Clinical trials: Glaucoma, Angle-Closure
Primary Angle Closure Glaucoma
Evaluation of Ocular Biometry in PACD With Two Swept Source Optical Coherence Tomography Devices
Purpose: To investigate agreement between 2 swept source OCT biometers, IOL M.aster700 and Anterion, in various ocular biometry and intraocular lens (IOL) calculations of primary angle-closure disease (PACD).
- Trial name
- NCT05052242
- Testing
- primary angle closure disease
- Where
- Thailand
- Volunteers
- 45 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Ophthalmopathy, Glaucoma
Phaco-Trabeculotomy Vs Phaco-Trabeculectomy
A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.
- Conditions
- Ophthalmopathy, Glaucoma, Glaucoma, Angle-Closure
- Trial name
- PDT vs PT (NCT04683055)
- Testing
- Phacoemulsification combined with trabeculectomy, Phacoemulsificaiton combined with ab-externo trabeculotomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Glaucoma
Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma
Glaucoma affects 66 million people worldwide and is the leading cause of irreversible blindness, and Primary angle-closure glaucoma (PACG) is a major form of glaucoma in Asia.
- Trial name
- NCT01004900
- Testing
- Selective Laser Trabeculoplasty, Travoprost/ Timolol/ Azopt/ Brimonidine
- Where
- Singapore
- Volunteers
- 90 people
- Sponsor
- Singapore Eye Research Institute
Congenital Cataract, Aphakic Glaucoma
Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma
This is a retrospective, nonrandomized comparative trial with historical control to investigate the safety and efficacy of a novel progressive grasping peripheral iridectomy (PGPI) surgical method in preventing aphakic…
- Trial name
- NCT03610295
- Testing
- PPI group, cataract extraction
- Where
- 2 sites in China
- Volunteers
- 87 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Primary Angle Glaucoma Closure Suspect
Danish Angle Closure Prevention Trial
To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.
- Trial name
- DAP (NCT06077253)
- Testing
- Iridotomy
- Where
- 5 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Aarhus
Primary Angle Closure Glaucoma
Comparison of Phaco Surgery With Goniosynechialysis Versus Trabeculectomy in Glaucoma Treatment
The goal of this clinical trial is to learn whether phacoemulsification combined with goniosynechialysis (Phaco-GSL) is as effective and safe as trabeculectomy in treating patients with primary angle-closure glaucoma.
- Trial name
- NCT06952153
- Testing
- Phacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU
- Where
- Vietnam
- Volunteers
- 82 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Chronic Obstructive Pulmonary Disease, Glaucoma, Angle-Closure
Effect of Tiotropium on Eye Findings in the Treatment of Chronic Obstructive Pulmonary Disease
This study aimed to examine the effect of Tiotropium, which is used in the treatment of COPD, on eye symptoms.The study was conducted prospectively. Patients were examined in three groups.
- Trial name
- NCT06525051
- Testing
- Tiotropium
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Giresun University
Primary Angle-Closure Glaucoma
Liwan Eye Study: the Fourth Follow-up
Primary angle-closure glaucoma (PACG) is one of the major causes of blindness affecting more than 20 million patients worldwide.
- Trial name
- NCT06333470
- Testing
- Primary angle closure diseases
- Volunteers
- 600 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma
Will Listening to Music Make it Easier to Take a Visual Field Test?
The purpose of this study is to examine if there is a difference between glaucoma patients having background music and not having background music before visual field testing.
- Trial name
- NCT01027039
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Glaucoma, Angle-Closure
Outcome of GATT Combined With Goniosynechiolysis in Glaucoma Patients With Secondary Synechial Angle Closure.
To evaluate the intraocular pressure reduction effect of combined gonioscopy-assisted transluminal trabeculotomy (GATT) with goniosynechialysis in eyes with secondary synechial angle closure glaucoma.
- Trial name
- NCT06445634
- Testing
- Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Kasr El Aini Hospital
Glaucoma Eye, Open-angle Glaucoma
Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options
Glaucoma surgery currently relies on a wide therapeutic arsenal, ranging from conventional filtering surgeries to minimally invasive glaucoma surgery (MIGS).
- Conditions
- Glaucoma Eye, Open-angle Glaucoma, Closed-Angle Glaucoma, Pseudo Exfoliative Syndrome
- Trial name
- G-SCOPE (NCT07303257)
- Testing
- NEI-VFQ-25 (National Eye Institute Visual Function Questionnaire-25).
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Hospices Civils de Lyon
Glaucoma, Angle-Closure
Angle Closure (Glaucoma) in Caucasians
Rationale: Primary angle closure glaucoma (PACG) causes high rates of blindness, either by means of a painful attack of acute angle closure glaucoma or unnoticed over a period of many years.
- Trial name
- NCT02054403
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Glaucoma, Angle-Closure
Implantation of Capsular Tension Ring in Primary Angle Closure Patients With Zonular Laxity or Dialysis
Primary angle closure glaucoma (PACG) is the main type of glaucoma in China, which includes acute and chronic PACG. According to the International Society of Geographical and Epidemiological Ophthalmology (ISGEO), this spectrum…
- Trial name
- NCT05542290
- Testing
- Capsular tension ring implantation, No capsular tension ring implantation
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tongren Hospital
Acute Angle-Closure Glaucoma
Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma
To investigate the changes of angle structure and intraocular pressure after argon laser peripheral iridoplasty in patients with acute angle closure glaucoma patients whose intraocular pressure could not be controlled by drug…
- Trial name
- NCT04912310
- Testing
- Argon laser peripheral iridoplasty
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ophthalmopathy
Artificial Intelligence Screening on Patients With Primary Angle Closure Glaucoma
The Tomey CASIA (Tomey Corporation, Nagoya, Japan) is a novel rapid imaging device that captures high-quality imaging of the entire anterior chamber of the eye over detailed imaging of a single section.
- Trial name
- AI (NCT03611387)
- Testing
- CASIA 2 OCT
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Acute Primary Angle-closure Glaucoma
Corneal Densitometry in Acute Primary Angle Closure Glaucoma
Purpose: Our purpose was to investigate the laser peripheral iridotomy (LPI) induced changes in corneal densitometry in acute primary angle closure glaucoma (PACG) cases during the post-laser 1 month period.
- Trial name
- NCT04254458
- Testing
- Corneal densitometry
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ulucanlar Eye Training and Research Hospital
Angle Closure Glaucoma, Glaucoma
Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies
Purpose: To evaluate short-term angle opening after argon peripheral iridoplasty using AS-OCT and to report its complications at 1-week and 1-month follow up in patients that did not achieve a satisfactory clinical angle opening…
- Trial name
- ALPIECA (NCT02199158)
- Testing
- Argon Laser Peripheral Iridoplasty
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Glaucoma, Angle-Closure
Phacotrabeculectomy Versus Phacogoniotomy (PVP) in Advanced Primary Angle-closure Glaucoma
A multicenter, parallel, open, non-inferior randomized controlled trial was conducted to compare the effectiveness and safety of phacotrabeculectomy and phacogoniotomy in the treatment of advanced primary angle closure glaucoma…
- Trial name
- PVP (NCT04878458)
- Testing
- phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy, phacoemulsification with intraocular lens implantation combined with trabeculectomy
- Where
- 2 sites in China
- Volunteers
- 124 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Narrow Angle
Intraocular Pressure Control After Anterior Segment Laser - Comparison Between 2 Drugs
The purpose of this study is to compare the intra-ocular (IOP) control efficacy between brimonidine 0.1% vs. 0.2% after laser peripheral iridotomy (LPI).
- Trial name
- NCT01417858
- Testing
- YAG laser peripheral iridotomy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Paraná
Glaucoma, Angle-Closure
Effect of Peripheral Laser Iridotomy Placement on Post-operative Visual Function
To evaluate the influence of superior versus temporal laser peripheral iridotomy location on post-operative visual acuity and contrast sensitivity.
- Trial name
- NCT03352492
- Testing
- Superior laser peripheral iridotomy, Temporal laser peripheral iridotomy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of the Incarnate Word