Clinical trials: Function
Activities of Daily Living, Postural Control
Effect of Callisthenic Training on Mobility and ADL Performance in Spastic Diplegic Cerebral Palsy Patients
Almost 2 to 3 out of every 1000 children have Cerebral palsy in Pakistan.Spastic type of CP is dominant about 75%, diplegia (40%) and hemiplegic are (35.5%).Spastic diplegics have tightness of lower limb more than upper…
- Conditions
- Activities of Daily Living, Postural Control, Spasticity, Mobility
- Trial name
- NCT06966076
- Testing
- calisthenic training, Conventional physical therapy group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Aortic Valve Disease, Prosthesis; Cardiac, Heart, Functional Disturbance as Result
Aortic Valve Replacement Above the Aortic Annulus (SA-AVR) With the Carpentier-Edwards Magna-Ease Bioprosthesis
Surgical valve replacement is commonly performed in patients with severe aortic valve disease. In small aortic annulus, implantation of bioprosthetic valves can be associated with limited functional capacity.
- Trial name
- SA-AVR (NCT03976817)
- Testing
- aortic valve replacement
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Haemophilia A, Haemophilia B
A Study of the Impact of Hemophilia and Its Treatment on Brain Development, Thinking and Behaviour in Children With Hemophilia
The Hemophilia Growth and Development Study (HGDS) nearly 25 years ago showed haemophilia and HIV impacted brain development, thinking, and behaviour in children and adolescents.
- Trial name
- eTHINK (NCT03660774)
- Testing
- No treatment given
- Where
- 22 sites in United States
- Volunteers
- 563 people
- Sponsor
- Novo Nordisk A/S
Obesity, Healthy
Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype
The purpose of this research is to study the effect of the study drug (a conjugated bile acid dietary supplement) or placebo on cell function, hormones and body weight.
- Trial name
- NCT05314374
- Testing
- Ileocolonic-release conjugated bile acid
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Stroke
Comparison of Tele-rehabilitation Versus In-clinic Rehabilitation for Upper Limb Motor Function Stroke Patients
To determine the effects of Tele-rehabilitation versus in-clinical rehabilitation for upper limb motor function and spasticity in chronic ischemic stroke patients.
- Trial name
- NCT05875818
- Testing
- In-clinic Rehabilitation, Tele-rehabilitation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Superior University
β-thalassemia, Transfusional Iron Overload
Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload
The primary purpose of this study is to evaluate the effect of deferasirox on renal hemodynamics by determining glomerular filtration rate (GFR), renal plasma flow (RPF) and filtration fraction (FF).
- Trial name
- NCT00560820
- Testing
- Deferasirox
- Where
- 3 sites in Italy
- Volunteers
- 11 people
- Sponsor
- Novartis Pharmaceuticals
Cognitive Decline
Investigate the Effect of Tart Montmorency Cherry Juice (Prunus Cerasus) on Cerebral Blood Flow and Cognitive Function
Scientific studies in humans suggest that diets high in fruit and vegetables may be able to improve some aspects of mental performance such as improving memory and reaction times.
- Trial name
- NCT02381860
- Testing
- 60mL tart Montmorency cherry juice
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Parkinson Disease
rTMS on Motor Function of Parkinson's Disease Patients With Different Phenotypes
In this study we wondered whether patients with different phenotypes of Parkinson's disease respond differently to the protocol of repetitive transcranial magnetic stimulation (rTMS) associated with physical therapy.
- Trial name
- NCT04116216
- Testing
- High frequency repetitive transcranial magnetic stimulation, Low frequency repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Neck Pain
In Chronic Neck Pain; Kinesiophobia, Neck Awareness Examination of Cognitive and Cognitive Functions at Different Levels of Functionality
Chronic neck pain is a common problem in our society. With the Neck Disability Index, we can classify the functional status of individuals with chronic neck pain as "no restriction, mildly limited, moderately limited, severely…
- Trial name
- NCT05692206
- Testing
- evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Mustafa Kemal University
Glaucoma, Glaucoma Eye
Augmented Macular Pigment-containing Nutraceutical and Central Visual Function
The purpose of this study is to prospectively analyze changes in macular pigment optical density and dermal carotenoid levels as they relate to visual field function in patients prescribed a macular pigment-containing medical…
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
- Trial name
- NCT04676126
- Testing
- Lumega-Z, Dorzolamide Hcl 2% Oph Soln
- Where
- United States
- Sponsor
- University of the Incarnate Word
Abdomen Hernia, Respiratory Complication
Virtual Reality on Pulmonary Function After Upper Abdominal Surgeries
After upper abdomen surgery, respiratory muscle dysfunction is well recognised. After laparotomy and even laparoscopy, maximum static inspiratory and expiratory pressures are lowered, and recovery can take several days.
- Trial name
- NCT06301126
- Testing
- Virtual reality, conventional physical therapy exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Stroke
Augmenting Cerebral Blood Flow in Acute Ischemic Stroke
The most common type of stroke is ischemic (lack of blood flow to the brain due to a clot blocking a blood vessel). Time is brain and an average of 1.9 million brain nerve cells per minute are destroyed in patients experiencing a…
- Trial name
- NCT06911385
- Testing
- Arm Remote Ischemic Conditioning plus Pneumatic Compression lower limb
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Healthy
Lubiprostone, Colonic Motility and Sensation
This study is being done to evaluate the effects of lubiprostone, a drug approved and used for constipation, on pattern of contractions of the colon and the colon's sensitivity to distension.
- Trial name
- NCT00953043
- Testing
- lubiprostone, Bowel preparation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Systemic Lupus Erythematosus, Muscle Pain
Laser Therapy for Patients With Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs.
- Conditions
- Systemic Lupus Erythematosus, Muscle Pain, Chewing Function
- Trial name
- NCT04453215
- Testing
- GaAlAs semiconductor diode laser device
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Dr. Merve Benli
Renal Insufficiency, Acute
Evaluation of the Renal Function in an Ultra-endurance Race.
During ultra endurance events, athletes experience extreme physical and mental demands, sometimes at the limits of the adaptive response to human physiology.
- Trial name
- INFERNAL (NCT03136315)
- Testing
- INFERNAL Intervention
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Prostate Carcinoma
GET FIT Prostate: A Randomized Controlled Exercise Trial
The GET FIT Prostate trial (Group Exercise Training for Fall prevention and functional Improvements during and after Treatment for Prostate cancer) is a single-blind, parallel group, randomized controlled trial comparing - 1) tai…
- Trial name
- NCT03741335
- Testing
- Resistance Training, Stretching, Tai Chi
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- OHSU Knight Cancer Institute
Hepatitis C, Chronic
Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)
The purpose of this study is to evaluate the pharmacokinetics (PK) and safety and tolerability of single-dose administration of IDX719 in participants with normal hepatic function and participants with varying degrees of hepatic…
- Trial name
- NCT01919125
- Testing
- IDX719
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Depression, Stress Disorders, Post-Traumatic
Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms
It is important to provide support and resources for the many post-9/11 Veterans with mental health symptoms and poor psychosocial functioning who do not engage in psychotherapy.
- Trial name
- NCT07202325
- Testing
- Resilience Training for Veterans (REST-V), Usual resources
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
Pregnancy, Cesarean Section
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Conditions
- Pregnancy, Cesarean Section, Uterine Rupture
- Trial name
- NCT00517140
- Testing
- Repeat Caesaen section, vaginal delivery
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Hospital Authority, Hong Kong
Healthy Ageing, Cognitive Decline
Fitness, Ageing, and Bilingualism (FAB): The Benefits of Regular Exercise and Bilingualism for Language Abilities in Healthy Ageing.
This project investigates the relative benefits of regular physical activity and bilingualism for ameliorating cognitive decline in healthy ageing, with a particular focus on language function.
- Conditions
- Healthy Ageing, Cognitive Decline, Cardiorespiratory Fitness
- Trial name
- FAB (NCT07443189)
- Testing
- Home-Based HIIT
- Where
- 2 sites in Norway, United Kingdom
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Agder