Clinical trials: GAD
Anxiety Disorder (Panic Disorder or GAD), Anxiety Symptoms
Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.
Anxiety is one of the most frequent disorders during the perinatal stage which is associated with adverse health effects for women and their babies. In spite of this, preventive interventions during this stage are scarce.
- Trial name
- NCT06609291
- Testing
- Telematic Prenatal Psychological Intervention for Preventing Anxious Symptomatology
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Generalized Anxiety Disorder
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, phase 3, randomized, double-blind, parallel-group, 2-arm, placebo controlled, multicenter trial designed to compare the efficacy, safety and tolerability of a fixed dose of SEP-363856 (75 millligrams per day…
- Trial name
- NCT07767903
- Testing
- SEP-363856
- Where
- 11 sites in United States
- Volunteers
- 384 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Specific Phobia, Separation Anxiety
Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical Setting
An open trial will be conducted at the Child and Mental Health Service (CAMHS) unit in the rural county Jämtland in Sweden to test the feasibility and efficacy of Internet-delivered Cognitive Behavior Therapy (ICBT) for children…
- Conditions
- Specific Phobia, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT02306356
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Anxiety Disorders
Treatment for Anxiety in Children
The purpose of this study is to see if it is effective to treat children with anxiety disorders with fluvoxamine. Fluvoxamine has been successfully used to treat obsessive-compulsive disorder (OCD) in adults and children.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT00000389
- Testing
- Fluvoxamine
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder
Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD
Meta Cognitive Therapy (MCT) has been introduced as a new specific treatment for generalised anxiety disorder. So far, no studies have examined CBT and MCT in comparison with each other in a randomised controlled trial.
- Trial name
- NCT00426426
- Testing
- Cognitive-Behavioural Therapy, Meta-Cognitive Therapy, Waiting list
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Generalized Anxiety Disorder
6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)
This is an open-label, multi-site, 6-month study of an investigational compound in elderly outpatients, age 65 years old or above, to assess the long-term safety and tolerability of the compound in the treatment of elderly…
- Trial name
- NCT00738738
- Testing
- PD-0332334
- Where
- 2 sites in United States
- Sponsor
- Pfizer
Generalized Anxiety Disorder, Oxygenation Sensitive CMR
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
This study aims to view variations in MRI measurements of the heart and the brain in people with anxiety versus healthy volunteers.
- Trial name
- B-GLAD (NCT05574140)
- Testing
- Cardiac MRI
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anxiety Disorders
Study to Assess the Efficacy and Safety of Levetiracetam for the Treatment of Social Anxiety Disorder (Generalized Type)
Preclinical and clinical findings indicate that LEV has some anxiolytic potential. There is reason to believe that compounds with anxiolytic activity may have broad clinical utility across the anxiety spectrum.
- Trial name
- NCT00612859
- Testing
- levetiracetam
- Volunteers
- 217 people
- Sponsor
- UCB Pharma
Anxiety Disorders
Fixed Dose Study of PD 0332334 and Paroxetine for the Treatment of Generalized Anxiety Disorder
This study is a randomized, double-blind, parallel-group, multi-site, Phase 3, placebo controlled fixed-dose study of PD 0332334 and paroxetine in 528 outpatients with generalized anxiety disorder.
- Trial name
- NCT00836069
- Testing
- No drug name provided by Sponsor; drug referenced as PD 0332334, Paroxetine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Cedars-Sinai Medical Center
Major Depressive Disorder, Dysthymic Disorder
Testing a Precision Psychotherapy System for Low-income Patients
The purpose of this study is to evaluate the feasibility of an evidence-based system to recommend core interventions, before the beginning of treatment, to psychotherapists treating low-income patients with depressive or anxiety…
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Specific Phobia, Social Anxiety Disorder
- Trial name
- ML_LMIC (NCT05118594)
- Testing
- Pre-treatment psychotherapy recommendations
- Volunteers
- 111 people
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Generalized Anxiety Disorder
A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder
The purpose of this study is to evaluate the safety and efficacy of an investigational anti-anxiety medication relative to placebo in patients with generalized anxiety disorder (GAD)
- Trial name
- NCT00236054
- Testing
- Gabitril
- Where
- 19 sites in United States
- Volunteers
- 440 people
- Sponsor
- Cephalon
Autoimmune Encephalitis
Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism
Prospective cohort study evaluating FDG PET in 56 patients with confirmed autoimmune encephalitis - based on 2016 Graus criteria, and 2021 paraneoplastic neurological syndromes criteria - at the acute phase, before…
- Trial name
- ENCEPHATAIP (NCT06079294)
- Testing
- FDG PET
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety
Youth Mayo Clinic Anxiety Coach Pilot Study
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205177
- Testing
- Mayo Clinic Anxiety Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stephen Whiteside
Generalized Anxiety Disorder, Major Depressive Disorder
Improving Access to the Treatment of Anxiety and Depression Among Young Adults
Anxiety and depression represent the most common mental health problems. Unfortunately, only a minority of people in need will seek or access traditional mental health services.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03156556
- Testing
- Mood Mechanic Course
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Universite de Moncton
General Anxiety Disorder
Evaluate the Beneficial Effects of an Oral Nutritional Supplement Based on Leonurus Cardiaca for the Improvement of Mood and Anxiety
This study aims to evaluate the efficacy and safety of Leonurus cardiaca extract in reducing anxiety symptoms in adults with Generalized Anxiety Disorder (GAD).
- Trial name
- LEONORUS (NCT06954038)
- Testing
- Leonurus cardiaca extract 250 mg, Leonurus cardiaca extract 500 mg
- Volunteers
- 60 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Generalized Anxiety Disorder
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety Disorder
The purpose of this study is to demonstrate that quetiapine SR (SEROQUEL®) is efficacious and safe in the acute treatment of patients with Generalized Anxiety Disorder.
- Trial name
- GOLD (NCT00329446)
- Testing
- Quetiapine Fumarate, Escitalopram oxylate
- Where
- 63 sites in United States
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
Generalized Anxiety Disorder
Chamomile Therapy for Generalized Anxiety
This study will determine the effectiveness of chamomile extract for treating generalized anxiety disorder. Study hypotheses: 1)Chamomile extract will have a superior anti-anxiety effect compared to placebo.
- Trial name
- NCT00645983
- Testing
- Chamomile Extract
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Generalized Anxiety Disorder
Cognitive-Behavioral Treatment and Interpretation Modification Training for Adults With Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a condition characterized by chronic and excessive worry and anxiety. Our group has developed a cognitive-behavioural treatment (CBT) for GAD that has been tested in four previous clinical…
- Trial name
- CBT+IMT-GAD (NCT01681329)
- Testing
- Cognitive-behavioral therapy, Interpretation training
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Concordia University, Montreal
Questionnaire Designs, COVID-19 Pandemic
Psychological Effects of the COVID-19 Pandemic on the Hungarian Adult Population
The aim of the study is to explore the psychological effects of the COVID-19 pandemic among Hungarian adults with the use of an anonymous online questionnaire that consists of 65 items.
- Conditions
- Questionnaire Designs, COVID-19 Pandemic, Psychological Stress, Coping Skills
- Trial name
- NCT04426266
- Where
- Hungary
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Szeged University
Generalized Anxiety Disorder
Treating Young Adult Generalized Anxiety Disorder With Text-Message Delivered Cognitive Behavioral Therapy
The purpose of the proposed study is to test the feasibility and efficacy of a "anxiety-focused" text-delivered counseling program to reduce anxiety symptoms among young adults (18-25) with elevated anxiety symptoms.
- Trial name
- NCT06774573
- Testing
- CBT-txt-A
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville