Clinical trials: Gender Incongruence
Transgenderism, Gender Dysphoria
Effectiveness of Speech Therapy in Trans Women.
One of the greatest hurdles in the transition of transgender persons is that voice, speech and communication are not congruent with the desired gender.
- Conditions
- Transgenderism, Gender Dysphoria, Speech Therapy, Voice Disorder Due to Transsexualism
- Trial name
- NCT04708600
- Testing
- Pitch Elevation Therapy, Articulation Resonance Therapy
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Ghent
Gender Dysphoria, Emotion Regulation
Internet-delivered Treatment for Transgender Individuals With Co-occurring Mental Health Problems
This project aims to develop and evaluate if an internet delivered psychological intervention for transgender individuals undergoing assessment for gender dysphoria and a support person, is feasible, acceptable and effective in…
- Conditions
- Gender Dysphoria, Emotion Regulation, Internet Delivered Treatment
- Trial name
- IERGD (NCT05534763)
- Testing
- IERGD, IER SUPPORT
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Transgender, Gender Incongruence
The Effect of Tucking on Semen Quality of Adult Trans Women
Because gender-affirming hormone therapy (GAHT) can lead to fertility impairment, current guidelines and treatment recommendations require that patients be informed about the possibility of fertility preservation prior to…
- Conditions
- Transgender, Gender Incongruence, Fertility Issues
- Trial name
- NCT06530992
- Testing
- tucking break
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Gender Incongruence, Transgenderism
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
The purpose of this research is to find out if hormone therapy in transgender subjects' changes hormone receptors in blood, muscle and fat; fat production; muscle production; and inflammation processes.
- Trial name
- NCT04551144
- Testing
- testosterone cypionate, Estradiol Valerate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- St. Louis University
Gender Incongruence, Cardiovascular Disease (CVD) Risk Factors
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy
Gender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the…
- Trial name
- CARMEN (NCT07128771)
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Gender Dysphoria, Adult
GLOW: Gender-Affirming Care and Mental Health: A Longitudinal Study On Quality of Life, Work Life, and Healthcare Outcomes
Gender-Affirming Care and Mental Health (GLOW) investigates the psychological, medical, and social factors that influence the outcomes of gender-affirming care, as well as its impact on mental health, work capacity, and quality…
- Trial name
- GLOW (NCT07480590)
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Region Skane
Transgenderism, Gender Dysphoria
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
- Conditions
- Transgenderism, Gender Dysphoria, Insulin Sensitivity
- Trial name
- PUBERTY (NCT04596592)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Gender Dysphoria in Children, Puberty
Skeletal Health and Bone Marrow Composition Among Youth
Children and adolescents experiencing gender dysphoria feel increased distress with the onset of puberty. Gender clinics treat these young adolescents by "blocking" puberty using gonadotropin-releasing hormone (GnRH) agonist…
- Conditions
- Gender Dysphoria in Children, Puberty, Bone Development
- Trial name
- NCT04203381
- Testing
- GnRH Agonist
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Amy DiVasta, MD
Gender Dysphoria
Polyethylene-glycol Assisted Nerve Repair in Phalloplasty
Phalloplasty, a genitourinary surgery for transmasculine patients, reconstructs a neophallus using tissue transferred from other parts of the body to the groin.
- Trial name
- NCT05897086
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Gender Incongruence, Gender Dysphoria
Sex Hormone Overdose and Misuse in Chinese Transgender and Gender Non-conforming Population
The investigators propose to investigate the definition of hormone overdose and misuse (HODM) in Chinese transgender and gender nonconforming population (TGNCs), address the incidence of HODM in Chinese TGNC population, related…
- Trial name
- HODMChina (NCT05583058)
- Testing
- Hormone Overdose and Misuse
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Gender Dysphoria, Mastectomy
Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy
The goal of this randomized, prospective, interventional clinical trial is to evaluate the use of Brijjit® in reducing the incidence of hypertrophic scarring in individuals undergoing gender-affirming bilateral double incision…
- Conditions
- Gender Dysphoria, Mastectomy, Hypertrophic Scar
- Trial name
- FMTB Brij (NCT07147166)
- Testing
- Brijjit® BP100-6 and BP-75, Control: Standard of care and normal wound dressing
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gender Dysphoria
The Relation of GnRH Treatment to QTc Interval in Transgender Females
Background: The QT interval of the electrocardiogram (ECG), corrected for heart rate (QTc), is a measure of the duration of ventricular repolarization and is a widely used marker of ventricular arrhythmia risk.
- Trial name
- NCT03078829
- Testing
- Treatment with a GnRh agonists
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, San Francisco
Gender Identity Disorder of Adult, Voiding Disorders
Transgender Post-reassignment Urogynecologic Measures and Perceptions
The intent of this mixed methods study for transgender women after gender confirmation surgery is to characterize and subsequently create a validated screening questionnaire for postoperative urologic and pelvic floor symptoms.
- Conditions
- Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
- Trial name
- NCT03293771
- Testing
- Focus group interviews, Questionnaire packet
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Gender Dysphoria
Demographic Characteristics and Psychosocial Health of Transgender People
To study demographic characteristics of subjects referred to endocrine care for gender dysphoria and their psychosocial health
- Trial name
- DyGeDem (NCT04554849)
- Testing
- Gender dysphoria psychosocial health
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria
Effects of Gender-affirming Hormone Therapy on Transgender People
This prospective cohort study aims to assess the impact of gender-affirming hormone therapy (GAHT) on transgender individuals' physical, psychological, social, and quality of life aspects.
- Trial name
- NCT06022562
- Where
- Taiwan
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Gender Dysphoria
Effect of Nitropaste in Chest Masculinizing Surgery
Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature.
- Trial name
- NCT06428669
- Testing
- Nitro-Bid 2 % Topical Ointment
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Virginia
Transgenderism, Erectile Dysfunction
Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender Persons
This study aims to explore sexual satisfaction among transgender men and their partners following the placement of erectile prostheses after phalloplasty.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- NCT06639776
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- University Hospital, Ghent
Gender Dysphoria, Transgender
Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy
The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to: 1. Optimize techniques for processing and cryopreserving testicular tissue. 2.
- Trial name
- NCT05829928
- Testing
- Infectious Disease Testing, Gonadal Tissue Removal
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Gender Dysphoria in Adolescents and Adults
Transgender Therapeutic Support Groups
This study seeks to explore the effects for transgender people undergoing surgical interventions of participating in pre/post-surgical therapeutic support groups in order to assess the value of adding these programs to hospital…
- Trial name
- NCT04217707
- Testing
- Pre- and Post-Surgical Transgender Therapeutic Support Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Transgenderism, Erectile Dysfunction
Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients
This study seeks to explore the various methods used by transgender men for sexual intercourse following phalloplasty or metoidioplasty, focusing on their satisfaction with different erectile aids, as well as the satisfaction of…
- Conditions
- Transgenderism, Erectile Dysfunction, Gender Dysphoria, Sexual Dysfunction
- Trial name
- AID (NCT06639763)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent