Clinical trials: Gestational Diabetes, open to volunteers
Gestational Diabetes
Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus
1. To compare the effects of metformin, insulin, and their combination with multistrain probiotics on glycemic control and insulin resistance in women with gestational diabetes mellitus (GDM), assessed by FPG, HbA1c, fasting…
- Trial name
- NCT07645001
- Testing
- GRP 1 Tab metformin, GRP 2 Inj insulin, GRP 3 Tab metformin + HI flora sachet
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Gestational Diabetes, Vascular Endothelial Function
Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes
The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.
- Trial name
- NCT05946785
- Testing
- Acetylcholine, insulin aspart
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Gestational Diabetes, Endothelial Dysfunction
Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Women with a history of gestational diabetes mellitus (GDM) are at a 2-fold greater risk for the development of overt cardiovascular disease (CVD) following the effected pregnancy.
- Conditions
- Gestational Diabetes, Endothelial Dysfunction, Physical Inactivity
- Trial name
- NCT06547619
- Testing
- Insulin aspart
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Pre-eclampsia, Gestational Diabetes Mellitus (GDM)
Placental Biology in Health and Disease
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR).
- Conditions
- Pre-eclampsia, Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), Pregnancy Induced Hypertension (PIH)
- Trial name
- NCT07470320
- Testing
- There are no interventions for this study
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Gestational Diabetes Mellitus (GDM)
Assessment of Quality of Life and Psychological Factors Among Women Diagnosed With Gestational Diabetes Mellitus
Summary of Research Protocol Title: Quality of Life and Associated Psychological Factors in Women with Gestational Diabetes Mellitus Background: Gestational Diabetes Mellitus (GDM) is a common metabolic disorder of pregnancy…
- Trial name
- NCT07717424
- Where
- India
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Lovely Professional University
Type 1 Diabetes (T1D), Pregnancy
Automated Insulin for Management of Intrapartum Glycemia
The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Pregnancy, Pre-Gestational Diabetes
- Trial name
- AIMING (NCT06883344)
- Testing
- Automated insulin delivery (AID) system, Intravenous (IV) insulin
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Gestational Diabetes Mellitus in Pregnancy, Hypertension ,Pregnancy
Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and Hypertension
This trial aims to evaluate the effectiveness of a Behavioral Modification Working (BMW) Toolkit in improving glycemic control and blood pressure among pregnant women diagnosed with both GDM and PIH.
- Trial name
- NCT07551011
- Testing
- Behavioral Modification Working (BMW) Toolkit, Routine Antenatal Care
- Where
- 2 sites in Pakistan
- Volunteers
- 220 people
- Sponsor
- University of the Punjab
Gestational Diabetes
Pilot Study of Continuous Glucose Monitoring for Postpartum Glucose Screening
The oral glucose tolerance test (OGTT) is the standard of care in the postpartum period to screen patients with gestational diabetes mellitus (GDM) for persistent dysglycemia.
- Trial name
- NCT07332416
- Testing
- Continuous glucose monitoring for 14 days using the Freestyle LibrePro by Abbott
- Where
- United States
- Volunteers
- 1,300 people
- Sponsor
- Wake Forest University Health Sciences
Gestational Diabetes
Pregnancy and Postpartum CGM in GDM
Gestational diabetes (GDM) is one of the most common complications of pregnancy, and up to one third of women with GDM will have abnormal blood sugars after their pregnancy.
- Trial name
- NCT07174245
- Testing
- continuous glucose monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gestational Diabetes Mellitus (GDM)
The Impact of Myo-Inositol on Glycemic Control and Oxidative Stress in Gestational Diabetes Mellitus
The purpose of this clinical study is to investigate the potential effects of myo-inositol supplementation on changes in glycemic control parameters, oxidative stress, inflammatory biomarkers, psychometric markers, and body…
- Trial name
- NCT07685015
- Testing
- Myo-inositol 2 g + Folic acid 200 µg, Folic acid 200 µg, Insulin therapy
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Type 2 Diabetes, Gestational Diabetes Mellitus
The Next Generation Longitudinal Birth Cohort Diabetes Study
The overall aim of this project is to understand the independent roles of maternal factors, intrauterine exposures, genetic factors, and postnatal environment on the development of obesity and youth-onset type 2 diabetes (T2D) in…
- Trial name
- NextGen (NCT04621396)
- Testing
- Observational screening study
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gestational Diabetes Mellitus
Home-Ultrasound in Routine High-Risk Care of Patients With Gestational Diabetes Mellitus (GDM)
This study evaluates the impact of incorporating home-ultrasound (home-US) devices into telemedicine care for patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT07158970
- Testing
- Use of the Pulsenmore home ultrasound device for fetal assessment, guided remotely by a physician.
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Wolfson Medical Center
Gestational Diabetes Mellitus (GDM), Pregnancy
Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk
This investigator-initiated, non-randomized pilot study evaluates the effect of daily consumption of fermented poi on the maternal microbiome and gestational diabetes risk during pregnancy.
- Trial name
- NCT07446205
- Testing
- Fermented Poi
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Hawaii
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pre-Gestational Diabetes, Type2diabetes
Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching
The ACHIEVE RCT will measure the effect of the intervention (mHealth app with CGM, provider dashboard, and care team coaching) compared to current standard care (prenatal visits, self-monitored blood glucose, and certified…
- Conditions
- Pre-Gestational Diabetes, Type2diabetes, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT05662462
- Testing
- DEXCOM G7 PRO Continuous Glucose Monitor, Patient mHealth app linked to a provider dashboard, Care team coaching for medical and social needs (HUB)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Ohio State University
Gestational Weight Gain, Diet, Healthy
Delivering HOPE (Helping Women Optimize Prenatal Equity)
The overarching research question is: "Does the provision of healthy food (Delivering HOPE) during pregnancy reduce the proportion of women who experience excessive gestational weight gain compared with enhanced standard of care…
- Conditions
- Gestational Weight Gain, Diet, Healthy, Gestational Hypertension, Gestational Diabetes
- Trial name
- NCT06814509
- Testing
- Enhanced Standard of Care (ESoC), Delivering HOPE
- Where
- 8 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Gestational Diabetes Mellitus, Continuous Glucose Monitoring
The Impact of Continuous Glucose Monitoring on Maternal and Infant's Outcomes in Gestational Diabetes
This study will discuss the impact of continuous glucose monitoring on maternal and infant's outcomes in gestational diabetes mellitus, and test the moderating effect of socioeconomic and cultural factors (dietary habits…
- Trial name
- NCT06436326
- Testing
- Continuous glucose monitor, Perinatal nursing care for gestational diabetes, Blood glucose meters (BGM)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Diabetes During Pregnancy, Pregnancy Complications
Effects of Leg Ergometer Versus Arm Ergometer on Blood Glucose, Exercise Tolerance, Weight, and Psychological Stress Among Gestational Diabetic Patients
The current study is a single-blind, parallel-group randomized controlled trial involving 108 participants with diabetes during pregnancy. The trial will compare leg ergometer with arm ergometer.
- Conditions
- Diabetes During Pregnancy, Pregnancy Complications, Pregnancy in Diabetes, Gestational Diabetes Mellitus (GDM)
- Trial name
- GDM (NCT07554287)
- Testing
- Leg Ergometer, Arm Ergometer
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pregnancy, Gestational Diabetes Mellitus (GDM)
Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy
This study is a randomized controlled clinical trial designed to evaluate the effect of a polyphenol-rich dietary intervention during pregnancy on endothelial function, oxidative stress biomarkers, and maternal and neonatal…
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Preeclampsia, Hypertension, Pregnancy-Induced
- Trial name
- PREGPOLY (NCT07656532)
- Testing
- Natural Non-Alkalized Cocoa, Polyphenol-Rich Dietary Counseling
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca