Clinical trials: Gestational Diabetes, open to volunteers
Pre Diabetes, Postpartum Disorder
Treatment to Regress to Normoglycemia in Women with a Recent History of GDM
The purpose of the study is to determine the efficacy of semaglutide 1mg (Ozempic®) to aid recently postpartum women with dysglycemia and a history of GDM to regress to normoglycemia; thereby filling a gap in efficacious…
- Trial name
- SWEET (NCT04873050)
- Testing
- Semaglutide Pen Injector [Ozempic]
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Woman's
Pregnancy Related
Myo-inositol During Pregnancy to Prevent Gestational Diabetes
Myoinositol is an insulin-like compound that is present in both plant and animal cells. Humans synthesize it naturally, but it is also obtained in our diet.
- Trial name
- NCT06575868
- Testing
- Myo-inositol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Antenatal Care Model, Gestatiaonl Diabetes Mellitus
Effects Of Core Canister Training in Pregnant Women With History of Gestational Diabetes Mellitus
This randomized control trial aims to determine the effects of structured Core Canister Training on muscular thickness, lumbopelvic stability and pelvic floor function in pregnant women diagnosed with GDM
- Trial name
- NCT07889791
- Testing
- core canister training, traditional antenatal exercises
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Gestational Diabetes, Obesity
Growth Hormone Resistance of Beta-cells A
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes…
- Conditions
- Gestational Diabetes, Obesity, Healthy
- Trial name
- GHRB-A (NCT06571487)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Gestational Diabetes, Diagnosis
Outcomes After Unified Versus Standard GDM Diagnosis
Gestational diabetes mellitus (GDM) is a condition that can affect pregnant women during pregnancy and may cause complications for the mother and the baby.
- Conditions
- Gestational Diabetes, Diagnosis, Pregnancy
- Trial name
- UPDATE-GDM (NCT06401629)
- Testing
- NPRP criteria, IADPSG criteria
- Volunteers
- 2,650 people
- Sponsor
- Qatar University
Pregnancy, Type 2 Diabetes
Type 2 Diabetes and Pregnancy a Single-arm Interventional Study
This single-arm interventional study evaluates the MiniMed 780G insulin pump and continuous glucose monitoring (CGM) system in pregnant women with type 2 diabetes enrolled at ≤ 16 weeks gestation.
- Trial name
- pUMPreg2 (NCT07602036)
- Testing
- Automated insulin delivery system - Medtronic 780G
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Poznan University of Medical Sciences
Gestational Diabetes
GDM: Insulin with or Without Metformin?
This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin.
- Trial name
- NCT06781775
- Testing
- Metformin + Insulin, Insulin
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Virginia
Heart Failure With Preserved Ejection Fraction (HFPEF)
Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction
The primary purpose of this study is to evaluate possible association of some heterogeneous circulating biomarkers and anamnestic factors of pregnancy adverse course and outcomes with the prognosis of heart failure with preserved…
- Trial name
- CARPO-HF (NCT06803849)
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
Ultrasound Assessment Of Gastric Volume In Pregnant Women Undergoing Elective Cesarean Section
The primary objective of this study is to compare gastric volume prior to elective cesarean section between pregnant women diagnosed with gestational diabetes mellitus (GDM) and those without GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland
GDM
Healthy Habits During and After Gestational Diabetes
Gestational diabetes mellitus (GDM) is associated with an increased risk of childhood obesity and other adverse health outcomes.
- Trial name
- VALID III (NCT07717515)
- Testing
- Hybrid intervention, Standard Care with Passive Web Access
- Where
- Vietnam
- Volunteers
- 2,546 people
- Sponsor
- Thai Binh University of Medicine and Pharmacy
Gestational Diabetes, Macrosomia, Fetal
Artificial Intelligence and Gestacional Diabetes
Artificial intelligence (AI) technology can assist medical teams in remote monitoring and continuing education of women with gestational diabetes (GDM), potentially improving adherence to interventions and impacting outcomes.
- Trial name
- NCT07345143
- Testing
- monitoring model for women with gestacional diabetes using pharmacological therapy
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- JOSE FERNANDO VILELA-MARTIN
Gestational Diabetes
Gestational Diabetes - PrEvention of PostPartum Diabetes Study
Gestational diabetes is the most common metabolic abnormality during pregnancy. In a Swedish population 2-10% of all pregnant women are diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- PEPP (NCT05112588)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Gestational Diabetes Mellitus (GDM)
Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With Gestational Diabetes
The goal of this randomized clinical trial is to compare metformin and glyburide for controlling blood sugar in pregnant women with gestational diabetes mellitus (GDM) who require treatment with oral medication.
- Trial name
- NCT07802561
- Testing
- Metformin, Glyburide
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Nishtar Medical University
Periodontal Diseases, Pregnancy Complications
Oral Health and Adverse Pregnancy Complications
Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected.
- Conditions
- Periodontal Diseases, Pregnancy Complications, Pregnancy Preterm, Gestational Diabetes
- Trial name
- NCT06110143
- Testing
- Periodontal treatment
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Gestational Diabetes
Early Gestational Diabetes Mellitus
In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) panel published consensus-based recommendations on the diagnosis and classification of hyperglycemia in pregnancy.
- Trial name
- LEMA_GDM (NCT04451915)
- Testing
- late management strategy, early management strategy
- Where
- 10 sites in France
- Volunteers
- 2,010 people
- Sponsor
- University Hospital, Lille
Hypertensive Disorder of Pregnancy, Preeclampsia
MumCare: Mum's Cardiovascular Health for Life
The goal of this randomized clinical trial study is to test the potential benefits of eHealth-assisted follow-up after pregnancy complications that confer and increased risk for premature cardiovascular (CV) disease.
- Conditions
- Hypertensive Disorder of Pregnancy, Preeclampsia, Gestational Hypertension, Gestational Diabetes
- Trial name
- MumCare (NCT05835596)
- Testing
- Access to MumCare app
- Where
- Norway
- Volunteers
- 400 people
- Sponsor
- Oslo University Hospital
Gestational Diabetes, Glucose Metabolism Disorders
Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy
Our study named Integrated Continuous glucose monitoring glycemic cHAracterization during Pregnancy in comparison with oral glucose tolerance test (I-CHAP) aims to establish much needed preliminary evidence in our Asian…
- Conditions
- Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- I-CHAP (NCT06357728)
- Testing
- Continuous glucose monitoring
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes Mellitus (GDM), Postpartum Women
The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy
Gestational Diabetes Mellitus (GDM) currently affects approximately 14% of all pregnancies worldwide. Importantly, the health-related consequences of GDM extend well beyond pregnancy, such that women with a history of GDM have a…
- Conditions
- Gestational Diabetes Mellitus (GDM), Postpartum Women, Uncomplicated Pregnancy
- Trial name
- NCT06911372
- Testing
- Intradermal Microdialysis, Brain Blood Flow Tests, Local Heating
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD