Clinical trials: Gall Bladder Pain
Acute Cholecystitis, Postoperative Pain
Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis
This study aims to compare the effectiveness of irrigation of 0.5% bupivacaine versus normal saline at the gallbladder surgical bed in reducing postoperative pain following laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- NCT07851935
- Testing
- Bupivacaine 0.5%, Normal Saline 0.9%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Ziauddin University
Biliary Colic
Study on the Immediate Analgesic Effect of Yanglingquan Acupoint Treatment for Biliary Colic
Guided by traditional meridian and acupoint theory, conducting standardized, large-sample, multicenter randomized controlled trials (RCTs) to evaluate the clinical efficacy of pattern differentiation and meridian-based acupoint…
- Trial name
- NCT07194655
- Testing
- Acupuncture at the Yanglingquan point, Acupuncture at the Xiabai Point, Acupuncture at non-meridian points
- Volunteers
- 248 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Postoperative Pain, Acute Cholecystitis
USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects.
- Conditions
- Postoperative Pain, Acute Cholecystitis, Cholelithiasis, Postoperative Nausea and Vomiting
- Trial name
- NCT07552701
- Testing
- M-TAPA Group, RIFPB Group
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Hitit University
Cholelithiasis, Symptomatic Gallstone Disease
Hasson Versus Veress Access With Umbilical Versus Epigastric Gallbladder Extraction in Laparoscopic Cholecystectomy
This single-centre randomised pilot study compared two strategies for primary abdominal access and gallbladder extraction in elective laparoscopic cholecystectomy: open (Hasson) umbilical access with extraction of the gallbladder…
- Trial name
- NCT07887139
- Testing
- Hasson open access and umbilical gallbladder extraction, Veress needle access and epigastric gallbladder extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sedat Tan
Cancer Pain, Visceral Pain
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL).
- Conditions
- Cancer Pain, Visceral Pain, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract
- Trial name
- NCT04907643
- Testing
- PICO G2 4k
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain
Effectiveness of Bupivacaine After Laparoscopic Cholecystectomy
Evaluate the efficacy on postoperative pain of the positioning of a 0,5% bupivacaine soaked-tabotamp in gallbladder bed after videolaparoscopic cholecystectomy.
- Trial name
- NCT00599144
- Testing
- videolaparocholecystectomy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Santa Maria alla Gruccia Hospital
PONV, Postoperative Pain
Pain and Nausea After Gallbladder Surgery
The study is primarily an exploratory study of quality registry data for a swedish national cohort of patients who have undergone gallbladder surgery or ERCP, with the aim of investigating the occurrence of pain and PONV…
- Conditions
- PONV, Postoperative Pain, Postoperative Complications, Gall Bladder Disease
- Trial name
- NCT06083558
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Umeå University
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Biliary Tract Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine and gemcitabine, use different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer, Pain
- Trial name
- NCT00073905
- Testing
- capecitabine plus gemcitabine
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Swiss Cancer Institute
Gallbladder Inflammation
Vitamin C Efficacy in Reducing Post Operative Pain
Opioids are the corner stone in the treatment of post operative pain. Because of the several side effects of opiods, non-steroidal anti-inflammatory drugs are usually added postoperatively to decrease the total requirements of…
- Trial name
- NCT01322061
- Testing
- Ascorbic Acid
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- American University of Beirut Medical Center
Cholelithiasis (Without Cholecystitis), Cholecystitis, Acute
Comparison of Gallbladder Extraction Via Subxiphoid vs Infraumbilical Port in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the standard surgical treatment for symptomatic gallstone disease due to its advantages in reducing postoperative pain and recovery times.
- Trial name
- NCT07672145
- Testing
- Subxiphoid Gallbladder Retrieval, Infraumbilical Gallbladder Extraction
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- King Edward Medical University
Benign Gallbladder Disease, Laparoscopic Cholecystectomy
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Laparoscopic Cholecystectomy
After laparoscopic cholecystectomy, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the…
- Conditions
- Benign Gallbladder Disease, Laparoscopic Cholecystectomy, Postoperative Pain, Quality of Recovery
- Trial name
- REVISED-PVB II (NCT07566819)
- Testing
- Revised-Paravertebral Nerve Block
- Volunteers
- 250 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Surgery, Pain, Post Operative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll.
- Trial name
- CARES for Kids (NCT06671002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 9 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Cholecystectomy, Laparoscopic, Pain Management
The Ideal Local Anesthetic for Intraperitoneal Gallbladder Bed Infiltration Following Laparoscopic Cholecystectomy
To control pain after surgery for removal of gallbladder, local anesthetic agent can be sprayed on the liver bed from where the gallbladder is removed.
- Trial name
- NCT06605235
- Testing
- Local Anesthesia
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Cholecystitis, Pain
The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main…
- Conditions
- Cholecystitis, Pain, Nausea
- Trial name
- NCT06927817
- Testing
- hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cholecystitis
Ondansetron Effect on Pain Relief After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) is an easy procedure characterized by its minimal invasiveness, less post-operative pain and early recovery when compared to the open conventional cholecystectomy.
- Trial name
- NCT04468685
- Testing
- Ondansetron, Normal saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Pain, Acute
Gall Bladder Bed Infiltration Analgesia
Early postoperative pain is a common complaint after elective laparoscopic cholecystectomy. Persistent acute postoperative pain is the dominating complaint and the primary reason for a prolonged stay after this procedure.
- Trial name
- NCT03693820
- Testing
- the infiltration group, the control group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alaa Mazy Mazy
Cholecystitis, Cholecystitis, Acute
M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Cholesistectomy
Ultrasound (US)-guided Modified Perichondral Approach Thoracoabdominal Nerve (M-TAPA) block is a novel block that provides effective analgesia in the anterior and lateral abdominal walls after laparoscopic surgery, and local…
- Trial name
- NCT05502159
- Testing
- M-TAPA, EOB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Cholecystitis
Prophylactic TAP Block in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the gold standard for cholelithiasis, yet postoperative pain remains a clinical challenge. Ultrasound-guided transversus abdominis plane (TAP) block has been proposed as an effective analgesic…
- Trial name
- NCT07871617
- Testing
- Analgesic, Analgesic transversus abdominal plane blockade (Bupivacaine)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Cholecystolithiasis
Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy
The purpose of this study is to determine the effect of warmed, humidified carbon dioxide Insufflation vs standard carbon dioxide in laparoscopic cholecystectomy.
- Trial name
- NCT01667848
- Testing
- Optitherm® device activated, Optitherm® device inactivated
- Where
- Austria
- Volunteers
- 148 people
- Sponsor
- Kepler University Hospital