Clinical trials: Glutathione
Antioxidant Status
Rapid Effects of a Biofield Patch on Antioxidant Status and Cellular Energy
The goal for this clinical proof-of-concept study is to compare an active biofield skin patch to a placebo patch on antioxidant function and mitochondrial function.
- Trial name
- NCT07314359
- Testing
- Active dermal patch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Progressive Supranuclear Palsy
Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear Palsy
Studies have shown that alpha-lipoic acid and L-acetyl carnitine may have some neuroprotective activities and it is hoped that they could be helpful for people with neurodegenerative illnesses such as progressive supranuclear…
- Trial name
- NCT01537549
- Testing
- alpha-lipoic acid and L-acetyl carnitine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University
Friedreich's Ataxia, FRDA
GABA and GSH in FRDA
The goal of this study is to obtain gamma-aminobutyric acid (GABA) and glutathione (GSH) assessment derived from magnetic resonance spectroscopy (MRS), to be used as a potential biomarker in patients with Friedreich Ataxia (FRDA)…
- Trial name
- NCT07635030
- Testing
- MRI/ MRS (Magnetic Resonance Imaging /Magnetic Resonance Spectroscopy)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Bioavailability Heathy Volunteers, Safety
Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
This study seeks to determine the short-term effects of daily oral supplementation with a new micellar Glutathione formulation (LipoMicel) on the oral absorption and safety of glutathione in healthy volunteers.
- Trial name
- NCT06345950
- Testing
- Liposomal Glutathione, Standard Glutathione, New Micellar Glutathione (Lipomicel)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
Brain Aging
Milk Intervention Study for Brain Aging
The purpose of this study is to learn if increased dairy food consumption helps brain health in older adults by protecting nerve cells from damage.
- Trial name
- NCT02957422
- Testing
- 1% Milk, Control
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Type 2 Diabetes, Oxidative Stress
The Production of Reactive Oxygen Species in Response to Glutathione Supplementation and Acute Exercise
Objectives: The research focus of the study is the production of reactive oxygen species (ROS) in patients with type 2 diabetes (T2D) in response to glutathione (GSH) supplementation and in response to acute exercise.
- Conditions
- Type 2 Diabetes, Oxidative Stress, Mitochondrial Reactive Oxygen Species Production
- Trial name
- DIMITOS (NCT02948673)
- Testing
- Glutathione
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Mild Asthma
Genetic Susceptibility to Ozone in Mild Asthmatic Volunteers
Recent reports have shown that people with asthma who have a particular gene, known as the GSTM1 null gene, are more susceptible to the effect of air pollutants.
- Trial name
- Glutoz (NCT00287365)
- Testing
- ozone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Kidney Disease, Kidney Disease
Adia Med of Winter Park LLC Chronic Kidney Disease Research Study
The goal of this clinical trial is to learn whether a new regenerative treatment called AdiaVita, made from umbilical cord blood-derived stem cells and exosomes combined with glutathione, is safe and can help improve kidney…
- Conditions
- Chronic Kidney Disease, Kidney Disease, Kidney Disease, Chronic, Chronic Kidney Disease (CKD)
- Trial name
- NCT07572890
- Testing
- Umbilical Cord Blood-Derived Stem Cells and Exosomes, Glutathione IV, Glutathione Spray
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Adia Med of Winter Park LLC
Autism, Oxidative Stress
Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism
This study will look at the changes taking place in the blood levels of key markers of oxidative stress. Oxidative stress is the biological equivalent of rust on a car. It changes vital cell chemistry.
- Trial name
- NCT00263367
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The International Child Development Resource Center
Fatty Liver
Alpha-Glutathione-S-Transferase (AlphaGST) and MARINA Index in Metabolic-Dysfunction-Associated-Steatotic-Liver-Disease (MASLD)
AlphaGST represents a liver enzyme whose serologic levels progressively increase in alcoholic and viral chronic hepatitis according to the worsening of liver fibrosis.
- Trial name
- NCT05804955
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- University of Campania Luigi Vanvitelli
Tuberculosis, Pulmonary, HIV/AIDS
RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection
Although tuberculosis is a treatable disease, it is currently the infectious disease with the highest mortality in the world. It is estimated that one-third of the world's population is infected.
- Trial name
- RIPENACTB (NCT03281226)
- Testing
- RIPE (2m) and RI (4m), RIPE+NAC (2m) and RI (4m)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Beta Thalassemia Major Anemia, Hemolysis
The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia Major
The accumulation of unpaired α-globin chains in β-thalassemia major patients may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia.
- Conditions
- Beta Thalassemia Major Anemia, Hemolysis, Oxidative Stress
- Trial name
- NCT03948737
- Testing
- Alpha-Tocopherol
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Alcohol Drinking
Effect of Glutathione on Blood Alcohol and Hangover Symptoms
Glutathione (a tripeptide of 3 amino acids - glutamic acid, cysteine and glycine) plays a great role in homeostasis, especially as a potent anti-oxidant.
- Trial name
- NCT00127309
- Testing
- Glutathione
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Piyavate Hospital
Stroke
SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients
In patients undergoing physical therapy after stroke, extracellular thiol-disulfide balance and intracellular oxidized-reduced glutathione balance levels will be monitored.
- Trial name
- NCT04884555
- Testing
- Standard neurorehabilitation, Thiol-Disulphide Homeostasis, Oxidized-reduced Glutathione Homeostasis
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Health Subjects With Cardiovascular Risk Factors
Sublingual L-GSH Supplementation in Male Subjects With Smoking Habit and/or Hypertension
Background. The antioxidant systems are the main endogenous defense against free radicals, and glutathione seems to play an important role in this mechanism.
- Trial name
- NCT02125045
- Testing
- L-GSH
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Niguarda Hospital
Infertility, Anesthesia
The Effect of Music Therapy on Glutathione Peroxidase, Malondialdehyde and Pain in Oocyt Pick Up Patients.
It is used by music therapists to help the social, physical, emotional, psychological and psychological needs of patients. In a study, music has a positive effect on pain, anxiety, depression, shortness of breath, mood, facial…
- Conditions
- Infertility, Anesthesia, Oxidative Stress, Pain, Postoperative
- Trial name
- NCT04175873
- Testing
- music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Schizophrenia
Schizophrenia, Related Troubles and Glutathione: Clinical Trial. Effects of Oral Administration of N-Acetylcysteine (NAC) on the Brain Glutathione Level and on the Symptoms of Schizophrenia
The results of the study "schizophrenia, related disorders and glutathione" conducted at the Laboratory of Psychiatric Neuroscience (LUNEP) DUPA of Lausanne, reinforce the hypothesis proposed that a deficit intracerebral…
- Trial name
- NCT01506765
- Testing
- N-Acetyl-Cysteine (NAC)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Critically Ill Patients, Cardiac Surgery
Impact Of Antioxidant Micronutrients On Intensive Care Unit (ICU) Outcome
Critically ill patients are generally exposed to an increased oxidative stress, which is proportional to the severity of their condition.
- Conditions
- Critically Ill Patients, Cardiac Surgery, Trauma, Subarachnoid Hemorrhage
- Trial name
- Etude-AOX (NCT00515736)
- Testing
- Selenium (Se), Zinc (Zn), Vitamin C, Vitamin B1, Vitamin E
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Healthy, Diabetes Mellitus Type 1
The Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic Patients
The goal of this clinical trial is to evaluate the effects of low-level light therapy on cellular energy and oxidative stress in healthy adults and patients with Type 1 diabetes.
- Trial name
- PBM-T1D (NCT07833865)
- Testing
- Red and Near-Infrared Light Therapy Pad
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thi-Qar
Oxidative Stress, Redox Imbalance
Oxidative Stress and Antioxidant Enzyme Activities in Elite Female Turkish Cross-Country Skiers
This study is designed to investigate oxidative stress and antioxidant defense biomarkers in elite female cross-country skiers compared with sedentary women.
- Conditions
- Oxidative Stress, Redox Imbalance, Exercise-Induced Physiological Stress
- Trial name
- NCT07181889
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Duvenciler Anadolu Lİsesi