Clinical trials: Generative Artificial Intelligence
Clinical Decision Support
Artificial Intelligence (AI)-Initiated Clinical Decision Support in Hospitalist Practice
This study will evaluate the feasibility of using artificial intelligence (AI)-generated clinical decision support during routine inpatient hospital medicine care.
- Trial name
- NCT07889063
- Testing
- AI Clinical Decision Support: Automated EHR Data Retrieval, AI Clinical Decision Support: Admission H&P Note
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Study Aims to Develop and Validate a Generative AI-assistant Designed to Optimize Radiologists' Workflows and to Evaluate Its Performance
Generative AI Radiologist's Workstation
This study aims to develop a generative AI assistant for radiologists to automate the processing of electronic medical records (EMRs) and provide relevant clinical information, optimizing diagnostic interpretation workflows.
- Trial name
- GARW (NCT07057830)
- Where
- 2 sites in Russia
- Volunteers
- 27 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Medical Education
AI-Generated and Rule-Based Individualized Feedback for Medical Students' Nephrology Learning
Medical education increasingly emphasizes individualized learning and formative assessment; however, providing timely and personalized feedback to students remains challenging because of limited faculty resources.
- Trial name
- AIFB-NR (NCT07871526)
- Testing
- AI-Generated Individualized Feedback, Rule-Based Individualized Feedback, No Individualized Feedback
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Dou Fulin
Physical Activity
Self-directed Use of Resources for Physical Activity
This is a pilot RCT examining physical activity outcomes at 3 months across 3 conditions: use of large language model (LLM) fully self-directed; use of LLM with guidance; and use of online tools to help with sleep.
- Trial name
- CHARGE (NCT07654868)
- Testing
- LLM alone, LLM enhanced, Sleep promotion
- Volunteers
- 39 people
- Sponsor
- University of Florida
Anterior Segment Diseases
Multimodal Deep Learning Model for Multi-task Diagnosis and Triage Suggestions of Ophthalmic Diseases
Accurate and comprehensive interpretation of anterior segment diseases from slit-lamp and smartphone photographs remains a clinical challenge due to the limited specificity and structure of existing Artificial Intelligence tools.
- Trial name
- NCT07447973
- Testing
- Multimodal Vision-language Model Diagnosis
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Artificial Intelligence (AI), Clinical Reasoning
Teaching Doctors in Training to Reason With Artificial Intelligence
The purpose of the TEACH-AI study is to assess whether a brief, structured workshop on artificial intelligence can improve the performance of medicine doctors in training (i.e.
- Conditions
- Artificial Intelligence (AI), Clinical Reasoning, Clinical Decision-making, Medical Education
- Trial name
- TEACH-AI (NCT07813754)
- Testing
- Workshop-First
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Primary Care Patients
AI to Create Accessible & Reliable Patient Education Materials
This study investigates the use of Generative AI (GAI) to support primary care practices in delivering accurate, accessible patient education.
- Trial name
- AI-CARE (NCT06997107)
- Testing
- Health promotional messages generated by Artificial Intelligence, Health promotional messages generated by humans
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Cannabis Use Disorder, Anxiety
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression.
- Conditions
- Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT06920238
- Testing
- Therabot-CALM
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Trustees of Dartmouth College
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Clinical Reasoning in Nursing Education, Virtual Simulation
MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training
This study compares the effectiveness of a Generative AI-integrated blended simulation programme and high-fidelity simulation alone on nursing students' clinical reasoning and learning experience during deterioration training
- Conditions
- Clinical Reasoning in Nursing Education, Virtual Simulation, Artificial Intelligence in Education, Deterioration, Clinical
- Trial name
- MAGICS (NCT07872735)
- Testing
- Generative AI-integrated Blended Simulation, High Fidelity Simulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Generative Artificial Intelligence
Implementation of a Blended Online and Offline Teaching Model
This study aims to design, implement, and evaluate a blended online and offline teaching model for Internal Medicine Nursing, integrating generative artificial intelligence (GAI), a virtual simulation platform, card-based…
- Trial name
- NCT07189611
- Testing
- A blended online and offline teaching model for internal medicine nursing practice based on generative artificial intelligence
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hengxu Wang
Rheumatoid Arthritis (RA, Osteoporosis
Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis
Generative AI (GenAI) based on large language models (LLMs) is expected to improve the diagnosis and treatment of autoimmune diseases.
- Conditions
- Rheumatoid Arthritis (RA, Osteoporosis, Osteoarthritis, Interstitial Lung Disease
- Trial name
- NCT07301892
- Testing
- Generative AI prediction report for RA complications
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Prostate Cancer (Adenocarcinoma), Bladder Cancer
Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3)
This trial tests if AI can help make medical info clear and readable. Many patients struggle to find medical informations that easy to read and understand from verified medical sources.
- Conditions
- Prostate Cancer (Adenocarcinoma), Bladder Cancer, Kidney Cancers, Testis Cancer
- Trial name
- NCT07568444
- Testing
- Pub2Post
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Lymphoma, Multiple Myeloma
An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers
The goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments)…
- Trial name
- NCT07226934
- Testing
- GPT-QPL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Breast Cancer, Metastatic Breast Cancer
Generative AI Patient Education Module for Breast Oncology
This study evaluates the safety, accuracy, and impact of an artificial intelligence (AI) tool designed to support patient education in breast cancer care for breast oncology patients under selected physicians care within the…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Carcinoma of the Breast
- Trial name
- NCT07512271
- Testing
- Survey (Participant), OpenEvidence CareConnect, Survey (Provider)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Health Communication, Patient Discharge
AI-Assisted Discharge Documents for Children and Families in a Pediatric Emergency Department
This study compared two ways of preparing discharge documents for children and families leaving a pediatric emergency department.
- Trial name
- EA (NCT07874659)
- Testing
- Conventional Discharge Documentation Workflow, LLM-Assisted Discharge Documentation Workflow
- Where
- 2 sites in France
- Volunteers
- 153 people
- Sponsor
- University Hospital, Montpellier
Clinical Competence, Communication Skills
Generative AI Simulated Patients Versus Expert Demonstration Videos for Psychiatric Interview Training in Occupational Therapy Students
The goal of this study is to compare two methods for teaching psychiatric work-history interviewing to third-year occupational therapy students: practice with a generative AI simulated patient and an expert demonstration video.
- Conditions
- Clinical Competence, Communication Skills, Self Efficacy
- Trial name
- NCT07896525
- Testing
- Generative AI simulated patient, Expert demonstration video
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Nursing Education, Simulation-Based Learning
Effects of Concept Mapping and AI Dialogue on Flow and Learning Outcomes in Simulation-Based Learning
This mixed-methods educational study evaluates the integration of concept mapping and artificial intelligence (AI)-supported dialogue into simulation-based learning for nursing students.
- Trial name
- NCT07748897
- Testing
- ChatGPT-Assisted Preparation for Pediatric Nursing Simulation, Standard Preparation for Pediatric Nursing Simulation
- Where
- Taiwan
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Generalized Anxiety, Fear of Failure
Optimization of Late Imagery Rescripting Research Using Generative Artificial Intelligence
The aim of the study is to examine the effect of imagery rescripting (ImRs) in the context of utilizing large language models (LLMs).
- Conditions
- Generalized Anxiety, Fear of Failure, Rumination
- Trial name
- ImRs_LLM_DeanG (NCT07565714)
- Testing
- Imagery Rescripting Intervention
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Atrial Fibrillation (AF)
Patient Perceived Empathy of an AI Chatbot for Atrial Fibrillation Education
Atrial Fibrillation is a chronic disease with significant health consequences like increased risk of stroke, heart failure, heart attack and death.
- Trial name
- NCT06684457
- Testing
- Atrial Fibrillation Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh