Clinical trials: General Anesthesia
Cesarean Section
Presence of the Father During Hyperacute Cesarean Section in General Anesthesia
This study concerns cesarean sections, category 1, meaning those cases where the life of mother and/or fetus is in immedeate danger and the child must be delivered within 15 minutes from activating the cesarean section team.
- Trial name
- NCT04948892
- Testing
- Prescence of the father during cesarean section in general anesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 26 people
- Sponsor
- Sygehus Lillebaelt
Postoperative Complications, Postoperative Pain
Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal Mask
The purpose of this study is to evaluate gender specific risk factors and the influence of cuff pressure in the occurrence of postoperative sore throat and hoarseness following general anaesthesia using Ambu® AuraGain™ Laryngeal…
- Trial name
- LadyLAMA (NCT04915534)
- Testing
- Ambu® AuraGain™ Laryngeal Mask (LM)
- Where
- Germany
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Desaturation of Blood, Anesthesia
Early Warning for Desaturation by Oxygen Reserve Index
During the induction of general anesthesia, the anesthesiologist needs to provide the oxygen supply to meet the patient's needs continuously.
- Trial name
- NCT04976504
- Testing
- Oxygen reserve index
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Regional Anesthesia, Heart Surgery
Nociception-directed Erector Muscle Spinae Plane Block in Open Heart Surgery
With the advent of ultrasound (US) guidance, use of regional anaesthesia (RA) is poised to grow and evolve. Recently, cardiac surgery has benefited from newer US guided interfascial techniques as they promise to fulfil all the…
- Trial name
- NESP (NCT04338984)
- Testing
- General anesthetic, Ropivacaine 0.5% Injectable Solution
- Where
- Romania
- Volunteers
- 86 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Anesthesia
Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth
Minimal flow anesthesia has economic and environmental advantages in addition to providing earlier recovery following general anesthesia.
- Trial name
- NCT05024084
- Testing
- Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Sevoflurane, Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ufuk University
General Anesthesia, Elective Surgery
Therapeutic Equivalence (TE) Study of Propofol 2% MCT Fresenius (MCT=Medium-Chain Triglycerides) Compared With Diprivan® in Patients Undergoing Elective Surgery
The purpose of this study is to evaluate the therapeutic equivalence, based on pharmacodynamic parameters of Propofol 2% (20 mg/mL) MCT Fresenius and Diprivan® 20 mg/mL (AstraZeneca), administered by target controlled infusion…
- Trial name
- PropofolTE (NCT01856998)
- Testing
- Propofol, Diprivan
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Fresenius Kabi
Lung Cancer, Neoplasms, Lung
Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia
The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.
- Trial name
- NCT00935571
- Testing
- propofol, remifentanil, sevoflurane
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Asan Medical Center
Postoperative Nausea
Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia
The purpose of this study is to determine if intravenous fosaprepitant can interfere with nervous system monitoring signals in patients having surgery under general anesthesia.
- Trial name
- NCT03197064
- Testing
- Fosaprepitant 150 mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
General Anesthesia, Thoracic Epidural Anesthesia
Postoperative Sleep Quality in Patients Undergoing Thoracic Surgery With Different Types of Anesthesia Management
We designed a study to determine whether a single dose of dexmedetomidine or thoracic epidural anesthesia combined with general anesthesia would provide hemodynamic stability, reduce stress hormone responses, inhibit inflammatory…
- Trial name
- NCT01725607
- Testing
- general anesthesia combined with dexmedetomidine infusion, general anesthesia combined with TEA
- Where
- China
- Volunteers
- 219 people
- Sponsor
- China Medical University, China
Anesthesia, General
Assessing Pain in the Postoperative Period by Automatically Measuring the Variation Coefficient of Pupillary Diameter: PREVANS Study
Different pain assessment methods have been proposed to evaluate analgesic efficacy after surgical operation. Pain is a subjective phenomenon. Patient did his pain self assessment.
- Trial name
- PREVANS (NCT03267979)
- Testing
- Video-pupillometer, Electrocardiogram
- Where
- France
- Volunteers
- 345 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Orthopedic/Podiatry Procedures
Effects of Dexmedetomidine on Tourniquet Pain Associated With Lower Extremity Surgeries Under General Anesthesia
This study is being done to determine if the drug known as dexmedetomidine improves the way we care for patients when their surgery involves the use of a tourniquet on the leg.
- Trial name
- NCT00932386
- Testing
- Dexmedetomidine Hcl infusion, normal saline
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Complications
Open Lung Approach During General Anaesthesia to Prevent Post-Operative Pulmonary Complications
The hypothesis of this study is that the "Open lung approach" ( recruitment and PEEP) during general anaesthesia reduces atelectasis formation and improves respiratory function in the immediate post-operative period after major…
- Trial name
- NCT00426790
- Testing
- Positive end-expiratory pressure
- Where
- Italy
- Sponsor
- Università degli Studi dell'Insubria
General Anaesthesia, Depth of Anaesthesia
Epileptiform EEG Patterns During Induction of General Anaesthesia With Sevoflurane Compared to Those With Propofol
The aim of the study was to assess the influence of volatile induction of general anaesthesia with sevoflurane using two different techniques and intravenous anaesthesia with propofol on the possible presence of epileptiform…
- Conditions
- General Anaesthesia, Depth of Anaesthesia, Intraoperative Awareness, Seizures
- Trial name
- EEG (NCT03209323)
- Testing
- electroencephalography (EEG), bispectral index (BIS), response and state entropy (RE and SE)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Entropy Device and How Will Muscle Relaxants Affect it
Impact of Entropy Monitoring on Anesthetic Consumption and Recovery After Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if brainwave-guided anesthesia (entropy monitoring) can reduce anesthetic drug consumption and speed up recovery time in adult patients undergoing elective laparoscopic cholecystectomy…
- Trial name
- NCT07847788
- Testing
- Entropy Monitoring-Guided Anesthesia Titration, Standard Clinical Parameter-Guided Anesthesia Titration
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- KRL Hospital, Islamabad
Preoperative Anxiety
Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery
Preoperative anxiety is a common issue in pediatric anesthesia. Children often experience anxiety and uneasiness due to uncertain outcomes.
- Trial name
- NCT06489327
- Testing
- melatonin (Circadin ®) 0.2 mg/kg, melatonin (Circadin ®) 0.4 mg/kg
- Where
- 2 sites in Egypt, Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Intubation Complication
Assessment of a Properly Video Stylet Angulation for Nasotracheal Intubation
Uses the video stylet with different angulation to assist the nasotracheal tube passing the nasal cavity, oropharynx and advanced into the trachea.
- Trial name
- NCT04749225
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain, Postoperative, Postoperative Complications
Open and Laparoscopic Total Extraperitoneal Repair Under Spinal Anesthesia Versus General Anesthesia
Inguinal hernia surgery is one of the most frequently performed procedures among general surgery cases. As with many open surgical methods, this repair is also performed laparoscopically.
- Conditions
- Pain, Postoperative, Postoperative Complications, Inguinal Hernia
- Trial name
- NCT05837013
- Testing
- Spinal anesthesia (with nerve block), General anesthesia (GA)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Konya City Hospital
Hip Arthropathy, Hip Disease
Cardiac Index and General Anesthesia Without Opioid.
General anesthesia used to be based on the association of hypnotics and opioid drugs. But recent studies showed that opioids may be related to a many different complications, like respiratory distress, hyperalgesia.
- Trial name
- OFFLOW (NCT05446623)
- Testing
- Dexmedetomidine, Sufentanil
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Montauban
Temperature, General Anesthesia
Correlation Between Core Temperature and Skin Temperature Measured by 3M SpotOn
Core temperature should be monitored under general anesthesia. Recently developed 3M Spoton skin temeprature which is applied on temporal artery is correlated with core temperature measure by esophageal prove in several studies.
- Trial name
- Temperature (NCT03745079)
- Testing
- Esophagus temperature monitoring, Spoton Temporal, Spoton Carotid
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Ajou University School of Medicine