Clinical trials: GAD
Generalized Anxiety Disorder
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) as an adjunctive treatment for generalized anxiety disorder (GAD).
- Trial name
- NCT07392645
- Testing
- Electroacupuncture (EA), Medication
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Lishu Gao
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Fear, GAD
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments.
- Conditions
- Fear, GAD, Emotional Memory, PTSD
- Trial name
- NCT05120635
- Testing
- Deep Brain Stimulation, Virtual and augmented reality tasks
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Pharmacokinetics
A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics
Kava is a dietary supplement on the US market and is experiencing a resurgence of its use. Its pharmacokinetic information, however, is lacking which is important for its future effective usage as a dietary supplement or…
- Trial name
- KavaPK (NCT03843502)
- Testing
- Kava Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Generalized Anxiety Disorder
Open Trial of an ACT Skills Group and Mobile App for Worry
This study is an open trial of acceptance and commitment therapy (ACT) groups combined with a mobile app for the treatment of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT03709433
- Testing
- ACT groups and mobile app
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Utah State University
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Generalized Anxiety Disorder
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study
The purpose of this research is to look at the effects of computerized cognitive training on anxiety, sleep, mental abilities (cognition), and other aspects of daytime functioning, such as arousal.
- Trial name
- COGMA (NCT04421690)
- Testing
- Cognitive Training, Trivia Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Anxiety Disorder (Panic Disorder or GAD), Anxiety Symptoms
Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.
Anxiety is one of the most frequent disorders during the perinatal stage which is associated with adverse health effects for women and their babies. In spite of this, preventive interventions during this stage are scarce.
- Trial name
- NCT06609291
- Testing
- Telematic Prenatal Psychological Intervention for Preventing Anxious Symptomatology
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Generalized Anxiety Disorder
Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD
Meta Cognitive Therapy (MCT) has been introduced as a new specific treatment for generalised anxiety disorder. So far, no studies have examined CBT and MCT in comparison with each other in a randomised controlled trial.
- Trial name
- NCT00426426
- Testing
- Cognitive-Behavioural Therapy, Meta-Cognitive Therapy, Waiting list
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Generalized Anxiety Disorder, Oxygenation Sensitive CMR
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
This study aims to view variations in MRI measurements of the heart and the brain in people with anxiety versus healthy volunteers.
- Trial name
- B-GLAD (NCT05574140)
- Testing
- Cardiac MRI
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Questionnaire Designs, COVID-19 Pandemic
Psychological Effects of the COVID-19 Pandemic on the Hungarian Adult Population
The aim of the study is to explore the psychological effects of the COVID-19 pandemic among Hungarian adults with the use of an anonymous online questionnaire that consists of 65 items.
- Conditions
- Questionnaire Designs, COVID-19 Pandemic, Psychological Stress, Coping Skills
- Trial name
- NCT04426266
- Where
- Hungary
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Szeged University
Generalized Anxiety Disorder
Treating Young Adult Generalized Anxiety Disorder With Text-Message Delivered Cognitive Behavioral Therapy
The purpose of the proposed study is to test the feasibility and efficacy of a "anxiety-focused" text-delivered counseling program to reduce anxiety symptoms among young adults (18-25) with elevated anxiety symptoms.
- Trial name
- NCT06774573
- Testing
- CBT-txt-A
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
Social Anxiety, Major Depression Mild
Transdiagnostic REBT Prevention Program for Adolescents
Anxiety and depressive disorders are common in adolescents, however they are often unrecognized. Rational emotive behavioral therapy (REBT), a form of cognitive behavioral therapy (CBT) is efficient for children and adolescents.
- Conditions
- Social Anxiety, Major Depression Mild, Panic Disorder, Specific Phobia
- Trial name
- NCT02756507
- Testing
- video-based transdiagnostic REBT, Wait list
- Where
- Romania
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Pharmacokinetics
Biomarker Changes and Anxiolytic Effects-Phase 2
This study will examine the utility of plasma and urinary based biomarkers for the anxiolytic properties of kava. The investigators will conduct a one week, double blind, randomized placebo controlled trial of kava, dosed at…
- Trial name
- KavaPK (NCT04565145)
- Testing
- Kava Dietary Supplement
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aerobic Exercise, Stretching
Lifestyle Interventions for Generalized Anxiety Disorder
This two-site (Southern Methodist University (SMU) and Boston University (BU)) study aims to examine the effectiveness of exercise interventions for the treatment of generalized anxiety disorder (GAD).
- Trial name
- NCT01644812
- Testing
- Aerobic exercise, Stretching
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University