Clinical trials: Gender
Coronary Artery Disease, Angina Pectoris
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- CU-PCP (NCT02158754)
- Testing
- Corus CAD (ASGES)
- Where
- 9 sites in United States
- Sponsor
- CardioDx
Osteoarthritis, Inflammatory Arthritis
Gender Solutions Natural Knee Post-Market Study
This is a prospective multicenter study of the Gender Solutions Natural Knee Flex System when used in primary total knee arthroplasty.
- Conditions
- Osteoarthritis, Inflammatory Arthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT01463566
- Testing
- Zimmer Gender(R) Solutions(TM) Natural-Knee(R) Flex System
- Sponsor
- Zimmer Biomet
Microdeletion Syndromes, Trisomy 21
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
The purpose of this study is to collect blood from families with a child who has been diagnosed with a chromosomal disorder including microdeletions in order to further develop a non-invasive prenatal screening test based on…
- Conditions
- Microdeletion Syndromes, Trisomy 21, Trisomy 18, Trisomy 13
- Trial name
- Microdel Triad (NCT02109770)
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- Natera, Inc.
Fragile X Syndrome
Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome
The study objective is to explore the efficacy, safety and tolerability of STX209 for treatment of irritability in subjects with FSX.
- Trial name
- NCT00788073
- Testing
- STX209
- Where
- 12 sites in United States
- Volunteers
- 63 people
- Sponsor
- Seaside Therapeutics, Inc.
Substance Abuse, HIV Infections
Stonewall Treatment Evaluation Project
This treatment outcome evaluation of the Stonewall Project will recruit 150 participants to complete a face-to-face assessment visit at baseline, 3-month follow-up, and 6-month follow-up to examine treatment outcome with respect…
- Trial name
- STEP (NCT01129401)
- Testing
- Stonewall Project
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
HIV Infections
Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men
This study will evaluate the effectiveness of a specialized cognitive-behavioral counseling intervention in reducing sexual risk behaviors in men who are HIV-infected and report having unprotected sex with male partners who are…
- Trial name
- NCT00218712
- Testing
- Cognitive behavioral intervention, Standard counseling
- Where
- 2 sites in United States
- Volunteers
- 488 people
- Sponsor
- University of California, San Francisco
Healthy Volunteers
Strength and Balance in Gender- and Age-Matched Controls
The purpose of this study is to learn more about balance and strength in an elderly population (60 and older). Data will be compared between controls and the age/gender- matched PD participants in study "The Effects of vitamin D…
- Trial name
- VITDC (NCT02110875)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Core Temperature, Heat Stress, Exertional
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part I
Workplaces rely on upper heat stress limits provided by the American Conference of Governmental Industrial Hygienists (ACGIH) to manage the health and safety of workers in hot environments.
- Conditions
- Core Temperature, Heat Stress, Exertional, Heat Fatigue, Exercise
- Trial name
- NCT05847712
- Testing
- Simulated work in the heat
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Turner Syndrome, Peripheral Angiopathy
AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)
Turner syndrome is a genetic condition, rare, due to the total or partial absence of one X chromosome, affecting 1/2500 newborn female. It combines almost constantly short stature and ovarian failure with infertility.
- Conditions
- Turner Syndrome, Peripheral Angiopathy, Vascular Malformation, Lymphedema
- Trial name
- AVAST (NCT02250456)
- Testing
- Echo doppler
- Where
- 6 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Strasbourg, France
Pregnancy, Long QT Syndrome
Ventricular Repolarization During the Pregnancy-to-Postpartum Transition (QuTe)
Pregnancy and the postpartum period are accompanied by marked changes in heart rate, circulating hormones, and electrolyte balance that may influence ventricular repolarization.
- Trial name
- QuTe (NCT02931695)
- Testing
- Evaluation of QT interval duration, Circulating sex hormones levels sample
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Tobacco Use Disorder
Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers
This phase I trial studies how well Flexiquit+ helps young adult smokers who identify as a sexual and/or gender minority to quit or cut down on smoking.
- Trial name
- EQQUAL (NCT04194918)
- Testing
- Computer-Assisted Smoking Cessation Intervention, Text Message, Handout
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Fred Hutchinson Cancer Center
Substance Abuse, Sexual Behavior
Seek, Test, and Retain. Linkages for Black HIV+, Substance-Using MSM
The study will seek and recruit substance-using Black Men who have Sex with Men (MSM) in New York City for Human Immunodeficiency Virus (HIV) testing and will link and retain those who are HIV infected in HIV primary care.
- Trial name
- STAR (NCT01790360)
- Testing
- Patient Navigation (PN) Intervention, Financial Incentives (FI) Intervention
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Columbia University
Position Sense, Sex Characteristics
Shoulder Proprioception: a Comparative Study on Hand Dominance and Sex
The goal of this cross-sectional study is to examine the differences in proprioception sensation depending on sex and dominant side factors in healthy volunteers.
- Conditions
- Position Sense, Sex Characteristics, Glenohumeral Joint, Upper Extremity
- Trial name
- NCT06602427
- Testing
- Shoulder proprioception measurement using isokinetic dynamometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Congenital Adrenal Hyperplasia
Adult Height Prediction in Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia (CAH) is a genetic rare disease, which alters the adrenal production of gluco and mineralo corticoïds. The treatment consists in supplementing children with hydrocortisone.
- Trial name
- OPALE Model (NCT03162159)
- Testing
- Collection of growth and bone maturation data
- Where
- France
- Volunteers
- 496 people
- Sponsor
- Hospices Civils de Lyon
Acute Myeloid Leukemia
Bone Marrow Angiogenesis in Acute Myeloid Leukemia - Evaluated by Dynamic Contrast Enhanced Magnetic Resonance (MR) Image
In malignant or neoplastic disease, angiogenesis is defined as the generation of new capillaries from preexisting blood vessels, e.g. by sprouting or by intusseption.
- Trial name
- NCT00172562
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Coronary Syndrome, Myocardial Infarction
Use of Abbott High Sensitivity Troponin I Assay In Acute Coronary Syndromes
Hypothesis: High sensitivity cTnI assays will have improved diagnostic accuracy for type 1 MI compared to contemporary cTnI assays.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Troponin
- Trial name
- UTROPIA (NCT02060760)
- Where
- United States
- Volunteers
- 1,927 people
- Sponsor
- Hennepin Healthcare Research Institute
HIV Infections, Herpes Genitalis
HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, Peru
The purpose of this study is to provide biomedical and behavioral information that is necessary for planning and starting HIV prevention trials in Lima, Peru.
- Conditions
- HIV Infections, Herpes Genitalis, HIV Seronegativity, Syphilis
- Trial name
- NCT00023582
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Polycystic Ovary Syndrome, Anovulation
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
The purpose of our study was to conduct a placebo controlled, double-blind randomized trial in chronic oligoovulatory or anovulatory , hyperandrogenic, infertility patients comparing the effects of adjuvant metformin plus…
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility
- Trial name
- NCT00413179
- Testing
- Metformin, Clomiphene citrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Gender Dysphoria
Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery
For genital gender affirming surgery, it remains unclear to what extent genital sensitivity might be expected and what the impact of this might be on sexual functioning.
- Trial name
- PROGAS (NCT04993469)
- Testing
- Semmes-Weinstein monofilament testing and questionnaires
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Gambling
Topiramate on Gambling-Related Behaviours
The quest for an effective medication therapy for problem gambling remains an important priority for the problem gambling treatment research field.
- Trial name
- NCT00370188
- Testing
- Topiramate
- Where
- Canada
- Sponsor
- Centre for Addiction and Mental Health