Clinical trials: Gestational Diabetes, open to volunteers
Gestational Diabetes
Early Prediction of Gestational Diabetes in High-risk Women Based on Breath Metabolomics
This study aim to develope novel breath markers of gestational diabetes through a prospective high-risk population cohort study and achieve early prediction of gestational diabetes based on an interpretable machine learning model.
- Trial name
- NCT06753734
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics
Gestational Diabetes Mellitus (GDM)
Gamified Education for Diabetes Self-Management in GDM
Gestational diabetes mellitus (GDM) is a serious public health problem characterized by hyperglycemia that develops during pregnancy and causes significant short- and long-term health risks for both the mother and the fetus.
- Trial name
- NCT07067411
- Testing
- Education Program Using Gamification on GDM
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Yeditepe University
Diabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 2
RIGHTEST iFree 2 CGM in Pregnant Women With Diabetes Study
This study will evaluate the accuracy and safety of the RIGHTEST iFree 2 Continuous Glucose Monitoring (CGM) System in pregnant women with type 1 diabetes, type 2 diabetes, or gestational diabetes.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 2, Diabetes, Gestational
- Trial name
- NCT07889388
- Testing
- RIGHTEST iFree 2 Continuous Glucose Monitoring System
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- Bionime Corporation
Pre-eclampsia, Gestational Diabetes Mellitus (GDM)
Placental Biology in Health and Disease
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR).
- Conditions
- Pre-eclampsia, Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), Pregnancy Induced Hypertension (PIH)
- Trial name
- NCT07470320
- Testing
- There are no interventions for this study
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Gestatiaonl Diabetes Mellitus
Lumbopelvic Stability in Gestational Diabetes Mellitus
The goal of this comparative cross-sectional study is to learn about the effects of gestational diabetes on lumbopelvic stability in primigravida subjects.
- Trial name
- NCT07851753
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Glucose Intolerance After a Recent History of Gestational Diabetes
Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes
Gestational diabetes (GDM) is an important contributor to the increasing prevalence of type 2 diabetes (T2DM). Women with glucose intolerance in early postpartum are a particularly high-risk group with about 50% who will develop…
- Trial name
- SERENA (NCT05569772)
- Testing
- Semaglutide Pen Injector
- Where
- 13 sites in Belgium
- Volunteers
- 252 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gestational Diabetes Mellitus
Home-Ultrasound in Routine High-Risk Care of Patients With Gestational Diabetes Mellitus (GDM)
This study evaluates the impact of incorporating home-ultrasound (home-US) devices into telemedicine care for patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT07158970
- Testing
- Use of the Pulsenmore home ultrasound device for fetal assessment, guided remotely by a physician.
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Wolfson Medical Center
Gestational Diabetes, Vascular Endothelial Function
Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes
The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.
- Trial name
- NCT05946785
- Testing
- Acetylcholine, insulin aspart
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Gestational Diabetes Mellitus (GDM), GDM
Hong Kong Gestational Diabetes Register (HKGDR)
Gestational diabetes mellitus (GDM) is a common condition that affects approximately one out of every six pregnancies. It is defined by elevated levels of blood glucose during pregnancy, usually detected through a glucose…
- Trial name
- NCT07271407
- Where
- Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Pregnancy, Gestational Diabetes Mellitus (GDM)
Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy
This study is a randomized controlled clinical trial designed to evaluate the effect of a polyphenol-rich dietary intervention during pregnancy on endothelial function, oxidative stress biomarkers, and maternal and neonatal…
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Preeclampsia, Hypertension, Pregnancy-Induced
- Trial name
- PREGPOLY (NCT07656532)
- Testing
- Natural Non-Alkalized Cocoa, Polyphenol-Rich Dietary Counseling
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Gestational Diabetes Mellitus (GDM)
Imprinting in Metabolic Diseases - Identifying Epigenetic Mechanisms in Human Gestational Diabetes Through Cell-free DNA
This clinical trials aims to investigate the impact of parental metabolism during pregnancy on fetal epigenetic signatures. The metabolic profiles of both parents will be evaluated through a blood sample collected from the father…
- Trial name
- Epi_GDM (NCT07436195)
- Testing
- Metabolic and epigenetic characterization of parents ans fetuses
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Gestational Diabetes Mellitus (GDM)
The Feasibility Of Expectant Management Versus Induction At 38 Weeks Among Individuals With Gestational Diabetes Mellitus: A Randomized Controlled Pilot Trial (EAGER Pilot Trial)
The EAGER pilot trial is designed to assess the feasibility of a Canadian, multicentre prospective randomized open-label blinded end-point (PROBE) clinical trial addressing whether induction of labour (IOL) at 38 weeks' gestation…
- Trial name
- EAGER Pilot (NCT06641141)
- Testing
- Induction of Labour
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Ottawa Hospital Research Institute
Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled
Maternal Glucose, Cortisol, and Neonatal Outcomes With and Without GDM
This study will compare maternal blood glucose and cortisol responses and neonatal outcomes between women with gestational diabetes mellitus and women without gestational diabetes mellitus who receive epidural analgesia during…
- Trial name
- NCT07870629
- Where
- 3 sites in Vietnam
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Gestational Diabetes
Immediate Postpartum Glucose Tolerance Testing
The objective of this study is to compare the accuracy of a 2hr glucose tolerance test administered during the postpartum hospitalization with the standard of care glucose tolerance testing (administered at 6 weeks postpartum).
- Trial name
- NCT04199676
- Testing
- Glucose tolerance test
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Iron Deficiency Anemia of Pregnancy, Iron Metabolism Disorders
Hepcidin and Glucose Metabolism
Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia (IDA) are common during pregnancy.
- Conditions
- Iron Deficiency Anemia of Pregnancy, Iron Metabolism Disorders, Glucose Intolerance, Gestational Diabetes
- Trial name
- NCT04008147
- Testing
- 100mg iron fumarate, Burgerstein Schwangerschaft & Stillzeit
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Gestational Diabetes Mellitus, Pregnancy, High Risk
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
This is a non-inferiority patient-centered and pragmatic comparative-effectiveness pregnancy randomized controlled trial (RCT) with postpartum maternal and child follow-up through 2 years of 1,572 individuals with gestational…
- Trial name
- DECIDE (NCT06445946)
- Testing
- Metformin, Insulin
- Where
- 26 sites in United States
- Volunteers
- 1,572 people
- Sponsor
- Ohio State University
Gestational Diabetes
Individualized Early Diagnosis and Treatment System of Gestational Diabetes Mellitus (GDM) Based on New Continuous Glucose Monitoring (CGM) Technology
Gestational diabetes mellitus (GDM), as the most common metabolic complication of pregnancy, poses a serious threat to maternal and fetal metabolic health.
- Trial name
- NCT07276945
- Testing
- No interventions
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes, Postpartum
Stelo Real-time Continuous Glucose Monitor Use Postpartum for Lifelong Optimal Wellness
The purpose of this prospective observational study is to gather exploratory and practical use data of the Dexcom Stelo Glucose Biosensing System (Stelo), an over-the-counter (OTC) real-time Continuous Glucose Monitoring (CGM)…
- Trial name
- STELO-GLOW (NCT07356986)
- Testing
- Dexcom Stelo real-time Continuous Glucose Monitor
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Diabetes, Gestational, Diabetes Mellitus, Type 2
Study to Understand Risk Information to Support and Empower
The aim of this trial is to test components of a digital health outreach intervention to promote uptake of postpartum screening and lifestyle programs for diabetes prevention among patients with gestational diabetes (GDM).
- Trial name
- SUNRISE (NCT05752292)
- Testing
- Standard Health Information, Values Affirmation (VA), Tailored Risk Information (TRI)
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of California, Davis