Clinical trials: Function
Coronary Artery Disease, Hypercholesterolemia
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
The aim of this study is to determine, whether an intensified atorvastatin therapy can improve monocyte function in patients with coronary artery disease and hypercholesterolemia.
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Monocyte Function
- Trial name
- NCT00329069
- Testing
- atorvastatin (drug)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Obesity
Effect of High Intensity Aerobic & Resistance Interval Training on Body Composition, Visceral Adiposity and Myocardial Function in Overweight and Obese Adults
The obesity epidemic, predisposing to cardio-metabolic diseases, has increased two-folds over the last decade with a global alarming cost of obesity-associated illnesses, thus representing a grave peril for the survival of public…
- Trial name
- NCT04708873
- Testing
- High intensity interval training, Moderate Intensity Continuous Training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Foundation University Islamabad
Motor Control Retraining, Close Kinetic Chain Exercises
Motor Control Retraining vs Close Kinetic Chain Exercises for Pain, Function and Vastus Medialis Oblique Strength in Patients With Patellofemoral Pain Syndrome
This study compares two treatments - motor control retraining and close kinetic chain exercises - to improves the pain, VMO strength, knee function.
- Conditions
- Motor Control Retraining, Close Kinetic Chain Exercises, Patellofemoral Pain Syndrome
- Trial name
- MCR VS CKC (NCT07766083)
- Testing
- Motor Control Retraining, Close Kinetic Chain Exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Faisalabad
Telerehabilitation, Chair-based Yoga
The Effects of Telerehabilitation And Chair-based Yoga In The Elderly
The aim of the study is to investigate the effects of chair-based yoga with rehabilitation on quality of life is affected in elderly people.
- Conditions
- Telerehabilitation, Chair-based Yoga, Elderly People
- Trial name
- NCT05598554
- Testing
- Telerehabilitation, information
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sevval Kadriye Bakir
Migraine
Imaging the Migraine Brain Pre- and Post-Erenumab
Researchers are trying to determine if there is a difference between brain images of subjects that do respond to treatment with erenumab and subjects who do not respond to treatment with erenumab using Magnetic Resonance Imaging…
- Trial name
- NCT03773562
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome
Cerebral Physiology of NOWS
This study will use a new device to measure blood flow and oxygen levels in the brains of newborn infants who have had exposure to opioid medications in the womb, compared to newborns who have not had any exposure.
- Conditions
- Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome, Opioid Use Disorder, Intrauterine Exposure
- Trial name
- NIRS for NOWS (NCT07610746)
- Testing
- FD-NIRS and DCS
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hepatic Cancer, Hepatocellular Carcinoma
Preoperative 3D Magnetic Resonance Elastography for Predicting Surgical Risk in Patients Undergoing Hepatectomy
How to accurately and safely evaluate regional liver function before hepatectomy remains an important unsolved problem in the surgical management of hepatocellular carcinoma (HCC).
- Conditions
- Hepatic Cancer, Hepatocellular Carcinoma, Intrahepatic Cholangiocellular Carcinoma, Metastatic Hepatocellular Carcinoma
- Trial name
- NCT07704203
- Testing
- Three-Dimensional Magnetic Resonance Elastography
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Congenital Sucrase-isomaltase Deficiency (CSID)
Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS)
Congenital sucrose-isomaltase deficiency (CSID) is a rare, genetic disease in which mutations in the sucrose-isomaltase (SI) gene cause digestion problems of sucrose resulting in diarrhea and abdominal pain.
- Trial name
- CSID GPS (NCT01914003)
- Where
- 19 sites in United States
- Volunteers
- 53 people
- Sponsor
- QOL Medical, LLC
Parkinson Disease, Gait
Computer-based Cognitive Training for Parkinson Disease
Parkinson's Disease (PD) is a neurodegenerative, progressive illness. It is a multi-system disease that influences not only the motor but also the cognitive and autonomic systems.
- Trial name
- NCT01121627
- Testing
- Computerized cognitive training
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Clalit Health Services
Aerobic Performance, Respiratory Function
Integrating Halotherapy Into Preseason Training Improves Respiratory and Aerobic Performance in Elite Female Soccer Players
This randomized controlled trial aimed to investigate the effects of a 12-week halotherapy intervention on respiratory muscle strength, pulmonary function, aerobic capacity, and intermittent running performance in elite female…
- Conditions
- Aerobic Performance, Respiratory Function, Athletic Performance, Respiratory Muscle Strength
- Trial name
- NCT07406386
- Testing
- Halotherapy Group, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Hip Fracture, Elderly Patients
Hope Theory-Based Nursing Intervention After Hip Fracture Surgery
This is a randomized controlled trial to evaluate the effectiveness of a Snyder Hope Theory-based nursing intervention on elderly patients following hip fracture surgery.
- Conditions
- Hip Fracture, Elderly Patients, Postoperative Recovery, Nursing Interventions
- Trial name
- NCT07400770
- Testing
- Snyder Hope Theory-based Nursing Intervention, Standard Postoperative Care
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Institute of Orthopaedic Surgery, Taizhou No.3 People's Hospital
Spinal Cord Injuries, Stroke
Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
Transcutaneous electrical stimulation (tcES) of the spinal cord has shown great promise in restoring upper extremity function after spinal cord injury (SCI).
- Trial name
- NCT06596369
- Testing
- Transcutaneous spinal cord stimulation, Upper extremity rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Stroke, Facial Palsy
Exteroceptive Stimulation for Facial Palsy After Stroke
Stroke is a leading cause of long-term disability worldwide and frequently results in central facial palsy, which manifests as facial asymmetry, impaired muscle control, and reduced functional ability.
- Trial name
- ES-FP (NCT07568769)
- Testing
- Exteroceptive Stimulation, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
Gender Dysphoria
Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery
For genital gender affirming surgery, it remains unclear to what extent genital sensitivity might be expected and what the impact of this might be on sexual functioning.
- Trial name
- PROGAS (NCT04993469)
- Testing
- Semmes-Weinstein monofilament testing and questionnaires
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Irritable Bowel Syndrome
A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome
This study is being done to see if St. John's wort helps people with irritable bowel syndrome, otherwise known as "IBS". St. John's wort is a herbal supplement derived from the St. John's wort plant.
- Trial name
- NCT00587860
- Testing
- St. John's wort
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Mayo Clinic
Frail Elderly, Exercise Therapy
A Multi-component Intervention in Frail Community-dwelling Older People
This study evaluates if a multi-component intervention, respecting the characteristics of frail older person and increasing intensity and challenge of exercises according to frail older person capacity/evolution will induce…
- Conditions
- Frail Elderly, Exercise Therapy, Physical Therapy Techniques
- Trial name
- MIF (NCT02918682)
- Testing
- Exercise - FIRST PHASE, Exercise - SECOND PHASE, Exercise - FOURTH PHASE
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy
A Novel Smartphone Application for "Smart" Trials
The overarching goal is to develop a mHealth App that can use smartphone embedded sensors to objectively collect physical function data in healthy individuals in the context of daily life.
- Trial name
- NCT04052282
- Testing
- Mobile Health App
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Liver Failure
Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test
The purpose of this study is to investigate safety and efficacy of intravenously injected 0.4% 13-C-Methacetin solution for the determination of liver function with the LiMAx-test on patients with partial liver resection.
- Trial name
- NCT01785082
- Testing
- 13-C-Methacetin
- Where
- 4 sites in Germany
- Volunteers
- 149 people
- Sponsor
- Humedics GmbH
Atrial Fibrillation
Henagliflozin in Patients With Atrial Fibrillation
The HENA-AF trial will evaluate the effects of henagliflozin on cardiac structure, function, and biomarkers of HF in patients with AF.
- Trial name
- HENA-AF (NCT05252624)
- Testing
- Henagliflozin 5Mg Tab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Anzhen Hospital
Primary Hyperalgesia
Sensory Function After Wound Instillation of Capsaicin
The use of capsaicin as a potential analgesic drug for postoperative pain relies on the ability of capsaicin to induce membrane lysis of c-nerve fibers.
- Trial name
- NCT00583180
- Testing
- Capsaicin
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet