Clinical trials: Functional Limitation
Diabetes Mellitus
Preventing Renal Functional Abnormalities With Calorie Restriction in Subjects With Abdominal Obesity and Type 2 Diabetes at Increased Renal and Cardiovascular Risk
The study investigates whether a caloric restricted dietary regime can prevent onset and/or progression of chronic kidney disease in type 2 diabetic patients with abdominal obesity, through the amelioration of concomitant…
- Trial name
- CRESO (NCT01213212)
- Testing
- Caloric restriction, No intervention
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Osteo Arthritis Knee, Worries; Pain or Disability
The Role of Rumination and Worry in Pain and Functional Limitation in Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disease in which pain severity often does not fully correspond with radiographic disease severity.
- Conditions
- Osteo Arthritis Knee, Worries; Pain or Disability, Rumination
- Trial name
- NCT07609056
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Sarcopenia, Occlusion
Effectiveness of Focal Vibration and Blood Flow Restriction Within a Multicomponent Exercise Programme.
Sarcopenia can occur or increase due to sedentary lifestyles, physical inactivity or chronic endocrine and inflammatory disorders, this pathology is much more frequent in older people due to the added risk factors and the fact…
- Conditions
- Sarcopenia, Occlusion, Vibration; Exposure, Old Age; Atrophy
- Trial name
- NCT04940702
- Testing
- Focal Vibration, Blood Flow Restriction, Traditional Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Joint Loose Bodies
Different Methods of Physical Therapy for Stroke
It is estimated that worldwide, about 15 million people are affected by vascular accident (CVA) per year, and in Brazil, the stroke is a major cause of death and disability, generating too much economic and social impact by…
- Trial name
- NCT02932631
- Testing
- THERAPY CONTROL AND MOVEMENT OF INDUCTION
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Stroke
Kinesiotaping and Constraint Induced Movement Therapy in Subacute Stroke
In stroke patients, the most common neurological deficits were motor impairment, loss of somatosensation, abnormal muscle tone, and impaired fractionated movement at affected limbs.
- Trial name
- NCT03682666
- Testing
- Kinesiotaping, modified Constraint Induced Movement Training
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Dexterity, Tendon Injuries
Does Restriction of the Dominant Hand Due to Injury Improve Non-Dominant Hand Function?
Hand injuries result in the restriction of use of the injured hand within a splint or a plaster during the first 6 weeks which is critical for tissue healing.
- Conditions
- Dexterity, Tendon Injuries, Fractures, Nerve Injury
- Trial name
- NCT06783205
- Testing
- Restriction of the Dominant Hand Due to Splint Use
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Knee Osteoarthritis
Effects of Low-Load Blood Flow Restriction Resistance Training With and Without Hip Abductor Strengthening in Patients With Knee Osteoarthritis.(BFR)
This study aims to compare the effects of low-load Blood Flow Restriction (BFR) resistance training with and without hip abductor strengthening in patients with knee osteoarthritis.
- Trial name
- yes (NCT07892144)
- Testing
- Hip Abductor Strength Training followed by Low-Load BFR Resistance Training, Low-Load Blood Flow Restriction (BFR) Resistance Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- University of Management and Technology Lahore
Pediatric Burns, Burn Injury
Plyometrics for Strength and Function After Pediatric Burns
Pediatric burn survivors may experience persistent deficits in lower-limb strength, explosive power, and functional performance after hospital discharge.
- Conditions
- Pediatric Burns, Burn Injury, Post-Burn Rehabilitation, Rehabilitation
- Trial name
- NCT07590557
- Testing
- Plyometric Training, Standard Exercise Program
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Qassim University
Cerebral Palsy, Hand Functions
The Hand Functions In Cerebral Palsy
The hand motor functions are very important in the daily life activities, educational, and social participation of children. Losing The hand motor functions limit these activities and participation.
- Trial name
- NCT05988944
- Testing
- TT+CIMT+VR, TT+CIMT, TT
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uludag University
Anterior Cruciate Ligament Injuries
Blood Flow Restriction Training in ACL Surgery
This will be a randomized pilot study to determine the effectiveness of Personalized Blood Flow Restriction (PBFR) technique in conjunction with prescribed physical therapy (PT) in a cohort of anterior cruciate ligament (ACL)…
- Trial name
- NCT05245864
- Testing
- blood flow restriction, physical therapy standard of care
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Arkansas
Hemiplegic Cerebral Palsy
Bimanual Task Training and Constraint-Induced Movement Therapy in Hemiplegic Cerebral Palsy Children
Various studies have been done comparing the individual effects of the two interventions of Constraint-Induced Movement Therapy and Bimanual Task Training in Hemiplegic Cerebral Palsy Children, but this study will compare the…
- Trial name
- NCT05380011
- Testing
- Constraint Induced Movement Therapy and Bimanual Task Training, Bimanual Task Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Low Back Pain
Effects Of 8-Week Core Stabilization Exercise With Vitamin D On Pain and Functional Limitation in Adults
Chronic non-specific low back pain (CNSLBP) is a prevalent condition contributing to pain, functional limitations, and reduced quality of life.
- Trial name
- NCT06913413
- Testing
- core stabilization exercise, stabilization exercise
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Superior University
Overweight, Obesity
The Effects of Including Almonds in a Weight Loss Trial
The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and…
- Trial name
- NCT02360787
- Testing
- Energy restriction, Almonds (15% kcal/day)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dynapenia
Blood Flow Restriction Parameters and Lower Limb Function in Older Adults With Dynapenia
The objective of the first year is to collect limb occlusion pressure (LOP) measurements in older adults with varying levels of muscle health, which will serve as foundational data for subsequent investigations on blood flow…
- Trial name
- NCT07534150
- Testing
- Blood Flow Restriction, Conventional Resistance Training
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired
Respiratory Function and Walking Capacity in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic progressive neurological disease. Respiratory dysfunction due to weakness in the respiratory musculature has been described in MS.
- Conditions
- Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired, Difficulty Walking
- Trial name
- NCT01774201
- Testing
- Breathing exercises
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Dialysis Patients
Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients
The main objective is to evaluate in hemodialysis patients the effects of two intradialytic rehabilitation programs based on physical exercise, with or without the application of blood flow restriction, on myocardial stunning and…
- Trial name
- ERO-CARD (NCT07269379)
- Testing
- Chronic phase - HDEX/HDBFRE, Acute phase - HDEX/HDBFRE
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
Asthma
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT01225913
- Testing
- fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gelb, Arthur F., M.D.
Knee Osteoarthristis
BFR Training and Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic, progressive degenerative joint disease characterized by cartilage and bone degeneration, synovial inflammation, and structural changes.
- Trial name
- NCT07590323
- Testing
- Standard Treatment, Pain neuroscience education, Blood flow restriction training
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Hail
Advanced Glycation Endproducts, AGEs
Restriction of Dietary AGEs to Prevent Diabetes in Overweight Individuals
Current efforts to arrest the epidemic of type 2 diabetes mellitus (T2DM) have had limited success. Thus there is an urgent need for effective approaches to prevent the development of T2DM.
- Conditions
- Advanced Glycation Endproducts, AGEs, Diet, Insulin Sensitivity/Resistance
- Trial name
- NCT03866343
- Testing
- Diet low or high in advanced glycation endproducts
- Where
- Netherlands
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stroke, Rehabilitation
Effects of Modified Constraint-Induced on Chronic Stroke Patients
In the present study, it was aimed to compare the proprioception training applied in addition to conventional treatment and Modified Constraint-Induced Movement Therapy treatment in patients with chronic strokes and to…
- Trial name
- NCT04873908
- Testing
- modified constraint-induced therapy, Proprioceptive Training, conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Acibadem University