Clinical trials: Generalised Anxiety Disorder
Positive Emotions, Mental Health
Reducing Symptoms of Depression, Stress and Anxiety and Enhancing Positive Mental Health: a Randomized-controlled Study of the Positive Emotions Training
Based on the results of the previously published paper "Positive Emotions Training (PoET) as an online intervention to improve mental health: a feasibility study" (Niemann et al., 2023) the goal of this study was to examine the…
- Conditions
- Positive Emotions, Mental Health, Intervention (Training) Condition, Randomized Controlled Study
- Trial name
- NCT06851637
- Testing
- PoET
- Where
- Germany
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Generalized Anxiety Disorder
CBT for GAD: Impact of Cognitive Processing on Treatment Outcome
Generalized anxiety disorder (GAD) is a condition characterized by chronic and excessive worry and anxiety. Over the past 15 years, the investigators have developed a cognitive-behavioural treatment that leads to the remission of…
- Trial name
- NCT03099772
- Testing
- CBT-IU
- Volunteers
- 80 people
- Sponsor
- Concordia University, Montreal
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Generalized Anxiety Disorder
A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)
A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Generalized Anxiety Disorder - Voyage
- Trial name
- NCT06741228
- Testing
- DT120
- Where
- 34 sites in United States
- Volunteers
- 214 people
- Sponsor
- Definium Therapeutics US, Inc.
Generalized Anxiety Disorder
A Pilot Study of Cranial Electrotherapy Stimulation[CES] for Generalized Anxiety Disorder
Cranial electrotherapy stimulation(CES) is a noninvasive procedure that has been used for decades in the United States to treat anxiety, depression, and insomnia in the general population.
- Trial name
- NCT00539357
- Testing
- Cranial electrotherapy stimulation (CES)
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
Generalized Anxiety Disorder
A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs Alone
Generalized anxiety disorder (GAD) is usually treated with antidepressant therapy (ADT); however, sometimes ADTs alone are not enough to adequately treat GAD.
- Trial name
- CAR aGAD Ph 2 (NCT04965272)
- Testing
- Cariprazine 0.75 mg/day, Cariprazine 1.5 mg/day, Cariprazine 3.0 mg/day
- Where
- 36 sites in United States
- Sponsor
- AbbVie
Herniated Intervertebral Disc
Artificial Intelligence Assisted Spine Rehabilitation in Cervical Disc Herniation
The aim of this study is to investigate the effect of artificial intelligence-assisted spinal rehabilitation in neck hernia compared to traditional methods.
- Trial name
- NCT06632028
- Testing
- artificial intelligence assisted spinal rehabilitation, conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Okan University
Generalized Anxiety Disorder
Digital Interventions As an Add-on Tool in Generalized Anxiety Disorder Treatment
Background: Over the last several years, there has been an increase in the popularity and availability of mobile digital technologies.
- Trial name
- NCT05375851
- Testing
- Digital Interventions, Treatment as Usual
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Generalized Anxiety Disorder, Social Anxiety Disorder
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 75 participants with clinical anxiety and…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03899090
- Testing
- Float pool, Float chair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Generalized Anxiety Disorder
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study
The purpose of this research is to look at the effects of computerized cognitive training on anxiety, sleep, mental abilities (cognition), and other aspects of daytime functioning, such as arousal.
- Trial name
- COGMA (NCT04421690)
- Testing
- Cognitive Training, Trivia Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Anxiety Disorder (Panic Disorder or GAD), Anxiety Symptoms
Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.
Anxiety is one of the most frequent disorders during the perinatal stage which is associated with adverse health effects for women and their babies. In spite of this, preventive interventions during this stage are scarce.
- Trial name
- NCT06609291
- Testing
- Telematic Prenatal Psychological Intervention for Preventing Anxious Symptomatology
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Anxiety
the Activating Consciousness Technique (Hypnosis) in General Practice
Anxiety is an emotion considered unpleasant but resulting from a normal phenomenon. It corresponds to an adaptive response to events, to stress and helps to ensure our survival.
- Trial name
- MG HYPNOSIS (NCT04649762)
- Testing
- activating consciousness technique (hypnosis)
- Where
- 6 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Generalized Anxiety Disorder
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, phase 3, randomized, double-blind, parallel-group, 2-arm, placebo controlled, multicenter trial designed to compare the efficacy, safety and tolerability of a fixed dose of SEP-363856 (75 millligrams per day…
- Trial name
- NCT07767903
- Testing
- SEP-363856
- Where
- 11 sites in United States
- Volunteers
- 384 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Specific Phobia, Separation Anxiety
Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical Setting
An open trial will be conducted at the Child and Mental Health Service (CAMHS) unit in the rural county Jämtland in Sweden to test the feasibility and efficacy of Internet-delivered Cognitive Behavior Therapy (ICBT) for children…
- Conditions
- Specific Phobia, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT02306356
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Anxiety Disorders
Treatment for Anxiety in Children
The purpose of this study is to see if it is effective to treat children with anxiety disorders with fluvoxamine. Fluvoxamine has been successfully used to treat obsessive-compulsive disorder (OCD) in adults and children.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT00000389
- Testing
- Fluvoxamine
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder
Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD
Meta Cognitive Therapy (MCT) has been introduced as a new specific treatment for generalised anxiety disorder. So far, no studies have examined CBT and MCT in comparison with each other in a randomised controlled trial.
- Trial name
- NCT00426426
- Testing
- Cognitive-Behavioural Therapy, Meta-Cognitive Therapy, Waiting list
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Generalized Anxiety Disorder
6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)
This is an open-label, multi-site, 6-month study of an investigational compound in elderly outpatients, age 65 years old or above, to assess the long-term safety and tolerability of the compound in the treatment of elderly…
- Trial name
- NCT00738738
- Testing
- PD-0332334
- Where
- 2 sites in United States
- Sponsor
- Pfizer
Generalized Anxiety Disorder, Oxygenation Sensitive CMR
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
This study aims to view variations in MRI measurements of the heart and the brain in people with anxiety versus healthy volunteers.
- Trial name
- B-GLAD (NCT05574140)
- Testing
- Cardiac MRI
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anxiety Disorders
Study to Assess the Efficacy and Safety of Levetiracetam for the Treatment of Social Anxiety Disorder (Generalized Type)
Preclinical and clinical findings indicate that LEV has some anxiolytic potential. There is reason to believe that compounds with anxiolytic activity may have broad clinical utility across the anxiety spectrum.
- Trial name
- NCT00612859
- Testing
- levetiracetam
- Volunteers
- 217 people
- Sponsor
- UCB Pharma
Anxiety Disorders
Fixed Dose Study of PD 0332334 and Paroxetine for the Treatment of Generalized Anxiety Disorder
This study is a randomized, double-blind, parallel-group, multi-site, Phase 3, placebo controlled fixed-dose study of PD 0332334 and paroxetine in 528 outpatients with generalized anxiety disorder.
- Trial name
- NCT00836069
- Testing
- No drug name provided by Sponsor; drug referenced as PD 0332334, Paroxetine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Cedars-Sinai Medical Center