Clinical trials: Function
Breast Cancer
Breast Reconstruction and Body Map : Assessment by Functional MRI (REMASCO)
Breast reconstruction is an integral part of the management of patients with breast cancer and treated by total mastectomy. The aim of breast reconstruction is to get a satisfying aesthetic and functional result (sensitivity) and…
- Trial name
- REMASCO (NCT02553967)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Oscar Lambret
Levothyroxine, Cardiac Function
Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism
This study aims to evaluate the effect of the treatment with levothyroxine on cardiac function in children with subclinical hypothyroidism.
- Conditions
- Levothyroxine, Cardiac Function, Children, Subclinical Hypothyroidism
- Trial name
- NCT07393165
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Fibromyalgia
Combined Effects of Progressive Relaxation Exercises and Aquatic Therapy in Fibromyalgia.
Fibromyalgia, a chronic pain disorder, presents a significant challenge in healthcare due to its widespread musculoskeletal pain, tenderness, and a spectrum of associated symptoms.
- Trial name
- NCT06460636
- Testing
- progressive muscle relaxation therapy, aquatic therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Fragile X Syndrome
Optical Imaging as a Tool for Monitoring Brain Function in Fragile X Syndrome
The objective of this project is to explore the potential of functional near- infrared spectroscopy (fNIRS) as innovative functional biomarker for clinical trial readiness in Fragile X Syndrome (FXS) that is still without cure.
- Trial name
- NCT06293027
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Major Depressive Disorder, Bipolar Disorder
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
The purpose of this research is to measure brain activity in individuals with mood disorders and memory problems using a simple, safe, and noninvasive method called functional near-infrared spectroscopy (fNIRS).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
- Trial name
- NCT06897670
- Testing
- Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Healthy Volunteers
Healthy Lung Study- Development of 3T MRI Hardware and Software for 3He Gas Imaging of the Lung: Healthy Volunteer Development Study
Healthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
- Trial name
- NCT03169673
- Testing
- Hyperpolarized Helium 3 Magnetic Resonance Imaging
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Healthy Aging, Cognitive Decline
Cognitively Enriched Walking Program
Dementia currently affects more than 47 million people worldwide, its prevalence is forecasted to triple by 2050, and it has been reported to be one of the most costly disorders in Belgium.
- Conditions
- Healthy Aging, Cognitive Decline, Physical Inactivity
- Trial name
- NCT05500183
- Testing
- Cognitively enriched walking program, walking program
- Where
- 2 sites in Belgium
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Ghent
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
GBM, Depression
The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Testing the effect of providing an antidepressant and anxiety-type escitalopram for patients with glioblastoma on patient's quality of life including the effect of treatment on mood and cognition during treatment.Two subgroups…
- Trial name
- Cipralex&GBM (NCT02623231)
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Muscle Weakness, Critical Illness
Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients
The investigators hypothesize that by applying a validated algorithm to accomplish early mobilization in surgical intensive care unit (ICU) patients, these patients will achieve a higher level of mobility which translates to…
- Conditions
- Muscle Weakness, Critical Illness, Respiratory Insufficiency
- Trial name
- mSOMS (NCT01363102)
- Testing
- SOMS
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Duchenne Muscular Dystrophy
Investigation of the Effects of Functional Inspiratory Muscle Training Applied With Tele-Rehabilitation on Respiratory and Functional Parameters and Quality of Life in Children With Duchenne Muscular Dystrophy: Randomized Controlled Study
Dushenne muscular dystrophy (DMD), which is characterized by the deficiency of dystrophin protein, prevents the muscle from maintaining its normal activity, causing progressive damage to the heart, respiratory muscles and…
- Trial name
- NCT07172737
- Testing
- Respiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Katip Celebi University
Stroke
Comparative Effects of Dual Task and PNF on Balance ,Cognition and Motor Function in Chronic Stroke Patients .
The aim of this study is to compare the effect of dual tasking and proprioceptive neuromuscular facilitation on balance, cognition and motor function in chronic stroke patients. It will be randomized clinical trial.
- Trial name
- NCT05931172
- Testing
- Dual tasking, PNF(proprioceptive neuromuscular facilitation exercises)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Arthroplasty
Preoperative Pain, Function, and Activity for Total Hip and Knee Arthroplasty Patients
This study wish to show if the preoperative level of pain, function or activity for hip and knee arthroplasty patients has any predictive value of the time it takes to fulfill the well-defined discharge criteria.
- Trial name
- NCT01248039
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Hvidovre University Hospital
Vertigo
2-dimensional Versus 3-dimensional Virtual Reality Game Training in BPPV
Despite successful maneuver applications in the treatment of BPPV, complaints of balance problems and dizziness persist. Many studies supports the notion that virtual reality (VR) allowing visual-vestibular interaction with a…
- Trial name
- NCT05021939
- Testing
- 2-Dimensional Group, 3-Dimensional Group
- Where
- Cyprus
- Volunteers
- 42 people
- Sponsor
- Eastern Mediterranean University
Stroke
Motor Performance in Chronic Stroke Patients
This study will determine in stroke patients whether stimulation of the injured side of the brain combined with stimulation of the weak hand can temporarily improve motor function of the paralyzed hand.
- Trial name
- NCT00110175
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Heart Transplant
Prospective L-arginine Study
HYPOTHESIS The investigators primary hypothesis is that peripheral endothelial function and exercise tolerance will be abnormal in the population of young heart transplant patients at baseline, and that each will show a trend…
- Trial name
- NCT01485757
- Testing
- L-arginine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Aging, Athletic Injuries
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability.
- Conditions
- Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
- Trial name
- NCT05344001
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marquette University
Stroke
Cognitive-motor Exercise for Stroke Patients in Function, Cognition and Related Brain Changes.
The purpose of this study is to evaluate a cognitive-motor exercise on dual-task interference during dual-task ankle movement and the corresponding alterations of brain activity.
- Trial name
- COGMOTION (NCT06362512)
- Testing
- Dual-task training, Single-task training, Upper limb strengthening exercise
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The Hong Kong Polytechnic University
Hip Injuries, Acetabular Labral Tear
A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement
This study aims to address hip labral tears and compare arthroscopic labral repair versus debridement in non-athletic population aged 20 to 50 years old, including both sexes.
- Conditions
- Hip Injuries, Acetabular Labral Tear, Femoro Acetabular Impingement
- Trial name
- NCT06288867
- Testing
- Arthroscopic Labral Repair, Arthroscopic Labral Debridement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Hemodialysis Complication
Exercise on Mitochondrial Functions of Lymphocyte in Hemodialysis
To improve aerobic capacity, muscular function and health-related quality of life in patients with end-stage renal disease (ESRD), regular exercise is recommended.
- Trial name
- NCT06417307
- Testing
- Supervised exercise training, Control group
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital