growth Retardation, Feeding Patterns
The Effect of Neonatal Feeding Modalities on Splanchnic Oxygenation
OBJECTIVES: The main purpose of this study was to evaluate the impact of drip versus intermittent feeding on splanchnic oxygenation in preterm infants with intrauterine growth restriction (IUGR).
- Conditions
- Intrauterine Growth Retardation, Feeding Patterns, Splanchnic Hypoperfusion
- Trial name
- NCT05513495
- Testing
- The effect of drip versus intermittent feeding on splanchnic oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ozge Surmeli Onay
Fetal Growth Restriction (FGR)
DIFFUSION WEIGHTED MRI FINDINGS IN FETUSES WITH AND WITHOUT FETAL GROWTH RESTRICTION
This prospective observational study aims to compare fetal brain diffusion-weighted magnetic resonance imaging (DWI) findings in fetuses with and without fetal growth restriction (FGR) and to evaluate the association between…
- Trial name
- NCT07769957
- Testing
- Diffusion-weighted fetal brain MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Intrauterine Growth Restriction, Fetal Growth Retardation
Improving Mothers for a Better PrenAtal Care Trial Barcelona
High risk women for growth restricted fetuses will randomized in the second trimester into different strategies applied to the mothers: a stress reduction program based on mindfulness techniques or a nutrition interventional…
- Trial name
- IMPACTBCN (NCT03166332)
- Testing
- Mediterranean diet, Mindfulness
- Where
- 2 sites in Spain
- Volunteers
- 1,221 people
- Sponsor
- Hospital Clinic of Barcelona
Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis)
Optimization of Cervical Collections in Pregnancy
Fetal cells are not easily obtained from pregnant patients; this curtails testing to assess the health of the fetus and the mother.
- Conditions
- Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis), Preeclampsia, Fetal Growth Retardation
- Trial name
- OCCP (NCT06323187)
- Testing
- Cervical Sampling
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Dr. Sascha Drewlo
Children Born With Serious Intra-uterine Growth Retardation
Saizen in Intra-uterine Growth Retardation
Study of safety of Saizen® in children born with serious intra-uterine growth retardation (IUGR) treated to final height. An open, phase III study involving 17 centers in France.
- Trial name
- NCT01400698
- Testing
- Saizen® A, Saizen® B, Observation only
- Volunteers
- 91 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Preeclampsia, Severe Preeclampsia
Pre-Eclampsia And Growth Restriction: a Longitudinal Study
Preeclampsia may have several causes leading to different characteristics of the pathology. Differentiation between the "type of preeclampsia" would help to treat patients more accurately.
- Conditions
- Preeclampsia, Severe Preeclampsia, Fetal Growth Restriction, Preterm Birth
- Trial name
- PEARL (NCT02379832)
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Fetal Growth Retardation, High-Risk Pregnancy
Routine Ultrasound Screening in the Third Trimester
Late intrauterine growth restriction is infrequently diagnosed with an overall sensitivity of 40 % in low-risk pregnancies. In addition, late intrauterine growth restriction may be associated with intrauterine death and poor…
- Trial name
- RECRET (NCT01594463)
- Testing
- ultrasound examination
- Where
- France
- Volunteers
- 3,760 people
- Sponsor
- University Hospital, Rouen
Fetal Growth Retardation, Pre-Eclampsia
Cardiac Output Monitoring to Predict Pre-Eclampsia and Restricted Growth (COMPaRE)
Pre-eclampsia (PET) and fetal growth restriction (FGR) are common complications of pregnancy that affect up to 15% of pregnancies in the UK.
- Trial name
- COMPaRE (NCT05123677)
- Testing
- Non-invasive haemodynamic assessment, Maternal ophthalmic artery doppler
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Infant, Small for Gestational Age, Infant, Low Birth Weight
KBTH-GIRHL Healthy Birth Weight Study: A Cross-Section
This study was designed and conducted in an effort to establish a comparison group for the Ghana PrenaBelt Trial (NTC02379728). The Ghana PrenaBelt Trial examined the effect, on birth weight, of a belt-like device to help…
- Conditions
- Infant, Small for Gestational Age, Infant, Low Birth Weight, Pregnancy, Sleep
- Trial name
- KBTH-HBWS (NCT03062228)
- Where
- Ghana
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Hypertension, Pregnancy-Induced, HELLP Syndrome
PROTECT-Africa: Biomarker Validation for Preeclampsia Triage
Preeclampsia is a serious high blood pressure condition that can develop during pregnancy. It is one of the leading causes of death and illness for mothers and babies in Africa.
- Conditions
- Hypertension, Pregnancy-Induced, HELLP Syndrome, Eclampsia, Fetal Growth Retardation
- Trial name
- PROTECT-Africa (NCT07810439)
- Where
- Zimbabwe
- Volunteers
- 1,106 people
- Sponsor
- Africa Clinical Research Network (ACRN)
Pregnancy Complications, Pregnancy, High Risk
Active Pregnancy Against COVID-19
Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence.
- Conditions
- Pregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn Morbidity
- Trial name
- ACPREGCOV (NCT04563065)
- Testing
- Exercise program, Healthy lifestyle advise
- Where
- 2 sites in Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Fetal Growth Restriction
Evaluation of the Safety and Performance of Centaflow
The aim of this study is to evaluate the safety and performance of an acoustic approach based on skin-contact microphones as a routine assessment of placental vascular function as predictor of fetal growth restriction.
- Trial name
- NCT04438668
- Testing
- Centaflow and Standard Care, Standard Care
- Where
- 2 sites in Denmark
- Volunteers
- 1,704 people, healthy volunteers welcome
- Sponsor
- Centaflow
Intrauterine Growth Restriction (IUGR), Fetal Growth Restriction (FGR)
Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction
Early-onset placental intrauterine growth restriction (EO IUGR) is associated with a high risk of perinatal morbidity and mortality.
- Trial name
- STRIDERCan (NCT02442492)
- Testing
- Sildenafil
- Where
- 5 sites in Canada
- Volunteers
- 21 people
- Sponsor
- University of British Columbia
Intra-Uterine Growth Retardation
Sildenafil in Sever Intrauterine Growth Retardation
Severe fetal growth restriction (FGR) complicates approximately 0.4% of pregnancies and severely increases the risk of perinatal morbidity and mortality.Sildenafil citrate may offer a potential therapeutic strategy to improve…
- Trial name
- IUGR (NCT03153215)
- Testing
- treatment
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Beni-Suef University
MOPDII, Meier-Gorlin Syndrome
Primordial Dwarfism Registry
The goal of this registry is to collect information on individuals with forms of microcephalic primordial dwarfism as well as related conditions.
- Conditions
- MOPDII, Meier-Gorlin Syndrome, Saul-Wilson Syndrome, Microcephalic Primordial Dwarfism
- Trial name
- NCT04569149
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Nemours Children's Clinic
Microplastic Levels in Placenta and Cord Blood
Comparison of Microplastic Levels in Placenta and Cord Blood Samples of Pregnant Women With Fetal Growth Retardation and Healthy Pregnant Women
In this study, microplastic levels in the placenta and cord blood of pregnant women with fetal growth retardation and healthy pregnant women will be compared in placenta and cord blood samples after delivery.
- Trial name
- NCT05070715
- Testing
- Analyzing of microplastic level
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University