Clinical trials: Functional Dyspepsia, open to volunteers
Functional Dyspepsia
Tradipitant for Functional Dyspepsia
To evaluate the effects of tradipitant relative to placebo on gastric motor functions, satiation, and postprandial symptoms in patients with functional dyspepsia.
- Trial name
- NCT05653310
- Testing
- Tradipitant
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Xiao Jing (Iris) Wang
Functional Dyspepsia
Budesonide as a Treatment for Functional Dyspepsia
This clinical study is being conducted to evaluate the investigational drug, Budesonide, for the treatment of functional dyspepsia.
- Trial name
- BuDy (NCT06841406)
- Testing
- budesonide, Mannitol
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction
Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional…
- Conditions
- Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS), Functional Dyspepsia
- Trial name
- PIPPI (NCT07319078)
- Testing
- Gut-directed hypnotherapy, Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Functional Dyspepsia, BIA
Bio-electrical Impedance Analysis in Patients With Functional Dyspepsia
The primary objective of this study is to compare the BIA parameters, including Phase Angle, Fat Free Mass and Fat Mass, between women with functional dyspepsia and healthy women.
- Conditions
- Functional Dyspepsia, BIA, Fat Free Mass, Fat Mass
- Trial name
- NCT07196735
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Functional Gastrointestinal Disorders
Exploring Novel Therapeutic Approaches for Disorders of Gut-Liver-Brain Interaction-H1/H2
Functional dyspepsia (FD) is associated with inflammatory responses caused by the release of histamine from eosinophils and mast cells, leading to increased intestinal mucosal permeability, which is a key pathogenic mechanism.
- Trial name
- NCT07857941
- Testing
- Famotidine, Levocetirizine, Fuyuan Gasmin
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies.
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders (FGIDs), Gastrointestinal and Digestive Disorder
- Trial name
- NCT07222943
- Testing
- Guided Imagery Therapy
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Baylor College of Medicine
Functional Dyspepsia, Irritable Bowel Syndrome With Diarrhea
Efficacy and Mechanistic Evaluation of Hewei Anchang Formula for Overlapping Gastrointestinal Symptoms in Patients With Coexisting Functional Dyspepsia and Diarrhea-Predominant Irritable Bowel Syndrome
1. To conduct a multicenter, randomized controlled trial across four hospitals to evaluate the efficacy of Hewei Anchang Formula in patients with overlapping gastrointestinal symptoms of functional dyspepsia (FD) and…
- Trial name
- NCT07715760
- Testing
- Hewei Anchang Formula Granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Functioanl Dyspepsia
Efficacy of Gut-Brain Neuromodulators for Functional Dyspepsia
The use of Neuromodulators is now recognized by international consensus as effective in improving Disorders of Gut-Brain Interaction (DGBIs).
- Trial name
- NCT06931223
- Testing
- Flupentixol-Melitracen + Lansoprazole, Lansoprazole
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Functional Dyspepsia
Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia
The goal of this clinical trial is to assess and compare the effect of amitriptyline and trifluoperazine in improving dyspeptic symptoms in patients with functional dyspepsia.
- Trial name
- NCT07008235
- Testing
- Tablet Amitriptyline 10 milligrams, Tablet Trifluoperazine 1 milligrams twice daily, Standard First-Line Therapy
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Md. Moktadirul Hoque Shuvo
Functional Dyspepsia
The Effects of STW 5-II on Duodenal Mucosa and Symptoms in Functional Dyspepsia
The goal of this clinical trial is to find out whether a herbal medicine called STW 5-II can help improve gut health and symptoms in adults recently diagnosed with functional dyspepsia (FD)-a condition that causes frequent…
- Trial name
- DESTINY (NCT07198243)
- Testing
- STW 5-II
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastroparesis
GI Neuromuscular Pathology Prospective Registry
In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future…
- Trial name
- NCT02165059
- Testing
- Surgical Full Thickness Biopsy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Functional Dysphonia
Assessment of the Efficacy of a Highly Standardized Ginger and Perilla Nutraceutical (Dispepril®) in Improving Gastric and Intestinal Symptoms in Patients With Functional Dyspepsia
This multicenter, prospective, randomized, controlled clinical trial aims to evaluate the efficacy of a nutraceutical treatment containing highly standardized extracts of ginger (Zingiber officinale) and perilla (Perilla…
- Trial name
- NCT07655219
- Testing
- Dispepril® (Pharmextracta S.p.A. Pontenure, Italy), Half-Dose PPI Plus Dispepril®, Full-Dose Proton Pump Inhibitor
- Where
- 4 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Functional Dyspepsia
Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia
The study aims at evaluating physiological and patient-reported outcomes for a dual intervention approach including a stimulation device and support therapy in patients with functional dyspepsia.
- Trial name
- CONVERGE (NCT06360900)
- Testing
- Sensory device, Skills Building, Health Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spaulding Rehabilitation Hospital
Functional Dyspepsia, Chronic Atrophic Gastritis (CAG)
Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms
Background: Dyspepsia is a common gastrointestinal complaint globally, affecting approximately 21.8% of the population. Among patients presenting with dyspeptic symptoms, over 80% are diagnosed with functional dyspepsia (FD)…
- Trial name
- NCT07250308
- Where
- China
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Postprandial Distress Syndrome, Functional Dyspepsia
Postprandial Distress Itopride Cohort Trial
Functional Dyspepsia (FD) is a common gastrointestinal disorder affecting about 7.2% of the population, characterized by gastroduodenal symptoms without an identifiable organic cause.
- Conditions
- Postprandial Distress Syndrome, Functional Dyspepsia, Epigastric Pain Syndrome
- Trial name
- PASSPORT (NCT07165301)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia
A Pilot Investigation of Pain Reprocessing Therapy for Functional Dyspepsia
The purpose of this research is to test whether pain processing therapy, a novel psychological intervention that emphasizes exposure-based techniques, can reduce digestive symptom severity and improve functioning in people with…
- Trial name
- NCT07838324
- Testing
- Pain Reprocessing Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Functional Dyspepsia, Insomnia
Auricular Stimulation for Functional Dyspepsia With Insomnia: Efficacy and Mechanisms
Functional dyspepsia (FD) is a chronic disorder of gut-brain interaction characterized by bothersome upper abdominal symptoms arising from the gastroduodenal region.
- Conditions
- Functional Dyspepsia, Insomnia, Brain and Nervous System
- Trial name
- NCT07442734
- Testing
- Auricular acupressure in concha area, Auricular acupressure in earlobe
- Where
- China
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Postprandial Distress Syndrome
Acotiamide vs Itopride in Postprandial Distress Syndrome
The goal of this study is to "To compare the efficacy and safety of Acotiamide versus Itopride in patient with post prandial distress syndrome type of functional dyspepsia"
- Trial name
- NCT07174297
- Testing
- Acotiamide
- Volunteers
- 152 people
- Sponsor
- Getz Pharma
Functional Dyspepsia
Evaluation of the Efficacy of Electroacupuncture in the Treatment of Functional Dyspepsia
Brief Summary Template for the Study: The goal of this clinical trial is to evaluate whether electroacupuncture can treat functional dyspepsia (FD) in adult participants aged 18 to 65 years, including both males and females, who…
- Trial name
- NCT06618911
- Testing
- 5 Hz electroacupuncture, 100 Hz electroacupuncture
- Where
- 4 sites in China
- Volunteers
- 180 people
- Sponsor
- Yi Liang