Clinical trials: Gall Stones, Common Bile Duct
Common Bile Duct Stone, Abdominal Massage
Effect of Abdominal Massage on Prevention of Recurrent Common Bile Duct Stones After Endoscopic Sphincterotomy
Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST) are the preferred techniques for treating common bile duct stones (CBDS) due to their advantages of minimal trauma, rapid recovery, low…
- Trial name
- NCT05892458
- Testing
- Abdominal massage
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Air Force Military Medical University, China
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Common Bile Duct Calculi
Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCP
The goal of this work is to assess the best time to perform LC combined with LCBD exploration and the feasibility and safety of such procedure in patients with combined GBS and CBDS after failure of ERCP extraction of CBD stones .
- Trial name
- NCT05823181
- Testing
- laparoscopy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gall Stone, Gall Stones, Common Bile Duct
Influence of Gut Microbiome in Gallstone Disease
The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone disease.
- Conditions
- Gall Stone, Gall Stones, Common Bile Duct, Pancreatitis, Acute Cholecystitis
- Trial name
- NCT05732480
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Acute Calculous Cholecystitiis (ACC)
INtraoperative Approach With Eventual Clearance of Common bilE Duct by SpyGlass Discover vs Sequential Strategy in Patients With Acute Calculus Cholecystitis and Intermediate/High Risk of Common BiLE Duct Stone
INACCESSIBLE trial is a randomized controlled study that compares two different strategies for the treatment of Acute Calculous Cholecystitiis (ACC) patients with high/intermediate risk of CBDS, according to the score by Khoury T…
- Trial name
- INACCESSIBLE (NCT06918626)
- Testing
- ELC + Spyglass cholangiography, ERCP + Early Laparoscopic cholecystectomy (ELC) in two stage procedures
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Choledocholithiasis, Gallstone Migration
Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile…
- Conditions
- Choledocholithiasis, Gallstone Migration, Cholecystitis, Gallstone Pancreatitis
- Trial name
- NCT02461147
- Testing
- Cholecystectomy with intraoperative cholangiogram
- Where
- Switzerland
- Volunteers
- 161 people
- Sponsor
- University Hospital, Geneva
Cholelithiasis
Optimal Handling of Common Bile Duct Calculus, a Prospective Study
The purpose is to study natural process of gallstones in common bile duct, stones less than or equal to 6 mm. And if the gallstones give any complications under 1 year follow up.
- Trial name
- NCT01708109
- Testing
- no measures taken to clear bile ductus, clearance of bile ductus
- Where
- 9 sites in Sweden
- Volunteers
- 35 people
- Sponsor
- Karolinska Institutet
Sphincter of Oddi Function
Endoclip Papillaplasty Recover Sphincter of Oddi Function After Endoscopic Sphincterotomy for Bile Duct Gallstones
Gallstones in the common bile duct (CBD) may be asymptomatic but may lead to complications such as acute cholangitis or acute pancreatitis. EST is widely used for the treatment of bile duct gallstones.
- Trial name
- NCT04183036
- Testing
- Endoclip papillaplasty
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Peking University Third Hospital
Choledocholithiasis, Large Common Bile Duct Stone
Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones
Bile duct stone extraction is impossible after endoscopic sphincterotomy (ES) alone in approximatively 10% of cases (mostly because of stones' size).
- Trial name
- NCT02592811
- Testing
- ERCP, Endoscopic Sphincterotomy, Large Balloon Dilatation of Oddi Sphincter
- Volunteers
- 150 people
- Sponsor
- Société Française d'Endoscopie Digestive
Cholecystolithiasis, Common Bile Duct Gall Stones
ChOlanGiography Performed Routinely Versus Selectively During Cholecystectomy: A NAtional Registry-based Randomized Controlled Trial
Common bile duct stones (CBDS) may be asymptomatic but can cause pancreatitis, obstructive jaundice, and/or cholangitis. In Sweden, intraoperative cholangiography (IOC) is usually performed during gallstone surgery in order to…
- Trial name
- COGNAC (NCT07002619)
- Testing
- Routine cholangiography, Selective cholangiograpy
- Where
- Sweden
- Volunteers
- 6,000 people
- Sponsor
- Karolinska Institutet
Common Bile Duct Calculi
Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube Drainage
This observational study aims to compare two techniques for closing the common bile duct incision (choledochotomy) after laparoscopic common bile duct exploration (LCBDE) with T-tube drainage.
- Trial name
- NCT07345663
- Testing
- Modified continuous suture, Interrupted suture
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Yantai Affiliated Hospital of Binzhou Medical University
Choledocholithiasis, Asymptomatic Condition
The Treatment Effect for Asymptomatic Common Bile Duct Stone
This study is prospective, multicenter study for identify the characteristics of asymptomatic common bile duct stones and effectiveness of treatment.
- Conditions
- Choledocholithiasis, Asymptomatic Condition, Quality of Life
- Trial name
- NCT06215040
- Testing
- Endoscopic retrograde cholangiopancratography
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Gall Stone, Common Bile Duct Calculi
Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis
- Trial name
- LERV (NCT07008170)
- Testing
- Laparoendoscopic rendezvous
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Common Bile Duct Gall Stones, Common Bile Duct GallStones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS.
- Trial name
- NCT02329977
- Testing
- standard barium meal examination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Air Force Military Medical University, China
Common Bile Duct Calculi
Symbolic Regression Model To Predict Choledocholithiasis
Choledocholithiasis refers to the presence of gallstones within the common bile duct. It is proposed to look for markers that help in the diagnosis and in differentiating between retained and migrated gallstones.
- Trial name
- (SymChole) (NCT04410848)
- Testing
- To determine the diagnostic of Choledocholithiasis with symbolic regression model
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Acute Pancreatitis, Acute Pancreatic Necrosis
coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis
Acute pancreatitis (AP) is an inflammatory disease of the pancreas, most commonly caused by gallstones, or excessive use of alcohol. It represents a management challenge and a significant healthcare burden.
- Conditions
- Acute Pancreatitis, Acute Pancreatic Necrosis, Acute Pancreatitis Due to Gallstones, Acute Pancreatic Fluid Collection
- Trial name
- MANCTRA-1 (NCT04747990)
- Testing
- Early Definitive Treatment
- Where
- 3 sites in Italy, Spain
- Volunteers
- 600 people
- Sponsor
- University of Cagliari
Common Bile Duct Stones
Common Bile Duct Stone Management: What Have we Learned?
In unfit elderly people with comorbid disease leaving the gallbladder in situ is justified after ERCP treatment. Cholangitis is more present in elderly people.
- Trial name
- CBDS (NCT02155244)
- Volunteers
- 101 people
- Sponsor
- Ospedale Regionale di Mendrisio
Pancreatitis, Cholangitis
preGallstep - A Clinical Pilot Trial
In Denmark, more than 7500 cholecystectomies are performed every year. Common bile duct gallstones (CBDS) are found in 3.4% to 18% of patients undergoing cholecystectomy.
- Conditions
- Pancreatitis, Cholangitis, Cholecystitis; Gallstone, Jaundice, Obstructive
- Trial name
- NCT04801238
- Testing
- LCBDE + LC, ERC + LC
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Lars Tue Sorensen
Common Bile Duct Calculi, Laparoscopic Abdominal Surgery
Safety and Feasibility of Early T-tube Cholangiography Performed Within 2 to 3 Days After Laparoscopic Common Bile Duct Exploration
Current clinical evidence indicates that 10-20% of patients with symptomatic cholelithiasis present with concomitant common bile duct stones (CBDS), a clinical scenario requiring tailored therapeutic approaches.
- Conditions
- Common Bile Duct Calculi, Laparoscopic Abdominal Surgery, Cholangiography
- Trial name
- LCBDE (NCT07058740)
- Testing
- early cholangiography
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Piyou Ji
Common Bile Duct Stone
Management of Borderline Common Bile Duct Stone
Evaluation of the best line of treatment of borderline CBD stones associated with gallbladder stones whether by conservative treatment or endoscopic stone extraction as regard complete clearance rate of the CBD stones followed by…
- Trial name
- CBDS (NCT02460523)
- Testing
- conservative, ERCP
- Volunteers
- 35 people
- Sponsor
- Mansoura University