Clinical trials: Genital Hemorrhage
Abnormal Uterine Bleeding
Evaluation of the Effects of Levonorgestrel-releasing Intrauterine Device and Dydrogestreone on Quality of Life and Sexual Life in Patients With Abnormal Uterine Bleeding.
This study was retrospectively collected from patients who were diagnosed with abnormal uterine bleeding and received oral dydrogesterone therapy for at least six months or who were administered an intrauterine device containing…
- Trial name
- NCT05474703
- Testing
- SF-36 Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Menstrual Bleeding, Heavy
PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis
The purpose of the study is to learn more about the role of blood clotting factor proteins and cells in menstrual (period) bleeding.
- Trial name
- NCT05862805
- Testing
- Sample Collection and Endometrial Biopsy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Adenomyosis
Norwegian Adenomyosis Study II: Gene Expression Profiling of Adenomyosis
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED II (NCT02197923)
- Testing
- Myometrial biopsy, endometrial biopsy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Menorrhagia, Heavy Menstrual Bleeding
Minitouch Endometrial Ablation System Treatment for Menorrhagia: An Evaluation of Safety & Effectiveness
The EASE Clinical Trial is prospective, multi-center, single-arm (open-label), non-randomized, clinical trial to evaluate the Minitouch Endometrial Ablation System ("Minitouch System") in premenopausal women with menorrhagia.
- Conditions
- Menorrhagia, Heavy Menstrual Bleeding, Heavy Uterine Bleeding
- Trial name
- NCT04267562
- Testing
- Minitouch System
- Where
- 5 sites in United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- MicroCube, LLC
Vaginal Bleeding
Does Skyla Insertion Timing Impact Bleeding?
Women presenting for contraception will be offered the IUS Skyla and study participation. Daily bleeding will be collected for a total of 90 days and correlated with insertion timing and baseline endometrial thickness.
- Trial name
- NCT03074903
- Testing
- Intrauterine system
- Where
- 3 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Endometrial Hyperplasia
Surgicel® & Endometrial Ablation in the Management of Perimenpausal Heavy Menstrual Bleeding
Two hundred \& forty patients aged from 40 to 50 years - complaining of heavy menstrual bleeding that is unresponsive to hormonal lines of treatment \& requesting conservative surgical approach- were randomized into 3 groups…
- Trial name
- NCT03176992
- Testing
- SURGICEL®
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vaginal Bleeding, Loop Electrosurgical Excision
Use of Chitosan Powder in Loop Electrosurgical Excision Procedure
Early treatment of cervical intraepithelial neoplasia (CIN) II-III gives rise to a decrease in the incidence of invasive cervical cancer.
- Trial name
- NCT05661708
- Testing
- Chitosan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Iron-deficiency, Menorrhagia
Measuring Menstrual Iron Loss Using the Iron Isotope Dilution Technique
It is very difficult to quantify menstrual blood loss, the reference method is a tedious one. This is a problem, as it is not conducive to objectively measuring menstrual blood loss and understanding the contribution of menstrual…
- Conditions
- Iron-deficiency, Menorrhagia, Anemia
- Trial name
- MBL_Loss (NCT05788172)
- Testing
- Iron isotope dilution, Alkaline hematin method
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Scrotum Disease, Hydrocele Male
Efficacy of Inhaled Methoxyflurane (Penthrox) as Adjunct for Urologic Procedures Under Local Anesthetic: A Pilot Study
We wish to perform a prospective randomized controlled pilot study at the Men's Health Clinic and Health Science's Centre to assess whether or not the use of Penthrox as an adjunct to LA is associated with improved pain tolerance…
- Conditions
- Scrotum Disease, Hydrocele Male, Spermatocele, Scrotal Hematocele
- Trial name
- NCT07192198
- Testing
- Methoxyflurane, Control
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Contraception
Side Effect Profiles of Brand Name Versus Generic Oral Contraceptives
This is a randomized control trial of Ortho tricyclen versus Trinessa (generic equivalent) to determine if they have similar effects.
- Trial name
- NCT00775190
- Testing
- ortho tricyclen, Trinessa
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Menorrhagia
Ultrasound Appearance of the Endometrium Post Radio-Frequency Ablation
The study primarily aims to evaluate the post ablative endometrium and uterus using transvaginal ultrasound to provide descriptive information as to what may be expected in the 12 months after a NovaSure ablation.
- Trial name
- NCT02584088
- Testing
- Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Menorrhagia
RCT Novasure Versus Novasure + Mirena IUS in the Treatment of Menorrhagia
Hypothesis. Combined treatment with novasure and mirena IUS confers benefit over Novasure alone in the treatment of menorrhagia
- Trial name
- NCT01965587
- Testing
- novasure mirena IUS combined
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walsall Healthcare NHS Trust
Heavy Menstrual Bleeding
HMB- Data Collection Methods
This is an observational study to determine the effect of various treatments prescribed by healthcare providers for heavy menstrual bleeding on bleeding related quality of life (as measured by the Menstrual Bleeding…
- Trial name
- NCT02001324
- Testing
- Web-based data collection, Paper-based data collection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Prostate Cancer, Spine, Open
Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery
The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for…
- Conditions
- Prostate Cancer, Spine, Open, Hip Osteoarthritis, Knee Disease
- Trial name
- NCT06144099
- Testing
- fresh frozen plasma, prothrombin complex concentrate
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Bleeding, Implants
Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users
The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- NCT04205929
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Abnormal Uterine Bleeding, Analgesia
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.
- Conditions
- Abnormal Uterine Bleeding, Analgesia, Paracervical Block
- Trial name
- NCT06653400
- Testing
- paracervical block, Lidocaine, ketorolac
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Iron Deficiency Anemia Treatment, Iron Deficiency
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life.
- Conditions
- Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
- Trial name
- MENO (NCT06798584)
- Testing
- FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Purdue University
Uterine Fibroids, Vaginal Bleeding
Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy
This study will look at the optimal order in which to perform concurrent office hysteroscopy and endometrial biopsy in female patients who present for evaluation of abnormal uterine bleeding at a fibroid and endometriosis…
- Trial name
- NCT02472184
- Testing
- Office hysteroscopy, Endometrial biopsy
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autoimmune Diseases, Lupus Erythematosus, Systemic
Comparative Autoantibody and Immunologic Cell Marker Study
The purpose of this study is to compare immune phenotype, function, and specificity of B lymphocytes from different developmental stages in autoimmune patients to B cells from infectious disease patients and healthy controls.
- Conditions
- Autoimmune Diseases, Lupus Erythematosus, Systemic, Communicable Diseases
- Trial name
- NCT02422875
- Where
- 3 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Emory University
Endometriosis
The Use of MicroRNAs Dysregulation as Potential Biomarkers for Effective Diagnosis of Endometriosis
OBJECTIVES : 1. To investigate the expression pattern of miRNAs operational in inflammation, angiogenesis, hypoxia, apoptosis and cell proliferation in eutopic and ectopic endometrium of patients with endometriosis and normal…
- Trial name
- ENDMET (NCT06168097)
- Testing
- 100 women undergoing surgery (laparoscopy / laparotomy) with presumed diagnosis of endometriosis, women with intraoperative and / or histopathology findings suggestive of endometriosis
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India