Clinical trials: Gait Impairment
Idiopathic Normal Pressure Hydrocephalus (INPH)
Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)
The goal of this observational study is to describe changes in cognitive profile and frailty from pre shunt to one year after the shunt surgery and to identify clinical predictors of an improvement in terms of cognition and…
- Trial name
- NCT07642726
- Testing
- Ventriculoperitoneal shunt
- Where
- Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Myelopathy Cervical
Evaluation of Gait Impairment and Correlation in Patients With DCM
This study aims to evaluate gait impairment in patients with Degenerative Cervical Myelopathy (DCM) before and after surgery using an inertial measurement unit (IMU) sensor.
- Trial name
- DCM-HFIMU (NCT06719375)
- Testing
- Gait Analysis Using IMU Sensor
- Volunteers
- 30 people
- Sponsor
- Pusan National University Yangsan Hospital
Spinal Cord Injury (SCI), Gait
Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)
The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in…
- Conditions
- Spinal Cord Injury (SCI), Gait, Reduced Physical Activity, Lower Limb Functions
- Trial name
- NCT07689227
- Testing
- CLV
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Lumbar Spinal Stenosis
Assessment of Gait Parameters and Their Impact on Postoperative Recovery in Patients With Lumbar Spinal Stenosis
The objective is to observe the evolution of walking parameters during the surgery process and find which of all calculated walking parameters represent the best indicators of functional disabilities and postoperative recovery…
- Trial name
- NCT04250753
- Testing
- Walking task
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Université du Québec à Trois-Rivières
Mild Cognitive Impairment
Maze Activities' Impact on Balance and Gait in Cognitively Impaired Children
This study aims to evaluate the effect of the Minds in Motion Maze program on balance and gait in children with cognitive impairment. It focuses on how movement-based, sensory-integrated activities can improve motor performance.
- Trial name
- NCT07729865
- Testing
- mind in motion maze activity, baseline activities
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Palsy
Exoskeleton-assisted Physiotherapy for Children With Mobility Impairments
Non-ambulatory children with cerebral palsy (CP) and similar childhood-onset neuromotor conditions face many challenges to fulsome participation in everyday life.
- Trial name
- NCT05463211
- Testing
- Trexo Plus Pediatric Exoskeleton
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Craniocerebral Trauma, Traumatic Brain Injury
Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.
The aim of this study is to determine effect of proprioceptive stimulation with passive gait training on the cortical activity in patients with severe brain injury, demonstrated as changes in EEG (electroencephalogram)and ERP…
- Conditions
- Craniocerebral Trauma, Traumatic Brain Injury, Subarachnoid Hemorrhage, Anoxic Brain Injury
- Trial name
- NCT00526500
- Testing
- Tilt Table With Integrated Stepping System
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fallers, Mild Cognitive Impairment
Temporal Relations and Exercise Interventions of Various Gait and Cognitive Domains in Older Adults
The effectiveness of conventional exercise, tai chi chuan and health education/usual physical activity over a 6-month intervention period in improving primary outcomes and secondary outcomes in older mild cognitive impairment…
- Trial name
- NCT03839563
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater
Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
The goal of this clinical trial is to investigate whether sensory stimulations from a neuroprosthesis device (Walkasins®) can increase physical activity and improve gait quality in persons with peripheral neuropathy (PN).
- Conditions
- Peripheral Neuropathy With Type 2 Diabetes, Peripheral Neuropathy Grade 2 or Greater, Balance, Balance Impairment, Gait Disorders, Fatigue
- Trial name
- NCT07554443
- Testing
- External, lower limb sensory prosthesis
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- RxFunction Inc.
Low Vision
Obstacle Negotiation in Older People With and Without Vision Impairment
Falls are common among people with vision impairment and can lead to devastating health consequences. Understanding the functions of vision and how the visual characteristics of obstacles in the walking path impact the gait of…
- Trial name
- NCT05888441
- Testing
- Obstacle characteristics
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Osteoarthritis, Gait Disorders, Neurologic
Effect of Flamingo Exercises on Balance
The aim of this study is to determine the effect of flamingo exercise on balance in patients with balance impairment due to senil osteoarthritis
- Trial name
- NCT03361449
- Testing
- Flamingo exercise, training with kinesthetic ability trainer
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Mild Cognitive Impairment
Arch Support Effects on Balance and Gait in Older Adults With Mild Cognitive Impairment
This study aims to explore the effects of arch support insoles on balance and gait performance in older adults with mild cognitive impairment (MCI). We will recruit 40 female older adults with MCI.
- Trial name
- NCT05470062
- Testing
- arch support insoles (FootDisc)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Stroke, Gait, Unsteady
A Novel Ballet-inspired Low-impact At-home Workout Programme for Adults with Stroke
To explore the feasibility of a novel ballet-inspired low-impact at-home workout programme for community-dwelling stroke survivors in Hong Kong.
- Conditions
- Stroke, Gait, Unsteady, Balance; Distorted, Memory Impairment
- Trial name
- NCT04460794
- Testing
- Ballet-inspired workouts, Usual care
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Parkinson's Disease
A Randomized Trial to Evaluate Ampyra for Gait Impairment in Parkinson's Disease
The purpose of this study is to evaluate the effect of AMPYRA on a number of symptoms in Parkinson's disease. AMPYRA is a medication approved by FDA for gait dysfunction in multiple sclerosis.
- Trial name
- NCT01491022
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Stroke
Home-Based Functional Electrical Stimulation for Lower Limb Rehabilitation in Stroke Patients.
This assessor-blinded, randomized, parallel-group feasibility trial will evaluate the feasibility and preliminary effectiveness of a home-based Functional Electrical Stimulation (FES) system for lower-limb rehabilitation in…
- Trial name
- FES (NCT07785700)
- Testing
- Functional Electrical Stimulation (FES), Standard Rehabilitation
- Where
- 3 sites in India
- Volunteers
- 70 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Stroke
Effect of Simultaneous Application of HD-tDCS and Robot-assisted Gait Training on Gait Function in Stroke Patients
The purpose of this study was to investigate the effects of simultaneous application of transcranial direct current stimulation (tDCS) with robotic gait training in stroke patients with gait impairment.
- Trial name
- NCT04985864
- Testing
- Brain stimulation, Treadmill gait training
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yun-Hee Kim