Clinical trials: Functional Abdominal Pain Disorders, open to volunteers
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD)
A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients
The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their gastrointestinal (GI) system.
- Conditions
- Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome, Abdominal Pain
- Trial name
- NCT07676136
- Testing
- Gut directed hypnotherapy via telephone intervention, Educational recording
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
Irritable Bowel Syndrome, Abdominal Pain
Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children
The goal of this clinical trial is to test efficacy of the REACH program in parents with irritable bowel syndrome (IBS) and their young children.
- Trial name
- REACH (NCT05730491)
- Testing
- Social Learning and Cognitive Behavioral Therapy (SLCBT), Attention Education Control
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Seattle Children's Hospital
IBS (Irritable Bowel Syndrome), Bloating
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating
This study is a randomized, double-blind, placebo-controlled, within-individual crossover trial designed to assess the impact of regular use of a consumer-grade FODMAP-targeting digestive enzyme blend (FODZYME®) on…
- Conditions
- IBS (Irritable Bowel Syndrome), Bloating, Abdominal Pain, Gut Health
- Trial name
- NCT07591584
- Testing
- FODMAP-targeting digestive enzyme blend
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kiwi Health Inc
Irritable Bowel Syndrome With Constipation
Home Transcutaneous Electrical Acustimulation (TEA)
This study will assess the efficacy of two active treatments with TEA and a chemical neuromodulator (escitalopram aka Lexapro) versus a sham comparator or control group on abdominal pain.
- Trial name
- Home-TEA (NCT05519683)
- Testing
- TEA, Lexapro
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome, Dyspepsia
Functional Digestive Disorders Observatory
Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating…
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Constipation, Faecal Incontinence
- Trial name
- OTFI (NCT04918329)
- Testing
- Observational study
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Rouen
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Abdominal Pain
ADAPTing CBT for Pediatric Functional Abdominal Pain in Primary Care
Many youth experience ongoing stomach pain that does not have a clear medical cause. These conditions, called functional abdominal pain disorders, are common and can last for years.
- Trial name
- ADAPT-PCP (NCT07526727)
- Testing
- Aim to Decrease Anxiety and Pain Treatment (ADAPT)
- Volunteers
- 15 people
- Sponsor
- Michigan State University
Abdominal Pain
Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain
The objectives of the study are to 1) Conduct telemetric biosignals (EDA, ECG, and EMG) recording in healthy controls and IBS participants experiencing cutaneous and visceral pain; and 2) Validate the OIME index as a biomarker…
- Trial name
- OIME (NCT06381921)
- Testing
- IBS-PPSM intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction
Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional…
- Conditions
- Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS), Functional Dyspepsia
- Trial name
- PIPPI (NCT07319078)
- Testing
- Gut-directed hypnotherapy, Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome
Effects of Aerobic Exercise and Pain Neuroscience Education in Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a chronic disorder of gut-brain interaction characterized by abdominal pain and changes in bowel habits.
- Trial name
- NCT07397533
- Testing
- Exercise, Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Istinye University
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies.
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders (FGIDs), Gastrointestinal and Digestive Disorder
- Trial name
- NCT07222943
- Testing
- Guided Imagery Therapy
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Baylor College of Medicine
Irritable Bowel Syndrome (IBS)
The Role That Food and Bacteria Play in Generating Abdominal Pain
Irritable Bowel Syndrom (IBS) affects up to five percent of Canadians and has proven difficult to treat. Our research will explore how a type of dietary carbohydrate, called FODMAPS, contributes to chronic abdominal pain in…
- Trial name
- NCT07688044
- Testing
- FODMAP Challenge
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- David Reed
Constipation - Functional, Abdominal Pain (AP)
Co-Development and Validation of Colonic Symptom Pictograms for Young People
Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in…
- Conditions
- Constipation - Functional, Abdominal Pain (AP), Nausea and Vomitting, Bloating
- Trial name
- NCT07337343
- Testing
- Pictogram comprehension and validation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Irritable Bowel Syndrome
Psyllium in Pediatric IBS
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating…
- Trial name
- Psyllium (NCT06639984)
- Testing
- Psyllium (0.7 g/year of age per day), Psyllium (0.5 g/year of age per day), fructans
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Dr Bruno Chumpitazi, M.D.
Pregnancy Related, Pelvic Floor Disorders
Effects of Reformer Pilates in Pregnant Women
Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity…
- Conditions
- Pregnancy Related, Pelvic Floor Disorders, Pain, Back, Pain, Neck
- Trial name
- NCT06777771
- Testing
- Reformer pilates exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Chronic Pancreatitis, Chronic Pain
QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Trial name
- NCT03434392
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Anna Evans Phillips
Abdominal Pain
ADAPTing CBT for Pediatric Functional Abdominal Pain in Spain
Many youth experience ongoing stomach pain that does not have a clear medical cause. These conditions, called functional abdominal pain disorders, are common and can last for years.
- Trial name
- NCT07874867
- Testing
- Aim to Decrease Anxiety and Pain Treatment (ADAPT)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Michigan State University