Clinical trials: Genital Diseases, Male
Prostate Cancer
Use of Multi-Parametric MRI With Prostate Biopsy for Cancer Diagnosis.
This is a prospective single center trial to examine the rates of cancer diagnosis when using computerized software to target suspicious lesions within the prostate identified on mpMRI.
- Trial name
- NCT01964638
- Testing
- Targeted Biopsy
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- NYU Langone Health
Cervical Cancer, Anal Cancer
A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
The goal of this project is to test the efficacy of a chatbot intervention for reducing HPV vaccine hesitancy among African American parents.
- Conditions
- Cervical Cancer, Anal Cancer, Penile Cancer
- Trial name
- NCT05959564
- Testing
- Personalized Chatbot Intervention, Non-Personalized Chatbot Intervention, No Chatbot Control
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Healthy Volunteer, Prostate Cancer
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes.
- Conditions
- Healthy Volunteer, Prostate Cancer, Head and Neck Cancer, Esophageal Cancer
- Trial name
- NCT04354064
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Polycystic Ovary Syndrome (PCOS)
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women
The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS.
- Trial name
- NCT01889199
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Benign Prostatic Hyperplasia
Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes
The goal of this project is to use newly developed patient-reported outcomes to improve the clinical care of patients with benign prostatic hyperplasia.
- Trial name
- NCT05898932
- Testing
- Medical Management, Surgical Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Bladder Neoplasm, Prostate Neoplasm
Pre-Operative Single Shot Rectus Sheath Block
Objectives The primary objective is to demonstrate that in patients undergoing major urologic surgery, Patient Controlled Analgesia (PCA) opioid consumption in the first 24 hours after surgery will be significantly less in…
- Conditions
- Bladder Neoplasm, Prostate Neoplasm, Pelvic Neoplasm, Urologic Neoplasms
- Trial name
- NCT03458598
- Testing
- Rectus sheath block, Bilateral rectus sheath catheter, Patient controlled opioid analgesia (PCA)
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Alberta
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS
Benign prostatic hyperplasia (BPH) and its related symptoms are a common condition that affects nearly half of men over age 50 and 90% of men over 80.
- Trial name
- NCT01589263
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Benign Prostatic Hyperplasia, Prostatitis
2013 Annual National Digital Rectal Exam (DRE) Day Study
We aim to determine the effectiveness of 2013 "Mag paDRE ka" programme in increasing general public awareness on prostate health and promoting prostate health assessment among Filipino males aged 40 or older.
- Conditions
- Benign Prostatic Hyperplasia, Prostatitis, Prostate Cancer
- Trial name
- NCT01886547
- Testing
- Prostate health screening
- Where
- Philippines
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- St. Luke's Medical Center, Philippines
Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial
This clinical trial studies the side effects of image-guidance and online adaptation with stereotactic body radiation therapy (SBRT) for the treatment of patients with prostate adenocarcinoma that has not spread to other parts of…
- Conditions
- Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- NCT07276438
- Testing
- Biospecimen Collection, Computed Tomography, CT-guided Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Isoflavones and Radiation Therapy in Treating Patients With Localized Prostate Cancer
RATIONALE: Eating a diet high in soy foods may slow the progression of some types of cancer. Isoflavones are compounds found in soy food that may slow the growth of prostate cancer cells and prevent further development of…
- Trial name
- NCT00243048
- Testing
- soy protein isolate, radiation therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Prostatodynia
Management of Prostatodynia in Younger Patients With Non-ablative Erbium:YAG Intraurethral Laser
This prospective study aimed to compare the clinical outcomes between the use of the erbium: YAG (Er:YAG) laser, intraurethrally administered in long non-ablative SMOOTH™ train of pulses applied at the level of the male prostatic…
- Trial name
- NCT04446598
- Testing
- non-ablative SMOOTH mode Erbium YAG laser, Tadalafil 5mg
- Where
- Argentina
- Volunteers
- 36 people
- Sponsor
- Adrian Gaspar
Prostate Cancer
External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer
Primary Objective: To assess the possible improvement in prostate specific antigen (PSA) outcome of short course androgen suppression therapy in conjunction with dose-escalation intensity modulated radiation therapy (IMRT), 3D…
- Trial name
- NCT00388804
- Testing
- Radiation Therapy, Bicalutamide, Leuprolide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Clinical Evaluation of the Efficacy and Safety of a Medical Device in the Form of Rectal Suppositories (Prospidol®) for the Treatment of Symptoms Associated With Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
The goal of this clinical trial is to evaluate whether a medical device is effective and safe in treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in adult men.
- Trial name
- NCT07685847
- Testing
- Prospidol suppository
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- S&R Farmaceutici S.p.A.
Digestive System Disease, Urologic Diseases
Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
The aim of this multicenter, prospective, randomized, double-blind and large sample study is to explore the preventive effect of low-dose droperidol on POD in elderly patients after non-cardiac surgery, providing new approach for…
- Conditions
- Digestive System Disease, Urologic Diseases, Gynecological Disease, Orthopedic Surgery
- Trial name
- NCT05401058
- Testing
- Droperidol Injection, Saline
- Where
- 9 sites in China
- Volunteers
- 797 people
- Sponsor
- RenJi Hospital
Prostate Cancer
Initiation of Androgen Deprivation Therapy for Prostate Cancer Using Degarelix Followed by Leuprolide
The purpose of this study is to determine if patients initiating androgen deprivation therapy (ADT) for prostate cancer can be transitioned from degarelix acetate to leuprolide acetate after an initial three-month period without…
- Trial name
- NCT01344564
- Testing
- Degarelix acetate, Leuprolide acetate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Urology of Virginia
Varicocele, Viral Infection
The Search for Viral and Bacterial Etiology of Varicocele
This study is to answer the question is there any relationship between viral ( HSV 1 , HSV 2 , HPV 6/11, CMV, HHV 6 , HHV 8, BKV) or bacterial (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Fusobacterium…
- Conditions
- Varicocele, Viral Infection, Bacterial Infections, Sonic Hedgehog Expression
- Trial name
- ViBaVa (NCT03079609)
- Testing
- subinguinal microscopic varicocelectomy, open hernia repair
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Prostate Cancer
Randomized Phase II Study of ADT + Abiraterone vs ADT + Docetaxel + Abiraterone
This is a phase II, randomized, open label study comparing first line therapy with AThis is a phase II, randomized, open label study comparing first line therapy with ADT + abiraterone (doublet arm) or ADT + abiraterone +…
- Trial name
- NCT06060587
- Testing
- Docetaxel, ADT, Abiraterone
- Where
- United States
- Sponsor
- Northwestern University
Prostate Cancer
11C-choline PET/CT Based Helical Tomotherapy as Innovative Treratment Approach for Bone Metastases in Prostate Cancer Patients.
The number of metastases may reflect the biological aggressiveness of the tumor and may determine the possibility of performing potential curative interventions such as surgery or high-dose targeted radiotherapy (RT).
- Trial name
- NCT06179706
- Testing
- 11C-choline PET/CT
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Erectile Dysfunction
NGF, TrKA,p75NTR in Men With ED and Diabetes With or Without MS
To evaluate the level of NGF,TrKA and p75NTR in patientd with erectile dysfunction and diabetes with or without metabolic syndrome
- Trial name
- ED (NCT03862547)
- Testing
- A peripheral blood sample from the cubital vein
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University Of Perugia
Prostate Cancer, Breast Cancer Female
Molecular Imaging of Gastrin Releasing Peptide Receptors Using Labeled Technetium-99m RM26
The study should evaluate the biological distribution of 99mTc-RM26 in patients with prostate cancer and breast cancer. The primary objective are: 1.
- Trial name
- NCT04746638
- Testing
- whole body study and SPECT with 99mTc-RM26
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
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