Clinical trials: Glaucoma Surgery
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt
The goal of this randomized controlled clinical trial is to learn whether two minimally invasive bleb-forming glaucoma implants can effectively treat adult patients with open-angle glaucoma who require surgical lowering of…
- Trial name
- MINI-BATTLE (NCT07359547)
- Testing
- XEN®-63 Gel Stent, PRESERFLO™ MicroShunt
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 166 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pediatric Glaucoma
Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract
The aim of this study is to report the effectiveness of phacoaspiration when combined with angle surgery in preventing postoperative glaucoma following pediatric cataract surgery
- Trial name
- NCT05401760
- Testing
- Group A :combined phacoaspiration and angle surgery, Group B : phacoaspiration only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Glaucoma, Open-Angle, Glaucoma, Narrow Angle
Clinical Study Evaluating the Efficacy and Safety of CID v2.2 in Glaucoma Surgery
The purpose of this study is to evaluate the safety and effectiveness of implanting a new version of an interposition supraciliary implant (SV22) as a stand-alone therapy for lowering intraocular pressure (IOP) in patients with…
- Trial name
- SAFARI4 (NCT05625958)
- Testing
- Cilioscleral Interposition Device
- Where
- 5 sites in Spain
- Volunteers
- 29 people
- Sponsor
- Ciliatech
Open-angle Glaucoma (OAG)
5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
This study is designed to collect clinical data at 3, 4, and 5 years postoperatively for participants who completed the CREST Study without having secondary IOP-lowering surgery in the study eye(s).
- Trial name
- CREST-XT (NCT07480343)
- Testing
- CycloPen Micro-Interventional Cyclodialysis System, CycloPen Micro-Interventional Cyclodialysis System Post Cataract
- Where
- 10 sites in United States
- Volunteers
- 250 people
- Sponsor
- Iantrek, Inc.
Open Angle Glaucoma
A Single Center Proof Of Concept Study To Assess Intra And Perioperative Safety Profile Of OMNI Surgical System
The overall objective of this study is to determine the safety and usability of OMNI surgical system in performing canaloplasty and trabeculotomy.
- Trial name
- NCT04530084
- Testing
- OMNI Surgical System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mark Gallardo, MD
Glaucoma, Open-Angle, Cataract Complicated
Evaluation of Phacogoniotomy in Medically-controlled POAG
The goal of this multicenter non-inferiority randomized controlled trial is to compare the efficacy of phacoemulsification with intraocular lens implantation (PEI) combined with goniotomy (GT) and PEI combined with medical…
- Conditions
- Glaucoma, Open-Angle, Cataract Complicated, Goniotomy
- Trial name
- ECO (NCT06201455)
- Testing
- PEI+GT, PEI+MED
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Open-Angle Glaucoma
A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2
The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma.
- Trial name
- NCT00326079
- Testing
- Stent
- Where
- 7 sites in Austria, Germany and 2 more
- Volunteers
- 61 people
- Sponsor
- Glaukos Corporation
Exfoliation Glaucoma, Cataract
Comparison Of iStent to Laser in Exfoliation Glaucoma Helsinki Study Group
The purpose of the study is to investigate the efficacy of an iStent trabecular microbypass stent compared to selective laser trabeculoplasty in combination with cataract surgery in eyes with exfoliation glaucoma (EXF)
- Trial name
- COILEH (NCT04635020)
- Testing
- iStent, SLT-laser, Cataract surgery
- Where
- Finland
- Volunteers
- 285 people
- Sponsor
- Helsinki University Central Hospital
Glaucoma
Evaluation of the Impact of the XEN® Implant on Endothelial Cell Density, 3 Years After Surgery
Glaucoma is a blinding optic neuropathy affecting 80 million people worldwide, with primary open-angle glaucoma being the most common etiology.
- Trial name
- RETROXEN (NCT05904613)
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Glaucoma, Angle-Closure
Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Primary Angle Closure Glaucoma
To evaluate the clinical efficacy (intraocular pressure reduction , success rate, the number of antiglaucoma medication) and safety of ab interno trabeculectomy (AIT) with Trabectome in Chinese PACG .
- Trial name
- NCT02964676
- Testing
- ab interno trabeculectomy with Trabectome, trabeculectomy
- Volunteers
- 246 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Cataract, Glaucoma
To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.
The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative outcomes.
- Trial name
- NCT07425496
- Testing
- disposable Deltran I pressure sensor
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The New York Eye & Ear Infirmary
Glaucoma
Trabeculectomy Versus MicroShunt Implantation in Glaucoma Surgery (TIGER)
Glaucoma is an eye disease causing vision loss if not treated adequately. The prevalence is around 1.5%, exponentially increasing to more than 10% in the elderly.
- Trial name
- NCT07869108
- Testing
- Preserflo MicroShunt, Trabeculectomy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Glaucoma, Open-Angle
Study of an Interposition Supraciliary Implant in Patients With Open Angle Glaucoma
The purpose of this study is to prolong observational follow-up up to 36 months of patients already implanted with a novel interposition supraciliary implant.
- Trial name
- SAFARI FU (NCT05159817)
- Where
- Armenia
- Volunteers
- 19 people
- Sponsor
- Ciliatech
Primary Open Angle Glaucoma
OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma
To gain early evidence of safety and assess the effectiveness of the intraocular pressure (IOP)-lowering effectiveness of the OMNI 3.0 Surgical System in primary open-angel glaucoma (POAG).
- Trial name
- NCT06991270
- Testing
- OMNI 3.0 Surgical System
- Where
- Panama
- Volunteers
- 25 people
- Sponsor
- Sight Sciences, Inc.
Glaucoma, Glaucoma, Open-Angle
XEN45 in the Treatment of Chinese Patients With Primary Open-angle Glaucoma
Glaucoma is the second most common blindness disease in the world, second only to cataracts. The current treatment of glaucoma is mainly to reduce intraocular pressure.At present, two commonly used surgical methods are…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Surgery
- Trial name
- NCT05130554
- Testing
- XEN45 gel stent implantation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Refractory Glaucoma
Ahmed Glaucoma Valve and Single-Plate Molteno Implants in Treatment of Refractory Glaucoma
The purpose of this study is to investigate the efficacy and safety of the Ahmed valve implant (AVI) and the Molteno single-plate implant (MSPI) in eyes with refractory glaucoma during a follow-up period of 24 months.
- Trial name
- NCT00971061
- Testing
- Ahmed valve implant, Molteno single-plate implant (MSPI)
- Where
- Iran
- Volunteers
- 72 people
- Sponsor
- Vanak Eye Surgery Center
Primary Congenital Glaucoma
Visco-Circumferential-Suture-Trabeculotomy Versus Trabeculotomy
comparing outcomes of Visco-Circumferential-Suture-Trabeculotomy in primary congenital glaucoma to trabeculotomy
- Trial name
- NCT04683289
- Testing
- trabeculotomy
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Mansoura University
Glaucoma, Glaucoma Patient
Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management
Glaucoma is one of the leading causes of irreversible vision loss worldwide. Elevated intraocular pressure (IOP) is the most important risk factor for the development and progression of the disease.
- Conditions
- Glaucoma, Glaucoma Patient, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Glaucoma Following Surgery
- Trial name
- NCT07780916
- Testing
- Ab-interno trabeculotomy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Cataract
Symfony Intraocular Lens Retrospective Chart Review
Retrospective chart review of patients with pre-existing ocular pathology who underwent cataract surgery with implantation of the Symfony IOL.
- Trial name
- NCT05111106
- Testing
- Symfony IOL
- Volunteers
- 463 people
- Sponsor
- Austin Eye
Open Angle Glaucoma, Ocular Hypertension
MINIject Global Long-Term Follow-up Study
The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.
- Trial name
- STAR-GLOBAL (NCT04524416)
- Testing
- Minimally invasive glaucoma surgery (MIGS)
- Where
- 9 sites in Colombia, France and 4 more
- Volunteers
- 116 people
- Sponsor
- iSTAR Medical