Clinical trials: Gastroenteritis Acute
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Acute Appendicitis
Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis
Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operation.
- Trial name
- APPAC (NCT01022567)
- Testing
- Appendicectomy, Ertapenem
- Where
- 6 sites in Finland
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Healthy
Environmental Game After Appendicitis Surgery
This study was conducted to determine the effect of environmental play and mobilization on fear and pain levels of children aged 6-12 years who had acute appendicitis surgery.
- Trial name
- NCT05104021
- Testing
- game
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Okan University
LRTI, UTI
Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections
This is an observational prospective study of an in-vitro diagnostic (IVD) assay planned to enroll 632 subjects. The study will be conducted in two stages: Stage A is aimed at identifying individual biomarkers and constructing a…
- Conditions
- LRTI, UTI, Gastroenteritis, Systemic Infections/Bacteremia/Meningitis
- Trial name
- CURIOSITY (NCT01917461)
- Where
- 2 sites in Israel
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Appendicitis Acute
Online Field Test of an Appendicitis Decision Support Tool
After the recent publication of the CODA Trial comparing antibiotics and surgery for acute appendicitis, the investigators developed a comprehensive decision support tool.
- Trial name
- NCT05219786
- Testing
- Appendicitis Decision Support Tool, Control Infographic
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ulcerative Colitis (UC), Ulcerative Colitis (Disorder)
A Phase I Study to Evaluate the Safety/Tolerability of BDHK-2009 Tablets in Healthy Adult
A Phase 1, 2-part, randomised, double-blind, placebo-controlled, FIH study to determine the safety, tolerability, and PK of single, ascending oral doses (SAD) of BDHK-2009 (Part 1) and multiple oral doses (Part 2) of BDHK-200 in…
- Conditions
- Ulcerative Colitis (UC), Ulcerative Colitis (Disorder), Ulcerative Colitis Acute, IBD (Inflammatory Bowel Disease)
- Trial name
- NCT07632573
- Testing
- BDHK-2009 Tablets
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Benethera (Shaoxing) Biotechnology Co., Ltd.
Bronchiolitis, Gastroenteritis
Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age
With the use of molecular methods new viruses have been detected in respiratory and gastrointestinal tracts of both patients and asymptomatic subjects in recent years.
- Conditions
- Bronchiolitis, Gastroenteritis, Convulsion, Febrile
- Trial name
- NCT00987519
- Where
- 3 sites in Slovenia
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Inflammatory Bowel Diseases
Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients
This is a clinical trial of nabilone for patients with Inflammatory Bowel Disease (IBD) who are undergoing IBD-related surgery (Any abdominal surgery lasting for more than one hour).
- Trial name
- NCT03422861
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock
Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial
Background: China's healthcare system for children faces significant challenges, particularly due to the limited pediatric service capacity of primary healthcare institutions.
- Conditions
- Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock, Hand-foot-and-mouth Disease, Acute Appendicitis
- Trial name
- NCT06699433
- Testing
- Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos
- Where
- 3 sites in China
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Southern Medical University, China
Gastroenteritis
A Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Gastroenteritis
Dimenhydrinate, an over-the-counter, widely used drug in Canada, is an ethanolamine-derivative anti-histamine. It limits the stimulation of the vomiting center by the vestibular system, which is rich in histamine receptors.
- Trial name
- GAG (NCT00124787)
- Testing
- Dimenhydrinate
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Acute Appendicitis, Acute Appendicitis With Rupture
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial…
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess
- Trial name
- NCT04947748
- Testing
- Oral versus intravenous administration of antibacterial treatment
- Where
- Estonia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- North Estonia Medical Centre
Appendicitis (Diagnosis), Acute Appendicitis
Alvarado Score in the Meta Department
The project aims to determine the frequency of use of the Alvarado score among emergency department physicians at facilities in Villavicencio, Colombia.
- Trial name
- NCT07370896
- Where
- Colombia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Hospital Departamental de Villavicencio
Ulcerative Colitis, Ulcerative Colitis Flare
Transfer of Feces in Ulcerative Colitis 2
The goal of this placebo-controlled randomised multicenter trial is to evaluate the efficacy and safety of anaerobic prepared donor fecal microbiota transplantation (FMT) compared to autologous FMT in patient with ulcerative…
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Flare, Ulcerative Colitis Acute
- Trial name
- TURN2 (NCT05998213)
- Testing
- Fecal microbiota transplant
- Where
- Netherlands
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Appendicitis
The Circulating Fibrocyte - a Novel and Accurate Biomarker in Diagnosing Acute Appendicitis in Adults
Accurate diagnostic biomarkers for acute appendicitis (AA) are lacking. Circulating fibrocytes (CFs) are increased in inflammatory states. It is not known whether they are altered in appendicitis.
- Trial name
- NCT03988660
- Testing
- Circulating fibrocytes
- Where
- Ireland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Hospital of Limerick
Acute Gastroenteritis
Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis
The goal of this clinical trial is to test the effect of mothers' application of yogurt probiotic bacteria on relieving their young children's acute gastroenteritis in children had two to five years old.
- Trial name
- NCT06090708
- Testing
- yogurt with probiotic bacteria
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Diverticulitis and Irritable Bowel Syndrome
Incidence and Predictive Factor of Irritable Bowel Syndrome After Acute Diverticulitis in Korea
The pathogenesis of irritable bowel syndrome (IBS) is considered immune reaction of gastrointestinal tract. Therefore there is growing evidence that IBS could occur after gastroenteritis.
- Trial name
- NCT02003807
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Norovirus Acute Gastroenteritis
Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1403 and mRNA-1405 to Prevent Norovirus Acute Gastroenteritis in Healthy Adults 18 to 80 Years of Age
The purpose of the Part A Phase 1 of this study is to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1403 and mRNA-1405 in healthy adult participants 18 to 49 years of age and 60 to 80 years of age.
- Trial name
- NCT05992935
- Testing
- mRNA-1403, mRNA-1405
- Where
- 16 sites in United States, Australia
- Volunteers
- 1,407 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Irritable Bowel Syndrome
Chronic Gastrointestinal Sequelae of an Acute Outbreak of Bacterial Gastroenteritis in Walkerton Ontario
Acute Bacterial dysentery leads to chronic symptoms of disturbed bowel habit in a minority of individuals. This condition known as post infectious irritable bowel syndrome (PI-IBS) remains poorly understood.
- Trial name
- NCT00235326
- Where
- Canada
- Volunteers
- 4,561 people, healthy volunteers welcome
- Sponsor
- McMaster University
Diverticulitis
Diverticulitis: Antibiotics or Close Observation?
Rationale The prevalence of colonic diverticular disease is increasing in Western countries. Approximately 10 to 25% of patients with diverticular disease will eventually develop an episode of acute diverticulitis.
- Trial name
- DIABOLO (NCT01111253)
- Testing
- Amoxicillin-clavulanate
- Where
- 24 sites in Netherlands
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)