Clinical trials: Gait Impairment, open to volunteers
Aging
Gait Adaptation Study
This pilot study proposes a clinical trial to target treatment of sensorimotor and cognitive deficits in persons with Multiple Sclerosis (pwMS).
- Trial name
- NCT07660601
- Testing
- Gait Adaptation Training, Basic Physical Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Mild Cognitive Impairment (MCI), Dementia
An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)
This study tests an innovative system and service for collecting objective, consistent, and in-community gait parameters suitable for use as AD/ADRD biomarkers.
- Trial name
- NCT07127133
- Testing
- Insole and ankle device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Dementia, Dementia, Mixed
Uppsala-Dalarna Dementia and Gait Project
UDDGait™ is a multidisciplinary research project with the overreaching goal of providing an aid for early identification of cognitive impairment and risk of dementia development, thereby providing a basis for adequate symptom…
- Conditions
- Dementia, Dementia, Mixed, Dementia Senile, Dementia of Alzheimer Type
- Trial name
- UDDGait™ (NCT05893524)
- Testing
- Timed Up-and-Go (TUG single-task), Timed Up-and-Go dual-task (TUGdt), Clinical functional assessment
- Where
- 2 sites in Sweden
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Gait Apraxia, Mild Cognitive Impairment
Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times.
- Conditions
- Gait Apraxia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Cerebral Atrophy
- Trial name
- NCT03020381
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Manuel Montero Odasso
Cerebral Small Vessel Disease
Neural Correlates (EEG and fMRI) of Gait in Small Vessel Disease
What is the purpose of this study? This observational study is being done to understand how cerebral small vessel disease (SVD) affects walking and balance.
- Trial name
- doesn't exist (NCT07372937)
- Testing
- No Intervention: Observational
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe side effect of several anti-cancer agents. Typical symptoms include tingling and hypoesthesia in the fingertips and/or toes, which substantially impair patients'…
- Trial name
- Assess CIPN (NCT07315334)
- Testing
- Questionnaire and Physical Exam
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Normal Pressure Hydrocephalus
White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)
Idiopathic Normal Pressure Hydrocephalus (iNPH) is a progressive condition of the elderly that results in severe disability. iNPH can dramatically respond to Cerebral spinal fluid(CSF)-shunting where excess ventricular fluid is…
- Trial name
- OWN-NPH (NCT07103681)
- Testing
- Ventriculoperitoneal Shunt (VP), Brain and Skin Biopsy, MRI Brain
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Parkinson Disease
Pathways Mediating Impaired Postural Control in Parkinson's Disease
The purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to spinal cord) pathways that…
- Trial name
- NCT06464029
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Multiple Sclerosis, Parkinson Disease
Gait and Balance Impairment in Rare and Very Rare Neurological Diseases
Rare and very rare neurological diseases primarily or exclusively affect the nervous system with a prevalence of < 5 out of 10'000 and 100'000 people, respectively.
- Conditions
- Multiple Sclerosis, Parkinson Disease, Peripheral Neuropathy, Rare Diseases
- Trial name
- GALVANISE (NCT06343558)
- Testing
- Questionnaires, clinical scales and instrumental tests
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Gait, Physical Activity, and Sleep in Parkinson's Disease
This study aims to investigate the relationship between balance and gait impairments, physical activity levels, and sleep status in individuals with Parkinson's disease (PD).
- Trial name
- NCT07424924
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Parkinson's Disease (PD)
Perception of Affordances and Obstacle Crossing in People With Parkinson's Disease and Healthy Adults
This study aims to explore how young adults, older adults and people with Parkinson's disease (PwP), perceive their abilty to cross obstacles while walking, and how this perception is related to their actual performance of…
- Trial name
- NCT06932679
- Testing
- Assessment of Gait and Visual Exploration
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Vestibular Hypofunction, Ataxia - Other
Vibrotactile Balance Belt Effect on Improving Gait
This study will examine the effect of using a vibrotactile feedback implemented into a belt, at improving gait in those with gait disorders.
- Conditions
- Vestibular Hypofunction, Ataxia - Other, Gait Impairment
- Trial name
- BalanceBelt (NCT07253532)
- Testing
- BalanceBelt
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mild Cognitive Impairment (MCI)
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
- Trial name
- gait dementia (NCT07448909)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Low Vision
Obstacle Negotiation in Older People With and Without Vision Impairment
Falls are common among people with vision impairment and can lead to devastating health consequences. Understanding the functions of vision and how the visual characteristics of obstacles in the walking path impact the gait of…
- Trial name
- NCT05888441
- Testing
- Obstacle characteristics
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University