Clinical trials: Geriatric Anesthesia
Adequate Anesthesia With Unimpaired Motor Strength
Comparison of Intrathecal Fentanyl or Sufentanil in 1 mg Bupivacaine Spinal Anesthesia for TURP in Elderly Patients
Adequate sensory block for surgical procedure without side effects and immediate mobilization after surgery are desirable anesthetic technique in various surgeries.
- Trial name
- NCT01608334
- Testing
- Fentanyl, Sufentanil
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Anesthesia, Spinal
The Effect of Spinal Anesthesia on Hemodynamics
In this study, it was planned to provide more stable hemodynamics in geriatric patients with low-dose spinal anesthesia. We will compare 7.5mg hyperbaric bupivacaine with 5mg hyperbaric bupivacaine.
- Trial name
- NCT05896631
- Testing
- 7.5 mg hyperbaric bupivacaine, 5 mg hyperbaric bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Intra-abdominal and Intrapelvic Surgery
Comparison of Intravenous Anesthetics to Volatile Anesthetics on Postoperative Cognitive Dysfunction
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Most patients will receive general anesthesia during surgery. Two groups of general anesthetics are used for this purpose.
- Trial name
- NCT01809041
- Testing
- Sevoflurane, propofol, remifentanil
- Where
- China
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cognitive Dysfunction, Cognitive Disorder, Delirium - Postoperative
the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium
In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.
- Trial name
- NCT06597812
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amasya University
Cognitive Dysfunction
Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)
Deterioration of posoperative cognitive function (DCPO) is an intermediate state between normal cognitive aging and dementia, defined as a cognitive alteration greater than expected for the patient's age and educational level…
- Trial name
- ketaminvsMDZ (NCT04134052)
- Testing
- ketamine sedation versus midazolam sedation
- Where
- Mexico
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Spinal Anaesthesia, Bladder Tumor
A Retrospective Analysis of Spinal Anaesthesia for TURBT Procedures in Elderly Patients
The aim of the study was to evaluate the safety and effectiveness of spinal anesthesia among elderly patients The basic methods for diagnosis and management of bladder cancer include endoscopic procedures (cystoscopy…
- Conditions
- Spinal Anaesthesia, Bladder Tumor, Transurethral Resection
- Trial name
- NCT03221829
- Where
- Poland
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Hypotension on Induction
Perfusion Index as a Predictor of Postinduction Hypotension of General Anesthesia in Geriatric Patients
The influence of hemodynamic aberrations during anesthesia on adverse outcomes is an important clinical issue. There is evidence that hypotension and hypertension during general anesthesia are independently associated with…
- Trial name
- NCT04682717
- Testing
- perfusion index monitoring for postinduction hypotension
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Patients Undergoing Orthopedic Hip Surgery Under Spinal Anesthesia, Orthopedic Hip Sugery in Eldely Patients
Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal Hypotension
This prospective randomized double-blinded clinical trial aims to compare the efficacy and hemodynamic effects of prophylactic norepinephrine infusion versus phenylephrine infusion for prevention of spinal anesthesia-induced…
- Trial name
- NCT07662408
- Testing
- Norepinephrine, Phenylephrine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post-operative Pain
Postoperative Pain in Children Aged From 3 to 5 Years Following Full Mouth Dental Rehabilitation Under General Anesthesia. A Cross-sectional Study. Rehabilitation Under General Anesthesia
the purpose of this study is monitoring Postoperative pain in Children Aged from 3 to 5 years following Full mouth Dental Rehabilitation under General Anesthesia
- Trial name
- NCT03739567
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Delirium, Postoperative Cognitive Dysfunction
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality.
- Trial name
- NCT06176144
- Testing
- Desflurane, Sevoflurane
- Where
- China
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Elderly Patients, Anesthesia
Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
Emergence of elderly patients from anesthesia may face with cognitive dysfunction or agitation such as delirium. There are reports that using dexmedetomidine as a adjuvant for general anesthesia decreased emergence-agitation in…
- Conditions
- Elderly Patients, Anesthesia, Emergence From Anesthesia, Effects of Dexmedetomidine
- Trial name
- CSUHAPM (NCT01851005)
- Testing
- Dexmedetomidine, Sevoflurane, Propofol and Remifentanil
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chosun University Hospital
Anesthesia Intubation Complication
Prediction of Optimal Pediatric Endotracheal Tube Size "Aged Based Formula Versus Ultrasonography"
Background: Ultrasound (US) imaging technique has recently emerged as a novel, simple, portable, noninvasive tool helpful for airway assessment and management.
- Trial name
- NCT03676387
- Testing
- ultrasound guided
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Postoperative Cognitive Dysfunction
Implementation of a Cognitive Training Program to Reduce the Risk of Postoperative Cognitive Dysfunction
Background: The postoperative cognitive dysfunction (POCD) is a frequent complication, often underestimated and leads to a negative impact on the quality of life for patients and their families.
- Trial name
- NCT03620968
- Testing
- cognitive training
- Where
- Spain
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Centro Medico Teknon
Dexmedetomidine, Postoperative Delirium
Different Administration Routes of Dexmedetomidine on Postoperative Delirium
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal…
- Conditions
- Dexmedetomidine, Postoperative Delirium, General Anesthesia
- Trial name
- NCT05952050
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Electroencephalography, Aging
Relationship Between Bispectral Index, EEG Features, and Propofol Effect-site Concentration in Young and Elderly Patients.
The aim of this study is to describe the BIS values and electroencephalographic patterns during total intravenous anesthesia with propofol-remifentanyl, in patients from 18 to 85 years.
- Conditions
- Electroencephalography, Aging, Propofol, Depth of Anesthesia
- Trial name
- NCT04774120
- Testing
- Propofol
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Kidney Injury, Hypotension
A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population
This study proposes to perform a pilot observational study looking at the doses of propofol used for the induction of general anesthesia and its association with the development of hypotension and AKI among elderly patients at…
- Conditions
- Acute Kidney Injury, Hypotension, Anesthesia; Adverse Effect
- Trial name
- NCT03699696
- Testing
- Propofol
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Yale University