Clinical trials: Geriatric Anesthesia
General Anesthetics，Emergence Agitation
Advanced Analgesia on the Quality of Recovery After General Anesthesia in Elderly Patients
Recovery period of general anesthesia refers to the period from the end of anesthesia infusion to recovery of the patient after the operation.
- Trial name
- NCT05769530
- Testing
- Nalbuphine，dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Lili Jia
Geriatric Patients, Efficacy, Self
Median and Paramedian Approach in Spinal Anesthesia
Spinal anesthesia (SA) is frequently used as anesthesia in many surgeries such as lower abdominal, inguinal, urogenital, rectal and lower extremities.
- Trial name
- NCT03750877
- Testing
- median approach, paramedian approach
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Postoperative Cognitive Dysfunction
Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients
Purpose: Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients following major surgery and is associated with impaired attention, memory, and executive functions.
- Trial name
- NCT07424729
- Testing
- Mini-Mental State Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Delirium in Old Age, Anesthesia; Adverse Effect
Postoperative Dexmedetomidine in Prevention of Postoperative Delirium
The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are : 1.
- Trial name
- NCT06382961
- Testing
- Dexmedetomidine injection, Sufentanil injection
- Where
- China
- Volunteers
- 287 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Delirium, Anesthesia Awareness
Anesthesia Depth Increases Delirium Incidence
This study aimed to determine whether targeting bispectral index (BIS) readings of 55 (light anaesthesia) was associated with a lower incidence of delirium, dementia (POD), POCD and mortality but higher rates of awareness and…
- Trial name
- NCT05656703
- Testing
- BIS guidance of anesthesia, Standard of Care
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Heidelberg University
Anesthesia; Reaction
Study of Nerve Block Anesthesia for Surgery of Hip Fracture in the Elderly
The investigators aim to examine target-controlled propofol infusion as a technique of anesthesia for surgery of hip fracture under ultrasound guidance lumbar and sacral plexus block or lumbar, sacral and paravertebral nerve…
- Trial name
- NCT02104908
- Testing
- paravertebral nerve, lumbar and sacral plexus block
- Volunteers
- 80 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Anesthesia
Effect of Acupoint Electrical Stimulation on Incidence of Hypotension After Spinal Anesthesia
This study is intended to include elderly patients who are selected to undergo lower limb and pelvic orthopedic surgery under spinal anesthesia.
- Trial name
- NCT05716399
- Testing
- Transcutaneous electric stimulation pretreatment, Transcutaneous acupoint electrical stimulation treatment, Transcutaneous acupoint pseudo electric stimulation
- Volunteers
- 111 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Post-induction Hypotension (PIH), Geriatric Patient
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia.
- Conditions
- Post-induction Hypotension (PIH), Geriatric Patient, Oncologic Disease, Hemodynamic Effects of General Anesthesia
- Trial name
- NCT07294040
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Dolunay ARIK
Ophthalmology
Study on the Effect of Eye-covering Pretreatment on Acute Delirium After General Anesthesia in Pre-school Aged Children
Participants (preschool children), because their cognitive ability and anti pressure ability are obviously weaker than adults, most of the children who have this kind of operation and anesthesia stressors will have perioperative…
- Trial name
- NCT04973150
- Testing
- To explore whether pretreatment with eye covering can reduce the incidence of acute delirium and the score of delirium after general anesthesia in ophthalmology pre-age children.
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Preoperative Anxiety
Daily Screen Exposure and Preoperative Anxiety in Children Aged 2-5 Years
This prospective observational study aims to evaluate whether daily screen exposure duration is associated with preoperative anxiety levels in children aged 2-5 years undergoing elective surgery.
- Trial name
- NCT07425405
- Where
- Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Total Knee Arthroplasty in Geriatric Patients, Spinal Anesthesia
Isobaric Spinal Ropivacaine Versus Hyperbaric Spinal Bupivacaine in Total Knee Arthroplasty in Geriatric Patients
The purpose of this study is to evaluate the efficacy and safety of spinal anesthesia with isobaric ropivacaine, compared with hyperbaric bupivacaine in geriatric patients undergoing lower limb orthopedic surgery.
- Trial name
- NCT02764723
- Testing
- Hyperbaric bupivacaine, Isobaric ropivacaine
- Volunteers
- 52 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Prostatic Cancer
Effect of Adding Sufentanil to Epidural Ropivacaine on Perioperative Metabolic and Stress Responses in Combined General/Epidural Anaesthesia for Geriatric Radical Retropubic Prostatectomy
The purpose of this study is to compare metabolic and stress responses in combined general/epidural anesthesia in geriatric cancer patients.
- Trial name
- NCT01086956
- Testing
- epidural infusion of saline, ropivecaine, or ropivacaine and sufentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min.
- Trial name
- NCT07670923
- Testing
- Propofol Injection, Ciprofol Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- General Hospital of Ningxia Medical University
Colonoscopy, Colorectal Cancer Screening
Water Exchange Colonoscopy in Elderly Patients
Colonoscopy is an important test for detecting colorectal polyps and cancer, but it can cause pain and discomfort, especially in older adults. Traditional colonoscopy uses air to expand the colon.
- Trial name
- NCT07830823
- Testing
- Water exchange colonoscopy, Gas insufflation colonoscopy, Propofol and opioid anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital Of Lin'an District, Hangzhou
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia; Functional
Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children…
- Trial name
- NCT02455921
- Testing
- neostigmine - atropine, Sugammadex
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Middle Aged Patients, Sevoflurane
Minimal Alveolar Concentration of Sevoflurane Inducing Isoelectric Electroencephalogram
Sevoflurane can abolish movement or adrenergic response to noxious stimulus. In order to investigate the effect of sevoflurane on cerebral electrical activity, we determined the MAC of sevoflurane inducing isoelectric…
- Conditions
- Middle Aged Patients, Sevoflurane, General Anesthesia
- Trial name
- NCT01662622
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Huazhong University of Science and Technology
Major Abdominal Surgery
Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery
Elderly patients are usually presented with higher risk for developing cardiopulmonary complications after general anesthesia (GA).
- Trial name
- NCT02534012
- Testing
- Paravertebral block, General anesthesia, Major abdominal surgery
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Cough
90% Effective Infusion Time of Sufentanil to Prevent Induction Cough: A Biased Coin Sequential Study
This single-center, prospective biased coin up-and-down sequential study aims to determine the 90% effective infusion time (ET90) of sufentanil to prevent sufentanil-induced cough (SIC) during the induction phase of general…
- Trial name
- NCT07778953
- Testing
- Sufentanil Citrate
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shiyou Wei
Diabetes Mellitus, Geriatric
Burst Suppressions in Diabetic Elderly
This observational study aims to learn about the effects of diabetes mellitus in intraoperative electroencephalography (EEG) of elderly patients receiving general anesthesia.
- Conditions
- Diabetes Mellitus, Geriatric, General Anaesthesia, Electroencephalography
- Trial name
- NCT07037186
- Testing
- Electroencephalogram
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital