Clinical trials: Gastrostomy
Gastric Cancer, Surgery
Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer
The primary aim of this trial is to rigorously evaluate the comparative benefits and potential risks associated with Billroth II reconstruction with Braun anastomosis versus Billroth II reconstruction alone following distal…
- Conditions
- Gastric Cancer, Surgery, Anastomosis, Gastrostomy
- Trial name
- NCT06229197
- Testing
- Billroth II reconstruction, Braun Anastomosis
- Volunteers
- 176 people
- Sponsor
- Sichuan University
Aspiration Pneumonias, Tube Feeding
Percutaneous Endoscopic Gastrostomy Versus Percutaneous Endoscopic Gastrostomy With Jejunal Extension
The goal of this clinical trial is to learn if placing a feeding tube with a small bowel extension (called Percutaneous Endoscopic Gastrostomy With Jejunal Extension [PEG-J]) is better at preventing pneumonia than a standard…
- Conditions
- Aspiration Pneumonias, Tube Feeding, Enteral Feeds
- Trial name
- NCT06717321
- Testing
- (Arm 1): PEG, (Arm 2): PEG-J
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Jerry Dang
Dysphagia, Peristomal Wound Infection
The Influence of Oral Hygiene on Local Wound and Systemic Infection in Patients With Percutaneous Endoscopic Gastrostomy Placement
Percutaneous endoscopic gastrostomy (PEG) is commonly used for long term enteral feeding of patients with severe dysphagia. The most common complication is peristomal wound infection.
- Trial name
- PEG (NCT00859235)
- Testing
- Chlorhexidine gluconate 0.2%, Plain water
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Progressive Familial Intrahepatic Cholestasis
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders
Progressive familial intrahepatic cholestasis (PFIC) is a group of disorders that can present early in life with cholestasis and intractable pruritus.
- Trial name
- NCT04071197
- Testing
- Gastostomy-biliary tube, External biliary diversion, internal biliary diversion and nasobiliary tube
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- National Liver Institute, Egypt
Oral Mucositis, Xerostomia
Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)?
Mucositis and xerostomia are the most common complications of head and neck (H\&N) irradiation, and the combination of chemotherapy and radiation therapy is associated with a significantly higher rate of complications.
- Conditions
- Oral Mucositis, Xerostomia, Weight Loss, Head and Neck Cancer
- Trial name
- NCT00431925
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Hadassah Medical Organization
Recurrent Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Squamous Cell Carcinoma
A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
This was a multi-center, open-label, Phase Ib dose escalation /Phase II study in recurrent or metastatic head and neck squamous cell carcinoma (RM HNSCC) patients considered to be resistant, ineligible or intolerant to…
- Trial name
- NCT01602315
- Testing
- BYL719 as film-coated (FC) whole tablets, BYL719 as dispersible tablets (DT), cetuximab
- Where
- 29 sites in United States, Australia and 7 more
- Volunteers
- 179 people
- Sponsor
- Novartis Pharmaceuticals
Stroke, Ischemic
Effects of Gastrostomy and Oral Tube Feeding on Patients With Dysphagia After Stroke
The goal of this clinical trial is to compare the differences in swallowing function, quality of life and nutritional status between ischemic stroke patients with dysphagia using Intermittent Oro-esophageal Tube and Gastrostomy.
- Trial name
- NCT06818513
- Testing
- routine rehabilitation therapy, Gastrostomy, Oral tube feeding
- Volunteers
- 150 people
- Sponsor
- Muhammad
Gastrostomy Tube
Complications Associated With Primary Placement of Gastrostomy for Feeding
The purpose of the study is to compare pain, complications, and quality of life after gastrostomy tube is placed by either percutaneous endoscopic gastrostomy (PEG) or radiologically-inserted gastrostomy (RIG) method.
- Trial name
- NCT05173935
- Testing
- Percutaneous endoscopic gastrostomy, Radiologically-inserted gastrostomy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Amyotrophic Lateral Sclerosis
Dysphagia, QoL and Attitudes Towards PEG in ALS Patients
In Amyotrophic Lateral Sclerosis, dysphagia has a high incidence. With deterioration of swallowing function, percutaneous endoscopic gastrostomy (PEG) tube is recommended to ensure sufficient and safe oral intake.
- Trial name
- ALSDPEG (NCT05336760)
- Testing
- Iowa Oral Performance Instrument (IOPI), Mann Assessment of Swallowing Ability (MASA), Fiberoptic Endoscopic Evaluation of Swallowing
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Gastrostomy, Gastrostomy Complications
Safety and Efficacy of Endoscopic Assisted Push Gastrostomy Using Gastrostomy Technique
Most pediatric gastroenterologists use an endoscopic pull technique to place gastrostomy tubes. We assessed an endoscopic gastropexy technique for gastrostomy tube placement that allows immediate placement of a low profile…
- Conditions
- Gastrostomy, Gastrostomy Complications, Gastrostomy Tube Site Complication, Pain, Postoperative
- Trial name
- NCT04096456
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- CHRISTUS Health
Esophageal Squamous Cell Carcinoma, Chemoradiotherapy
To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy
This study prospectively recruited esophageal squamous-cell carcinoma patients who received nasogastric tube (NG), gastrostomy feeding and oral intake to compare the changes in nutritional status and quality of life during…
- Conditions
- Esophageal Squamous Cell Carcinoma, Chemoradiotherapy, Enteral Nutrition
- Trial name
- NCT04199832
- Testing
- Dietary guidance
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Malnutrition, Gastrostomy
Weight Loss and Gastrostomy Tube Care Outcomes in Head and Neck Cancer Patients With Gastrostomy Tube Placement
Poor nutritional status and malnutrition are prevalent for patients undergoing treatment for head and neck cancer. Inadequate dietary intake is multi factorial, with patients experiencing dysphagia and or anorexia caused by…
- Trial name
- G-Tube (NCT02775721)
- Testing
- Nursing Education related to Gastrostomy Tube Care, Speech Therapy Education and Evaluation, Nutritional Therapy Education and Evaluation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. John Health System, Oklahoma
Gastrostomy, Methods
Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques
Endoscopic placement of a percutaneous gastrostomy tube is a safe, efficient and well standardized technique. Two variants of this maneuver - the pull and the push techniques - are widespread worldwide.
- Trial name
- NCT01463540
- Testing
- A 20 Fr gastrostomy tube, placed using push/pull techniques., A 20 Fr balloon type tube, placed after gastropexy.
- Where
- 3 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Progressing Stroke
Effect of ınformatıon to caregıvers of Stroke patıents wıth Percutaneous endoscopıc Gastrostomy
Stroke is one of the serious neurological disorders that occur due to decreased blood flow to a certain part of the brain due to vascular injuries.
- Trial name
- NCT06896058
- Testing
- Written and verbal training given to caregivers
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pancreatic Fistula
Buttressed Pancreatico-Gastrostomy for Soft Pancreas With Small Diameter Pancreatic Duct in Whipple Procedure
Post-operative pancreatic fistula after Pancreaticoduodenectomy procedure, is still a major complication that might be affected by pancreatic stump reconstruction technique. More than 60 techniques were published in literature.
- Trial name
- NCT05682768
- Testing
- Duct to Mucosa Pancreatico-Gastrostomy with trans-pancreatic transverse mattress U- Shaped sutures
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- South Valley University
Feeding Difficulties, Gastrostomy
The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 3)
Using a longitudinal cohort design, we will compare the impact of a high BA-binding blenderized diet compared to a low BA-binding blenderized diet and an amino acid-based formula, on gastrointestinal and pulmonary hospitalization…
- Conditions
- Feeding Difficulties, Gastrostomy, Aspiration
- Trial name
- NCT06913621
- Testing
- amino acid formula, low bile acid binding blenderized diet, high bile acid binding blenderized diet
- Volunteers
- 138 people
- Sponsor
- Boston Children's Hospital
Gastric Cancer, Gastrostomy
Function Preserving Gastrectomy for T1/2 Gastric Cancer Patients
The real world based multi-cohorts study aims to evaluate the safety and effectiveness of function preserving gastrectomy including pylorus-preserving distal gastrectomy, proximal gastrectomy and wedge gastrectomy for T1 and T2…
- Trial name
- NCT03874871
- Testing
- Function preserving gastrectomy, Standard gastrectomy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University
Gastrostomy
Predictive Factors for Roux Stasis Syndrome
Patients who were pathologically diagnosed with gastric cancer and underwent distal gastrectomy with R-Y reconstruction between March 2014 and March 2021 were retrospectively analyzed.
- Trial name
- PFRSS (NCT04919577)
- Testing
- X-ray
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Peking University Third Hospital
Feeding Tube
Self-Propelled Versus Standard Percutaneous Endoscopic Gastrojejunostomy(PEG-J); RCT
Our main hypothesis is that self-propelled Percutaneous Endoscopic Gastrojejunostomy tube (PEG-J) that has a balloon on it's tip is associated with lower J-tube retrograde migration rate, and lower rates of short- and long-term…
- Trial name
- NCT01892267
- Testing
- PEG-J placement
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Feeding Difficulties, Gastrostomy
The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 2)
Using a four-week randomized, crossover study design, we will assess the impact of 2 weeks of a high bile acid-binding blenderized diet, compared to 2 weeks of a low bile acid-binding blenderized diet, on gastric and salivary…
- Conditions
- Feeding Difficulties, Gastrostomy, Aspiration
- Trial name
- NCT07303868
- Testing
- Low bile acid binding blenderized diet, High bile acid binding blenderized diet
- Volunteers
- 66 people
- Sponsor
- Boston Children's Hospital