Clinical trials: Geriatric Assessment
Fragility, Sarcopenia
Efficacy of an Intervention to Prevent Frailty in Obese Elderly People (PRE-FROB)
Rationale: There is increasing evidence that obesity may be a risk factor for frailty in the elderly. Obesity favors a state of chronic inflammation and insulin resistance, involves a fatty infiltration of the muscle and an…
- Conditions
- Fragility, Sarcopenia, Obese, Elderly
- Trial name
- PRE-FROB (NCT03000907)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 319 people
- Sponsor
- Consorci Sanitari del Maresme
Sensory Imagination
Evaluation of the Effect of Sensory Imagination on Food Portion Size in School-aged Children
The objective of this intervention is to evaluate the effect of sensory imagination (i.e., imagining the sensory properties of an object) on the choice of food portion size in school-aged children.
- Trial name
- NCT03350932
- Testing
- Sensory imagination about foods
- Where
- France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Pneumococcal Infectious Disease
Clinical Trial of PCV24 in Adults Aged ≥18 Years
A Phase Ib/II clinical trial of 24-valent pneumococcal conjugate vaccine (PCV24)developed by Sinovac Life Science Co., Ltd will be conducted in adults aged ≥18 years.
- Trial name
- NCT07543198
- Testing
- Sinovac Low-dosage PCV24, Sinovac Middle-dosage PCV24, Sinovac High-dosage PCV24
- Where
- China
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Cystic Fibrosis
A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis
The purpose of this study is to evaluate the safety, tolerability and efficacy of VX-121 combination therapy in subjects with cystic fibrosis (CF).
- Trial name
- NCT03912233
- Testing
- VX-121, TEZ, VX-561
- Where
- 26 sites in United States, Germany and 3 more
- Volunteers
- 87 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Pandemic Influenza Disease
Safety, Tolerability and Immunogenicity of Two Doses of Adjuvanted Monovalent Influenza Vaccine Administered to Healthy Adult and Elderly Subjects
The present study, phase III, randomized, controlled, observer-blind, multicenter study, will evaluate safety, tolerability and immunogenicity of two doses of an adjuvanted monovalent influenza vaccine compared with an adjuvanted…
- Trial name
- NCT00841763
- Testing
- Trivalent influenza virus vaccine (TIV), Adjuvanted monovalent influenza virus vaccine (aH5N1), Adjuvanted trivalent influenza virus vaccine (aTIV)
- Where
- 2 sites in Finland, Germany
- Volunteers
- 3,647 people, healthy volunteers welcome
- Sponsor
- Novartis
Physical Activity
Monitoring Physical Activity in Acutely Hospitalized Elderly of 70 Years and Older
This study aims to create reference values regarding the amount of physical activity of acutely hospitalized elderly ≥70 years during hospitalization and aims to create a prediction model in order predict the probability of low…
- Trial name
- MPA (NCT03964714)
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Maastricht University Medical Center
Auricular Fibrillation
Safety Evaluation of Edoxaban in Elderly Patients With Frailty Criteria
The aim of the present study is to prospectively evaluate the safety of Edoxaban.
- Trial name
- NCT05732506
- Testing
- Edoxaban
- Where
- 35 sites in Spain
- Volunteers
- 411 people
- Sponsor
- Galaxia Empírica
Geriatric Disorder, Sarcopenia
Feasibility and Benefits of Group Based Exercise in Residential Aged Care Adults
This study is a pilot study (feasibility and acceptability study), which will compare feasibility and efficacy outcomes between a 12-week Exercise Program and control group in RAC residents.
- Trial name
- NCT02640963
- Testing
- Exercise, Control
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Bond University
Healthy, Physical Examination
Walking Aid Assessment, Arm Strength and Force Under the Foot in Normal Subjects
This study will collect biomedical performance data on walking characteristics in normal, healthy people when walking with walking aids and when walking unaided.
- Conditions
- Healthy, Physical Examination, Middle Age, Aged
- Trial name
- NCT05092932
- Testing
- Normal Foot Force
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
COVID-19, SARS-CoV-2 Infection
A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SCTV01C and SCTV01E in Population Aged ≥12 Years Previously Fully Vaccinated With Inactivated COVID-19 Vaccine
The objective of study is to evaluate the immunogenicity and safety of SCTV01C or SCTV01E as booster compared with Sinopharm inactivated COVID-19 vaccine as booster.
- Trial name
- NCT05239806
- Testing
- SCTV01C, SCTV01E, Sinopharm inactivated COVID-19 vaccine
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Healthy Young Volunteers, Healthy Elderly Volunteers
A Single Dose Study to Assess the Safety, Effects, and Blood and Urine Drug Levels of AZD3293 in Healthy Subjects
This is a single dose study in healthy male and female (of non-child bearing potential) volunteers, to assess the safety, effects on the body, and blood and urine drug levels of AZD3293.
- Trial name
- NCT01739647
- Testing
- AZD3293
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Aging, Sarcopenia
PANGeA - Physical Activity and Nutrition for Quality Ageing
General objectives of the project Defining healthy ageing factors; Setting up content-related bases of the international excellence centre (SLO-ITA) in the field of health of elderly citizens; Raising awareness on the…
- Conditions
- Aging, Sarcopenia, Cognitive Decline
- Trial name
- PANGeA_MM (NCT04899531)
- Testing
- Longitudinal observation
- Where
- Slovenia
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Older Adults (65 Years and Older), Healthy Older Adults
Effects of Assessment and Verbal Feedback on Physical Function and Exercise Adherence in Healthy Older Adults
The goal of this pilot Randomized Controlled Trial (RCT) was to investigate whether the provision of periodic assessment and verbal feedback during an exercise program has an effect on adherence, physical function and…
- Conditions
- Older Adults (65 Years and Older), Healthy Older Adults, Community Dwelling Older Adults
- Trial name
- NCT07437521
- Testing
- Periodic assessment and individualized verbal feedback
- Where
- Greece
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Self-Neglect, Cognitive Ability, General
Multidimensional Assessment and Intervention for Elder Self-Neglect
This study is designed to assess the best method for caring for elders reported to Adult Protective Services (APS) for self-neglect.
- Conditions
- Self-Neglect, Cognitive Ability, General, Geriatric Disorder
- Trial name
- NCT00901706
- Testing
- Comprehensive Geriatric Assessment and APS Usual Care, APS usual care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Frailty, Sarcopenia
Promoting Autonomy Through ExerCisE (PACE) in Outpatient Geriatric Clinics
Physical inactivity is highly prevalent among older adults and is associated with declines in physical function, independence, quality of life, and social participation.
- Trial name
- PACE - OGC (NCT07787663)
- Testing
- PACE
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Université du Québec a Montréal
Acute Myeloblastic Leukemia
Study With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic Leukemia
Standard chemotherapy is capable of eliminating most leukemic blasts in acute myeloblastic leukemia (AML), while leukemia-initiating cells are not sufficiently eradicated.
- Trial name
- TOR-AML (NCT01611116)
- Testing
- sodium chloride solution 0.9%, temsirolimus
- Where
- 5 sites in Germany
- Volunteers
- 33 people
- Sponsor
- Goethe University
Physical Activity
A Smart Physical Examination System for the Health Management in Elderly
The object of this study is to develop a smart physical examination system targeted on the unmet need of the elderly.Furthermore,the ultimate goal is to realize a commercial product aiming at the silver hair market with…
- Trial name
- NCT03842215
- Testing
- smart physical exam
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Cancer, Solid Tumor
Technology to Assess Vulnerable Older Adults With Cancer and Their Caregivers
The goal of this study is to determine the feasibility, reliability, and validity of administering the Geriatric Assessment Tool using these two different computer based survey platforms, REDCap and Support Screen.
- Conditions
- Cancer, Solid Tumor, Hematologic Malignancy
- Trial name
- NCT02041416
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- City of Hope Medical Center
Hip Fractures, Older Patients
Prospective Observational Study Based on a Cohort of Geriatric Patients With Hip Fracture Treated in the Centers Belonging to the GIOG Group
The study aims to collect the clinical activity and management data of the Orthogeriatrics and Orthopedics Units participating in the study on a continuous and long-term basis.
- Conditions
- Hip Fractures, Older Patients, Comprehensive Geriatric Assessment
- Trial name
- GIOG (NCT05150249)
- Where
- 11 sites in Italy
- Volunteers
- 7,000 people
- Sponsor
- University of Milano Bicocca
Colorectal Cancer
Nutrition and Exercise Program for Elderly Colorectal Cancer Patients
The goal of this interventional study is to evaluate the effect of mobile health intervention on frailty, physical fitness, physical activity, and nutritional status of elderly patients with colorectal cancer.
- Trial name
- NCT06502275
- Testing
- Mobile Health Management Frailty Care Program
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology