Clinical trials: Gingivitis and Periodontal Diseases
Gingivitis, Plaque
Self-selection Study of the Toothwave Toothbrush
This study objective is to test the Silk'n Toothwave self-selection, by potential end users. Additionally, this study will evaluate if contraindicated subjects will self-exclude from use of the device and the ability to…
- Conditions
- Gingivitis, Plaque, Calculus, Tooth Discoloration
- Trial name
- NCT04023097
- Testing
- Toothwave toothbrush
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Caries, Gingivitis
Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction
The primary objective of this randomized controlled clinical trial (RCCT) will be to compare the efficacy in reducing the quantity of Streptococcus mutans (S.
- Trial name
- NCT05569850
- Testing
- Brushing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Critically Ill, Oral Health Care
Professional Oral Care and Staff Education in Critically Ill Patients
This study evaluated oral health in critically ill patients admitted to two intensive care units in Budapest, Hungary, and examined whether professional oral care and education of intensive care staff could improve oral hygiene.
- Conditions
- Critically Ill, Oral Health Care, Critical Illness, Oral Care Performance
- Trial name
- NCT07831564
- Testing
- Professional Oral Care, Standard Oral Care, ICU Staff Oral Care Education
- Where
- 2 sites in Hungary
- Volunteers
- 161 people
- Sponsor
- Semmelweis University
Oral Biofilm, Periodontitis
Methodology Antiseptic Application, Influence on Oral Biofilm.
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device.
- Conditions
- Oral Biofilm, Periodontitis, Gingivitis
- Trial name
- NCT02267239
- Testing
- essential oils, immersion, Chlorhexidine, immersion, essential oils, mouthwash
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Gingivitis, Mucositis
Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis
The objective of this study is to evaluate, through clinical, microbiological and immunological tests, the changes during the experimental gingivitis and mucositis model, between teeth and implants, and between patients with a…
- Trial name
- NCT03713567
- Testing
- Experimentally induced plaque
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis.
This is a Phase III, randomized, one-center, parallel group, double blinded, clinical study to evaluate the efficacy of an alcohol-free mouthwash containing CPC+Zn as compared to dental flossing and to rising with an essential…
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases, Gingivitis and Periodontal Diseases
- Trial name
- PGMWII (NCT06598072)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
Periodontal Diseases, Periodontal Inflammation
Oral and Systemic aMMP-8 in Periodontal Disease
Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health.
- Trial name
- NCT04268381
- Testing
- Biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Periodontitis, Periodontal Health
Asprosin Level in Individuals With Periodontal Disease
The aim of this study was to investigate the levels of asprosin hormone and tumour necrosis factor alpha (TNF-α) in gingival crevicular fluids and to compare its level with those in saliva and serum in patients with gingivitis…
- Conditions
- Periodontitis, Periodontal Health, Gingivitis
- Trial name
- ALIGCF (NCT06627972)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Chronic Peridontitis Patients, Chronic Gingivitis
Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels
Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in…
- Conditions
- Chronic Peridontitis Patients, Chronic Gingivitis, Healthy
- Trial name
- NCT02861937
- Testing
- non surgical periodontal therapy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Gingivitis
Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis
Parallel, double blind, randomized, Institutional Review Board (IRB) -approved study involving approximately 160 subjects to complete.
- Trial name
- NCT03214406
- Testing
- Arm & Hammer Advance White Brilliant Sparkle (Test product), Crest Cavity Protection Regular Toothpaste (Negative Control)
- Where
- Canada
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Gingivitis
Stingless Bee Honey Mouth Rinse on Gingivitis
The currently used chemical mouth rinse, chlorhexidine, was prescribed widely among dental practitioners for its ability to kill bacteria.
- Trial name
- NCT07461155
- Testing
- mouth rinse, scaling, oral hygiene education and instruction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Higher Education, Malaysia
Obesity, Periodontitis
Obesity and Oxidative Stress in Patients With Different Periodontal Status
The aim of the study is to evaluate the effect of obesity on periodontally healthy or diseased tissues.Normal weight and obese subjects were analyzed in 6 groups.
- Conditions
- Obesity, Periodontitis, Gingivitis
- Trial name
- NCT02508987
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Oral Hygiene, Photographs
Effect of Pre-treatment Photographs on Oral Hygiene Maintenance in Orthodontic Patients
Dental photography is an essential component of orthodontic treatment. Photographs enable the clinician to keep record of different stages of treatment.
- Trial name
- NCT06010797
- Testing
- Showing Pre-treatment photographs of the patient
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehmat Memorial Post Graduate Dental Teaching Hospital
Gingivitis
Dietary Diversities: Exploring the Influence of Keto Diet and Intermittent Fasting on Oral Health and Salivary Inflammatory Biomarkers
This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of: Periodontal diseases (Gingivitis).
- Trial name
- NCT06597708
- Testing
- keto diet, intermittent fasting with calorie restriction
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingivitis, Pain
Effects Of Low Level Laser Therapy On Tooth Movement,Treatment Related Complications Of Gingivitis,Periodontitis And Pain In Fixed Orthodontic Patients
INTRODUCTION Orthodontic treatment objectives are achieved through the movement of teeth with the application of an external physical force.
- Conditions
- Gingivitis, Pain, Periodontitis, Tooth Migration
- Trial name
- NCT04230096
- Testing
- low level laser therapy
- Where
- Pakistan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Plaque-Induced Gingivitis
Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced Gingivitis
The goal of this clinical trial is to determine whether a mouthwash made from thyme (Thymus vulgaris) helps improve gum health in people with plaque-induced gingivitis.
- Trial name
- NCT07905456
- Testing
- 0.2% Thymus vulgaris mouthwash, Chlorhexidine 0,12%
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Sulaimani
Gingivitis, Periodontal Disease
Touch-to-Teach Interdental Brush Instruction Versus Conventional Guidance on Gingival Health in Patients With Fixed Dental Prostheses
Why is this study being done? People with dental crowns often develop inflamed gums because bacteria accumulate in the tight spaces between teeth that a regular toothbrush cannot reach.
- Conditions
- Gingivitis, Periodontal Disease, Fixed Dental Prosthesis, Dental Plaque
- Trial name
- NCT07636954
- Testing
- Touch-to-Teach interdental brush instruction, Conventional oral hygiene instruction
- Where
- United Arab Emirates
- Volunteers
- 32 people
- Sponsor
- Gulf Medical University
Periodontitis, Gingivitis and Periodontal Diseases
Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures
The primary aim of this study is to evaluate the efficacy of intraseptal anesthesia using 0.3 mL of 4% articaine with 1:100,000 epinephrine (4% Ar+Ep) for periodontal flap surgery in patients with periodontitis and for…
- Trial name
- NCT07212270
- Testing
- periodontal flap surgery, gingivectomy and gingivoplasty
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Dental Plaque, Gingivitis
Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
The purpose of this study is to determine whether the use of a sonic toothbrush alone is more effective than two other toothbrushing protocols on dental plaque elimination in patients with fixed orthodontic appliances.
- Trial name
- NCT00681135
- Testing
- sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04), manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®), manual toothbrush (elmex® Inter X medium toothbrush)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Sebastian Zingler