Clinical trials: General Anaesthesia
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Apneic Oxygenation
Flow Rate Impact on Arterial Carbon Dioxide During THRIVE
Apneic oxygenation describes the process of continuous oxygenation of the blood without breathing efforts. This anesthesia technique has been described in the literature for more than 100 years and is sometimes used under general…
- Trial name
- ThriVent (NCT05234424)
- Testing
- THRIVE
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Uppsala University Hospital
General Anesthesia
Relationship Between the Depth of Anesthesia and Auditory Evoked Potentials (P3a)
The interest of perioperative cerebral monitoring and in particular electroencephalography (EEG) to reduce neurological and cognitive damage in surgery has been the subject of abundant research and corresponds to a crucial issue.
- Trial name
- MP3 (NCT05283018)
- Testing
- Electroencephalogram recording, Auditory stimulation, Transcranial Doppler
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intraoperative Analgesia
NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia
The aim of this study is to investigate the hypothesis that the intraoperative use of the nociception level index NOL can reduce opioid consumption in adult patients undergoing elective laparoscopic surgeries under general…
- Trial name
- NOLGADELS (NCT06104059)
- Testing
- Nociception level index (NOL™), Fentanyl
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Attikon Hospital
Coronary Syndrome, Pediatric
Cerebral Oxygenation and Burst Suppression
investigators want to observe a group of pediatric patients who are going to undergo open thoracic surgery at Queen Silvia's child and youth hospital, Sahlgrenska University Hospital.
- Trial name
- NCT04206683
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Göteborg University
Postoperative Sleep Disturbance
Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance
The goal of this clinical trial is to learn about the effect of preoperative nasal spry with dexmedetomidine on postoperative sleep disturbance in young to middle-aged women undergoing hysteroscopy.
- Trial name
- NCT06281561
- Testing
- Normal Saline, Dexmedetomidine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Phrenic Nerve Paralysis
the Clinicaltrail of the Effection Which of Phrenic Block Using in Non-intubated Video-assisted Thoracoscopic Surgery
Putting 80 patients divided into group S（non-intubated general anesthesia combine with Paravertebral blocks、surface spray anesthesia and Vagus block） and group D（non-intubated general anesthesia combine with Paravertebral…
- Trial name
- NCT03653494
- Testing
- phrenic block, no phrenic block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shenzhen People's Hospital
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital
Adult, Anesthesia, General
Anesthesia Induction With Intravenous Bolus or Continuous Infusion of Remimazolam
Bolus injection and continuous infusion are two widely used methods for intravenous administration of drugs. Bolus injection possibly leads to a rather high drug plasma concentration temporarily, however, it can induce a rapid…
- Trial name
- NCT05423080
- Testing
- Bolus injection of remimazolam, Infusion of remimazolam
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Korea University Guro Hospital
Awakening, Post-Anesthesia Delayed
Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.
The introduction of the laparoscopic technique for cholecystectomy significantly reduced the incidence and intensity of postoperative pain, with improvement in other markers, such as patient satisfaction, and reduction in…
- Trial name
- NCT04360473
- Testing
- General anesthesia, Ketamine plus general anesthesia, Magnesium sulfate plus general anesthesia
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo General Hospital
Quality of Postoperative Recovery
Efficacy of Esketamine Combined With Different General Anesthetics on Quality of Postoperative Recovery
To explore the effect of subanesthetic-dose esketamine combined with different general anesthetic drugs on the quality of postoperative recovery in patients undergoing painless gastrointestinal endoscopy.
- Trial name
- NCT06976996
- Testing
- normal saline, esketamine, propofol
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Northern Jiangsu People's Hospital
Orthopedic/Podiatry Procedures
Effects of Dexmedetomidine on Tourniquet Pain Associated With Lower Extremity Surgeries Under General Anesthesia
This study is being done to determine if the drug known as dexmedetomidine improves the way we care for patients when their surgery involves the use of a tourniquet on the leg.
- Trial name
- NCT00932386
- Testing
- Dexmedetomidine Hcl infusion, normal saline
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Vocal Cord Polyp
The Study of Bilateral Upper Laryngeal Nerve Block for Supporting the Removal of Vocal Cord Polyps Under Laryngoscopy
With the continuous development of microsurgery, supporting laryngoscopy acoustic polyp removal has become a very mature clinical operation.
- Trial name
- NCT05309174
- Testing
- USG-guided iSLN block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guizhou Provincial People's Hospital
Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Ketamine Infusions for PTSD and Treatment-Resistant Depression
The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning.
- Trial name
- NCT02577250
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Cut Flexor Hand, Walant
Compare the Outcomes of Zone II Flexor Tendon Repair of the Hand Under General Anesthesia Versus WALANT
Comparison between results of repair of cut flexor zone II under General anesthesia and Walant
- Conditions
- Cut Flexor Hand, Walant, General Anesthesia
- Trial name
- NCT04089124
- Testing
- surgery of zone II cut flexor repair
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Adductor Canal Block
Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia
Pain after anterior cruciate ligament reconstruction with autologous hamstring graft can be attributed to both arthroscopic surgery and the graft donor site.
- Trial name
- NCT06398717
- Testing
- adductor canal block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Complications
Open Lung Approach During General Anaesthesia to Prevent Post-Operative Pulmonary Complications
The hypothesis of this study is that the "Open lung approach" ( recruitment and PEEP) during general anaesthesia reduces atelectasis formation and improves respiratory function in the immediate post-operative period after major…
- Trial name
- NCT00426790
- Testing
- Positive end-expiratory pressure
- Where
- Italy
- Sponsor
- Università degli Studi dell'Insubria
Anesthesia
Prediction of Hemodynamic Reactivity During General Anesthesia Using Analgesia/Nociception Index (ANI)
The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing ear-nose-throat or lower limb orthopedic surgery on…
- Trial name
- NCT01839513
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital Edouard Herriot
Central Venous Oxygen Saturation
Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia
After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory…
- Trial name
- NCT04017182
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Ramathibodi Hospital
Immediate Severe Postoperative Pain, Perioperative Hemodynamic
GOAL-Directed ANalgesia (GOALDAN)
The primary purpose of GOALDAN study is to demonstrate the superiority of a targeted perioperative analgesic strategy by the ANI over the usual practice on the incidence of immediate postoperative pain.
- Trial name
- GOALDAN (NCT03618082)
- Testing
- Anesthesic agent guided by ANI (Interventional Group), Administration of the lowest effective concentration of desflurane (Interventional Group)
- Where
- France
- Volunteers
- 380 people
- Sponsor
- University Hospital, Clermont-Ferrand