Clinical trials: Geriatric Patient
Postoperative Delirium (POD), Postoperative Sleep Disturbance
Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery
Postoperative delirium (POD) is a common surgical complication.It is associated with a range of negative outcomes such as delayed postoperative recovery,prolonged hospitalization,additional medical expenditures and higher…
- Trial name
- EPISODE (NCT06900205)
- Testing
- Esketamine, 0.9 % saline
- Where
- China
- Sponsor
- RenJi Hospital
Cancer
Deployment of Teleconsulting in Geriatric Oncology for Older Patients
Cancer affects mostly older adults. The development of Geriatric Oncology has greatly improved the management of older patients with the Comprehensive Geriatric Assessments (CGA) being conducted before cancer treatment.
- Trial name
- TeleOncoGe (NCT05619731)
- Testing
- Geriatric oncology tele-consultation and pharmaceutical tele-expertise
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Colorectal Cancer
Laparoscopic Colorectal Resection in Elderly
This is a nested cohort study of OAMBP-01. Patients over 70 years old were enrolled into the data-analysis. The purpose of this study was to examine the feasibility and safety of laparoscopic colorectal resection in elderly…
- Trial name
- NCT05563441
- Testing
- laparoscopic surgery
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Postoperative Delirium, Elderly
The Association Between SIRI and POD in Older Patients
Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness.
- Conditions
- Postoperative Delirium, Elderly, Surgery
- Trial name
- NCT05797194
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Changhai Hospital
Colorectal Neoplasms
Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer
The purpose of this study is to determine if a program of physical activity, nutritional supplements and relaxation techniques is effective at decreasing post operative complications in frail colorectal cancer patients undergoing…
- Trial name
- NCT02502760
- Testing
- Physical Exercise Program, Whey Protein Isolate Powder, Relaxation Techniques
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anesthesia, General
Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade
Asses the effect of the use of Patient State Index (PSI) monitoring on difference in emergence profiles in the elderly (age >65 yrs) population to develop a cost-benefit profile.
- Trial name
- NCT00938782
- Testing
- Sedline
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Hypotension, Anesthesia, Spinal
Jugular Ultrasound for Spinal Hypotension
Spinal induced hypotension is common complication in geriatric group of patient with percentage up to 73% among these group]. the most common causes that enhance occurrence of post spinal anesthesia induced hypotension among…
- Conditions
- Hypotension, Anesthesia, Spinal, Aged
- Trial name
- JUSH (NCT07000188)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Diabetes
Syringes Replacement for Insulin Application for Pens Device in a Population of Elderly Patients With Type 2 Diabetes: Multifactorial Intervention to Improve Glycemic Control
This is a prospective, intervention, randomized, phase IV study. Patients will be included with 60 years or older, both sexes, with HbA1c >8.5% using oral antidiabetics agents and insulin and then we will be randomized by use…
- Trial name
- NCT02517242
- Testing
- Pens Device, Syringe, Monitoring capillary blood glucose with blood glucose monitor, lancet tapes and capillary blood glucose tests (3 tests/day)
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Malnutrition
Acceptability Study of Nutritional Supplements in Hospitalized Elderly Patients
Malnutrition is a major health problem with serious consequences for the quality of life of elderly people: it increases the number of hospitalizations and lengths of stay, worsens functional dependency and increases morbidity…
- Trial name
- CNO Evaluation (NCT02810470)
- Testing
- Fortimel Compact Protein, Fortimel Cream
- Volunteers
- 107 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Acute Myeloid Leukemia
Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AML
The primary purpose of the study is to determine, whether the addition of Sorafenib to standard chemotherapy in elderly patients with newly diagnosed AML improves treatment results (event free survival).
- Trial name
- NCT00373373
- Testing
- Sorafenib
- Where
- 18 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Muenster
Acute Lymphoblastic Leukemia
Liposomal Anthracyclin in the Treatment of Elderly ALL
Phase II multicentric study comparing VAD regimen with continuous infusion over 96 hours of doxorubicin, vincristine and dexamethasone to a 90 minutes infusion of equivalent doses of Dox li-PEG, bolus infusion of vincristine and…
- Trial name
- NCT00600977
- Testing
- Doxorubicine, Doxorubicine pegylated
- Where
- France
- Volunteers
- 60 people
- Sponsor
- French Innovative Leukemia Organisation
Colon Disease
Continuous Infusion of Remidazolam for Colonoscopic Polypectomy in Elderly Patients
To observe the sedative effect of continuous infusion of remidazolam in elderly patients undergoing colonoscopic polypectomy.
- Trial name
- NCT05801757
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tongji Hospital
Gastric Cancer
Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC
The purpose of study is to evaluate the efficacy and safety of postoperative adjuvant chemotherapy with tislelizumab in combination with tegafur-gimeracil-oteracil potassium (S-1 therapy) or tegafur-gimeracil-oteracil potassium +…
- Trial name
- NCT06238167
- Testing
- Tislelizumab, S-1 therapy, low dose SOX therapy
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Lung Neoplasms
The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery
The advantages of thoracoscopic surgery include smaller wounds, fewer postoperative complications, and shortened hospital stay. However,complications such as pain, pulmonary function insufficiency, pneumonia,postoperative…
- Trial name
- VATSMIPMEP (NCT02757092)
- Testing
- Home-based Pulmonary Rehabilitation
- Where
- 2 sites in Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Non-small Cell Lung Cancer
Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung Cancer
This study will evaluate the clinical efficacy of combining Gleevec (imatinib mesylate), a PDGFR antagonist, with front-line, single-agent paclitaxel in a cohort of elderly patients with advanced, non-small cell lung cancer.
- Trial name
- 6137p (NCT01011075)
- Testing
- Imatinib mesylate, Paclitaxel
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- New Mexico Cancer Research Alliance
Anesthesia, Spinal, Elderly
Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients
Fentanyl is a safer alternative than morphine in the management of postoperative pain in elderly. However, pruritus, nausea and vomiting are unwanted side effects of intrathecal fentanyl administration, that can decrease patient…
- Trial name
- NCT04673812
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Kasr El Aini Hospital
Acute Coronary Syndrome Comorbid With Cerebral Atherosclerosis
Tanhuo Decoction for Acute Coronary Syndrome With Cerebral Atherosclerosis in Elderly Patients
The goal of this clinical trial is to learn if Tanhuo decoction works to treat acute coronary syndrome combined with cerebral atherosclerosis in the elderly. It will also learn about the safety of Tanhuo decoction.
- Trial name
- NCT07445581
- Testing
- Tanhuo decoction, standard Western medicine
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Jinggang Xia, MD
Allergic Asthma
The Impact of Breath Exercises by Telemedicine in Patients Aged 8-18 Years With a Diagnosis of Asthma
The goal of this randomized, placebo controlled study is to evaluate the effect of respiratory exercises on asthma attack frequency, symptom and medication scores and quality of life of children with a diagnosis of asthma.
- Trial name
- PHASTER (NCT05749237)
- Testing
- respiratory exercises, relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Anesthesia, Hemodynamic Changes
Hemodynamic Effects of Bilateral and Unilateral Spinal Anesthesia Using the Continuous Pressure Recording Analytical Method.
This randomized controlled study aims to compare the intraoperative hemodynamic effects of unilateral and bilateral spinal anesthesia in elderly patients undergoing elective total hip arthroplasty.
- Trial name
- NCT07789795
- Testing
- Unilateral Spinal Anesthesia, Bilateral Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kayseri City Hospital
Delirium in Old Age, Delirium of Mixed Origin
Music Therapy as a Treatment for Delirium in Acutely Hospitalized Older Patients
The purpose of this study is to assess feasibility and potential effectiveness of two different music interventions for managing delirium symptoms in acute geriatric patients.
- Conditions
- Delirium in Old Age, Delirium of Mixed Origin, Delirium Superimposed on Dementia, Delirium Confusional State
- Trial name
- NCT05398211
- Testing
- Preferred Recorded Music (PRM), Preferred Live Music (PLM)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital