Clinical trials: GATA2 Gene Mutation

Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Gene Mutations

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies

• Completed
• Age: All ages
• Phase 2
• Injection or infusion
• Surgery or procedure
• Results posted

This phase II trial studies reduced-intensity conditioning before donor stem cell transplant in treating patients with high-risk hematologic malignancies.

Conditions

Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Gene Mutations, Acute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM, Acute Myeloid Leukemia With t(6;9) (p23;q34.1); DEK-NUP214

Trial name

NCT01760655

Testing

Fludarabine phosphate, Busulfan, Total-Body Irradiation

Where

United States

Volunteers

62 people

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University