Clinical trials: General Surgery
Obesity, Bariatric Surgery Candidate
Transition of Single Surgeon Bariatric Service to an Interdisciplinary Multiple Surgeon Model
This retrospective study will analyse the transition of an Australian hospital which significantly increased volume of bariatric operations after introduction of a clinical pathway, and to assess the outcomes.
- Trial name
- NCT04431583
- Testing
- Bariatric surgery- single surgeon service, Bariatric surgery- multiple surgeon + multidisciplinary team approach, Bariatric surgery: formalized streamlined multiple surgeon + multidisciplinary team approach
- Volunteers
- 146 people
- Sponsor
- University of Adelaide
Glaucoma, Optic Neuropathy
Use of Bevacizumab in Trabeculectomy Surgery
When a patient with glaucoma who has a pressure that is too high and causing damage to their vision, despite receiving the maximum amount of medication that can be tolerated, the decision is made to have glaucoma surgery.
- Conditions
- Glaucoma, Optic Neuropathy, Fibrosis
- Trial name
- NCT01166594
- Testing
- Bevacizumab, Control
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anxiety State, Pain
The Effect of Music and White Noise on Patients' Anxiety and Pain During Surgery for Impacted Mandibular Third Molar
The goal of this clinical trial is to evaluate the effect of music and whitenoise on the anxiety and pain level of patients who had impacted third molars surgery.
- Trial name
- NCT06814366
- Testing
- music and white noise intervention, music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
VATS, Kinesiophobia
Comparison of Early Postoperative Functional Capacity and Kinesiophobia in Patients Undergoing Thoracic Surgery Via Thoracotomy or VATS
This observational cross-sectional study aims to compare early postoperative functional capacity and kinesiophobia in patients undergoing thoracic surgery via thoracotomy or video-assisted thoracic surgery (VATS).
- Conditions
- VATS, Kinesiophobia, Thoracotomy, Thoracic Surgery
- Trial name
- NCT07647822
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
Ovary Cancer
An Exploratory Study of the Folic Acid-tubulysin Conjugate EC1456 in Ovarian Cancer Subjects Undergoing Surgery
This study looks to enroll subjects with ovarian cancer who will be having standard of care surgery to remove ovarian cancer tumors.
- Trial name
- NCT03011320
- Testing
- EC1456, 99mTc-Etarfolatide
- Where
- 2 sites in United States, Canada
- Volunteers
- 3 people
- Sponsor
- Endocyte
Cardiovascular Surgical Procedures, Intensive Care
Energy Expenditure Estimation in Cardiac Surgery
Estimation of energy requirements is essential for adequate nutritional support in ICU. Indirect calorimetry being the golden standard of resting energy expenditure estimation is not available in most intensive care units.
- Trial name
- NCT02463123
- Testing
- Indirect calorimetry
- Where
- Russia
- Volunteers
- 240 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Assessing Myocardial Blood Flow and Blood Flow Reserve by Transoesophageal Echocardiography (TEE)
Until today it was not possible to reliably assess the function of a new bypass, i.e., to measure myocardial perfusion. Measuring intramyocardial blood flow directly after revascularisation would greatly improve the assessment of…
- Trial name
- NCT00286559
- Testing
- SonoVue, Optison
- Sponsor
- University Hospital, Basel, Switzerland
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Inguinal Hernia, Surgery
Analgesia Evaluation of an Ultrasound-guided Technique for Inguinal Hernia Surgery in Children in Children
The basis for the transversalis fascia plane (TFP) block involves infiltration of local anaesthetic blocking the ilioinguinal and iliohypogastric nerve which are located between the fascia of the transversus abdominis muscle and…
- Conditions
- Inguinal Hernia, Surgery, Paediatric
- Trial name
- NCT06883370
- Testing
- ultrasound-guided transversals fascia plane block with ropivacaine
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Surgical Site Infections
Effect of Mupirocin Dressings Versus Island Dressings on Surgical Site Infections in Elective Colorectal Surgery
Infections at the site of surgical incisions (SSIs) are the most common infection among surgical patients. Although all patients undergoing surgical procedures are at risk for developing SSIs, colorectal surgery has had…
- Trial name
- NCT02619773
- Testing
- mupirocin ointment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Spine Condition
Evaluating MIONM Effectiveness in Predicting Postoperative Neurological Deficits Using Combined Modalities
Objective: This study aimed to integrate findings from spinal and cranial surgeries with existing literature, emphasizing the role of Intraoperative Neurophysiological Monitoring (IONM) in improving surgical outcomes through best…
- Trial name
- MIONM (NCT06712069)
- Testing
- Multimodal Intraoperative Neurophysiologic Monitoring (MIONM)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Rectal Adenoma
Efficiency of Two Dimensional High Definition vs Three Dimensional Endoscopic Systems in Transanal Endoscopic Surgery
Introduction: The usual surgical technique for large adenomatous tumors and rectal cancer is anterior resection of the rectum or abdominoperineal resection.
- Trial name
- NCT01498354
- Testing
- 2-D high definition vision systems, transanal endoscopic operation (TEO), Transanal endoscopic microsurgery (TEM)
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Corporacion Parc Tauli
Liver Cancer
Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
RATIONALE: Sirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways.
- Trial name
- NCT00467194
- Testing
- Rapamycin, Bevacizumab
- Where
- 2 sites in Singapore
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Cancer, Surgery
The ICALIC 2 International Multicentric Study
Clinicians need to measure energy expenditure (EE) by indirect calorimetry (IC) to optimize nutritional support for a better clinical outcome, especially in patients with chronic conditions or with high risk of under- and over…
- Conditions
- Cancer, Surgery, Hemodialysis
- Trial name
- ICALIC2 (NCT03947294)
- Testing
- Q-NRG®
- Where
- Switzerland
- Volunteers
- 137 people
- Sponsor
- Prof. Claude Pichard
Coronary Arteriosclerosis
Epicardial Echocardiography of Coronary Anastomoses Using the Echoclip Device
The aim of this study is to evaluate whether use of the echoclip device (an ultrasound transducer positioning device which can stabilize the involved part of the myocardium on the beating heart) facilitates imaging of coronary…
- Trial name
- NCT02919124
- Testing
- Echoclip
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Aalborg University Hospital
Carpal Tunnel Syndrome
A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist.
- Trial name
- NCT07312123
- Testing
- Alpha-Lipoic Acid, Vitamin E, and Vitamin B Complex, Combination Vitamin B1,B6,B12
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- Hospital Universiti Sains Malaysia
Hypervolemia, Hypovolemia
Effects of Different Fluid Transfusion Regimens On Glycocalyx In Patients Undergoing Thoracic Surgery.
Introduction: Endothelial Glycocalyx (EG) composing of proteoglycans heparan sulfate (HS), syndecan, and plasma proteins forms a physiologically active surface layer on the vascular endothelium, regulates oncotic pressure.
- Trial name
- NCT07192523
- Testing
- Restrictive fluid therapy, Liberal fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Breast Cancers
Partial Breast Re-irradiation for Breast Cancer
Breast cancer is the most common malignancy in women. Breast-conserving surgery (BCS) with adjuvant whole-breast irradiation (WBI) is currently the standard of care in the oncological treatment of primary breast cancer and offers…
- Trial name
- BREAST (NCT06954623)
- Testing
- Radiation Therapy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Cervical Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
- Trial name
- ROCC (NCT04831580)
- Testing
- da Vinci, open surgery
- Where
- 156 sites in United States, Brazil and 2 more
- Volunteers
- 840 people
- Sponsor
- GOG Foundation