Clinical trials: Goals
Cochlear Implant
Subjective and Objective Results With CI Electrode Types
Background The authors' aim was to compare the influence of various electrode designs on selected objective and subjective clinical outcomes for cochlear implant recipients using the same model of receiver-stimulator, Cochlear™…
- Trial name
- NCT03515473
- Testing
- cochlear implant
- Where
- Hungary
- Volunteers
- 139 people
- Sponsor
- Szeged University
Angiocardiography
The Safety and toleRability of UltraviSt in Patients Undergoing Cardiac CaTheterization (TRUST)
This study is to collect the information of Ultravist® in the patients indicated for the coronary angiography or PCI, like rate of ADR in patients, the dose for different indications, image quality to prove Ultravist the good…
- Trial name
- TRUST (NCT01206257)
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- China
- Volunteers
- 17,513 people
- Sponsor
- Bayer
Malocclusion, Angle Class I
Direct vs Indirect In-House Clear Aligners vs Fixed Appliances in Orthodontic Treatment
Clear aligner therapy has become increasingly popular as an esthetic alternative to conventional braces in orthodontic treatment.
- Trial name
- NCT07687329
- Testing
- Direct In-House Clear Aligners, Indirect In-House Clear Aligners, Fixed Orthodontic Appliances
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- TC Erciyes University
Postoperative Complications
Effects of Intraoperative Goal-Directed Fluid Therapy on the Incidence of Postoperative Complications
Excessive fluid loss is often reported in gastrointestinal surgical patients due to preoperative fasting and bowel preparations.
- Trial name
- NCT02507557
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Musculoskeletal System Disease
Clinical and Biomolecular Assessment for the Monitoring of Patients Undergoing Regenerative Medicine Treatments with Orthobiologics
the aim is to improve the evaluation of the outcomes of regenerative medicine treatments performed in the regenerative medicine centers involved in the study.
- Trial name
- NCT04711551
- Testing
- PRP and related devices to abtain platelet concentrate from whole blood, medullary and adipose tissue and related devices
- Where
- 2 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Ischemia, Stroke
Edoxaban for TIA and Acute Minor Stroke
Transient ischemic attack (TIA) or minor ischemic stroke has a high risk of early recurrent stroke. As the golden standard, aspirin effect modestly on acute ischemic stroke, and slightly increase the risk of intracerebral…
- Conditions
- Ischemia, Stroke, Cerebral Infarction
- Trial name
- NCT02221102
- Testing
- Aspirin, edoxaban
- Where
- China
- Volunteers
- 3,700 people
- Sponsor
- Xijing Hospital
Major Non-cardiac Surgery
Goal Directed Hemodynamic Management and Renal Outcome After Major Non-cardiac Surgery
This study is designed to compare renal outcome of patients following major non-cardiac surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.
- Trial name
- IROM (NCT01035541)
- Testing
- PiCCO® Monitoring
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Technical University of Munich
Nose Deformities, Acquired
Objectives and Measures Dimensions Nasal Resistance of Preterm and Term (MODERN)
During the resuscitation of preterm infants, withdrawal of non-invasive ventilation is difficult. In a recent study in children gestational age <30 weeks of amenorrhea (SA), definitive withdrawal rate from the first attempt to…
- Trial name
- MODERN (NCT02815345)
- Testing
- Rhinometry
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Surgical Procedures, Operative
Arterial Pulse Waveform Contour Analysis for Intraoperative Goal Directed Therapy in Major Abdominal Surgery
This study evaluates whether using information from a special arterial blood pressure monitor to guide how much fluid is given during surgery changes how long a patient stays in the hospital after the surgery.
- Trial name
- NCT01082614
- Testing
- Vigileo
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Loma Linda University
Virtual Reality, Anesthesia
HoloLens: an Objective Alternative to the Operator's Memory
Neuraxial anesthesia has traditionally been a 'blind' technique relying on users' feel and skill, both are subjective, lack complete accuracy and influenced by patient's physique variations that are quite challenging, and lead to…
- Conditions
- Virtual Reality, Anesthesia, Epidural
- Trial name
- Hololens (NCT04028284)
- Testing
- HoloLens-guided epidural, US-guided epidural
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Hypotension,Controlled
Correlation Analysis of the Effects of Management Pressure Goals and Control Volume Goals in Patients in Spinal Surgery
The investigators study 160 patients undergoing spinal surgery.Participants will be randomly divided into study group and control group.The study group will receive controlled hypotension by nitroglycerin and be divided into 3…
- Trial name
- NCT03917004
- Testing
- Nitroglycerin
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liang Bing
Stroke Rehabilitation, Triage
The Way to Goal-oriented Therapy Planning in Neurorehabilitation
The aim of this feasibility study is to investigate whether target-oriented treatment planning can be maintained in the rehabilitation of stroke patients using the existing classification (LIMOS) and evidence-based specialist…
- Trial name
- NCT03720106
- Testing
- GOAL therapy plan
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Rehaklinik Zihlschlacht AG
Nonamnestic Mild Cognitive Impairment, Cognitive Dysfunction
Online Cognitive Rehabilitation of Executive Dysfunction in Nonamnestic MCI
Nonamnestic mild cognitive impairment (naMCI) is a prodromal state characterized by deficits in executive functioning, a collection of higher-order abilities involved in organization, planning, inhibition, and complex reasoning.
- Conditions
- Nonamnestic Mild Cognitive Impairment, Cognitive Dysfunction, Cognitive Disorder, Neurocognitive Disorders
- Trial name
- NCT04503798
- Testing
- Online Goal Management Training
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Baycrest
Hypertension, Mobile Application
Development of a Mobile Application Called TansiyoRitim for Hypertension Patients
Based on King's Theory of Goal Success, this project is designed to develop a mobile application called TansiyoRitim for individuals over the age of 18 diagnosed with hypertension.
- Conditions
- Hypertension, Mobile Application, Blood Pressure Control, Treatment Adherence
- Trial name
- NCT07556419
- Testing
- Mobile application, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kafkas University
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation
Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI
Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA.
- Conditions
- Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
- Trial name
- GOALS TH (NCT07190365)
- Testing
- GOALS TH, EDU TH
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Prostate Cancer
The Composite Steep-pulse Treatment Apparatus Used in Prostate Cancer Ablation Therapy
This trial is studying the effects and safety in treating patients from five different centers with local prostate cancer, employing Composite Steep-pulse(High-frequency irreversible electroporation) Treatment Apparatus.
- Trial name
- NCT03838432
- Testing
- Steep Pulse Device
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Second Military Medical University
Healthy
Objective Measurement of Pain Using the Algometer
The development of tools for assessment and management of pain in newborns and children is a high priority and represents a significant unmet need.
- Trial name
- NCT02325284
- Testing
- Pressure Algometer Testing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julia Finkel
Surgery
Goal-directed Fluid Management Versus Conventional Fluid Management in Laparoscopic Hysterectomy
Fluid management is critical in patients undergoing surgery. Goal-directed fluid management (GDFM) protocols have been shown to decrease the length of hospital stay.
- Trial name
- NCT03970928
- Testing
- PVI
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Breast Cancer, Lymphedema
Who and Why do Patients Report Lymphedema After Breast Cancer Treatment Without an Objective Measurable Swelling
Breast cancer related lymphedema (BCRL) at the arm and/or trunk is an extremely dreaded complication after breast cancer treatment due to its chronicity and impact.
- Conditions
- Breast Cancer, Lymphedema, Sensory Processing Disorder
- Trial name
- LymphSens (NCT06324721)
- Testing
- Measurements for breast cancer related lymphedema (volumetric measurements, bioimpedance spectroscopy, bioimpedance analysis, tissue dielectric constant measurements, ultrasonography), Measurements for lymphatic problems (volumetric measurements, tissue dielectric measurement, lymphofluoroscopy), Measurements for sensory processing problems by monofilaments, algometer, goniometer, and neurosensory analyzer
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
The purpose of the study is to evaluate the safety and tolerability of pepinemab in combination with pembrolizumab as first-line treatment and determine a recommended Phase 2 dose (RP2D) in patients with recurrent or metastatic…
- Trial name
- KEYNOTE-B84 (NCT04815720)
- Testing
- pepinemab + pembrolizumab
- Where
- 15 sites in United States
- Volunteers
- 49 people
- Sponsor
- Vaccinex Inc.