Clinical trials: Frail Elderly
Poor Performance Status, Muscle Weakness
SR-WBV Training for Frail Elderly in the Skilling up Stage
This randomized controlled study aims to examine long term effects in the skilling up phase over 4 weeks on physical functional performance and strength of mechanical SR-WBV and dance therapy intervention in a frail elderly…
- Trial name
- NCT01704976
- Testing
- SR-WBV
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Frailty, Exercise
Effects of Acupunch Exercises on the Frail Older Adults in Long-Term Care Facilities
Frailty is a complex elderly problem and a precursor of functional degradation in elder adults. The aim of this study will to test the effects of acupunch exercises on the frail older adults in long-term care facilities.
- Trial name
- NCT04481438
- Testing
- Acupunch Exercises
- Where
- 10 sites in Taiwan
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Cancer, Head and Neck Neoplasms
Radiotherapy, Cetuximab, and Injections of TNFerade™ Biologic for Elderly or Frail Patients With Head and Neck Cancer
This study is looking at the safety and tolerability of TNFeradeä Biologic combined with conventional once daily radiation therapy in elderly or frail patients with new onset locally advanced head and neck tumors.
- Trial name
- NCT00496236
- Testing
- TNFerade biologic
- Where
- United States
- Sponsor
- GenVec
Frailty
Telehealth-Supported Discharge Programme for Frail Older Adults
This pilot clinical trial aims to evaluate the feasibility, acceptability, and preliminary effectiveness of a telehealth-supported discharge programme on physical and mental health outcomes, and healthcare utilization among…
- Trial name
- NCT07490847
- Testing
- Telehealth discharge support programme
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Frailty, Nursing Home Residents
The Effect on Function of Increasing Activity for Nursing Home Residents
As designs of existing outcome studies are disparate and do not always relate well to a Swedish context, the need for further studies is obvious.
- Trial name
- NCT00218842
- Testing
- Individualized exercise
- Where
- Norway
- Volunteers
- 125 people
- Sponsor
- Norwegian University of Science and Technology
Frail Elderly
Unsupervised Elastic Band Exercises Performed by Frail Elderly Hospitalized Patients Monitored by the Bandcizer
This feasibility study investigates if frail elderly and hospitalized patients are able to perform unsupervised elastic band exercises as a supplement to their usual supervised physiotherapy sessions and how much training they…
- Trial name
- NCT02702557
- Testing
- Elastic Band Exercises
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Aalborg University Hospital
Sedentary Behavior, Frail Elderly Syndrome
Effect of an Intervention on Health in Older Care Home Residents
Care home residents spent 79% of their time being sedentary. Reduced physical activity and lack of mental stimulation causes general weakness and frailty in older adults that can result in increased healthcare needs.
- Conditions
- Sedentary Behavior, Frail Elderly Syndrome, Frailty, Lifestyle, Sedentary
- Trial name
- NCT04659694
- Testing
- Wellness programme provided by Oomph! Wellness company
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bournemouth University
Fraility, COPD (Chronic Obstructive Pulmonary Disease)
Respiratory Exercises in Frail Elderly COPD Patients
Purpose: This study evaluated the impact of a structured intervention on frailty, lung function, physical capacity, and dyspnea in elderly COPD patients.
- Conditions
- Fraility, COPD (Chronic Obstructive Pulmonary Disease), Older Adults (65 Years and Older)
- Trial name
- NCT07472530
- Testing
- breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Deprescriptions, Polypharmacy
Optimising Medication With Focus on Deprescribing in Frail Older People With Multidose Drug Dispensing Systems
Overuse is common in frail older people with polypharmacy, especially in frail older users of multidose drug dispensing (MDD) systems.
- Conditions
- Deprescriptions, Polypharmacy, Primary Health Care, Community Pharmacy Services
- Trial name
- NCT05609981
- Testing
- Clinical medication review focused on deprescribing
- Where
- Netherlands
- Volunteers
- 318 people
- Sponsor
- SIR Institute for Pharmacy Practice and Policy
Malnutrition; Protein, Frail Elderly Syndrome
Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty
The aim of the study is to determine whether the optimisation of the preoperative nutritional status affects the course of the perioperative period in patients with frailty.
- Trial name
- NCT05118165
- Testing
- Dietary supplement with protein
- Volunteers
- 176 people
- Sponsor
- Lithuanian University of Health Sciences
Delirium, Hip Fracture
Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality.
- Trial name
- RASAPOD (NCT02689388)
- Testing
- Femoral Nerve Block
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Auckland City Hospital
Aging, Frail Elderly Syndrome
HMB Supplementation in Addition to Multicomponent Exercise in Old Adults
Evidence supports the fact that multicomponent exercise and β-hydroxy-β-methylbutyrate (HMB) supplementation are, separately, effective in improving old adult's health and palliate functional metabolic diseases in the elderly.
- Conditions
- Aging, Frail Elderly Syndrome, Physical Activity
- Trial name
- HEAL (NCT03827499)
- Testing
- HMB dietary supplementation, Multicomponent physical exercise program
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Frailty at Older Adults, Mild Cognitive Impairment
A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults
The goal of this clinical trial is to explore the effects of intermittent theta burst stimulation (iTBS) primed with theta burst stimulation (cTBS), on top of aerobic exercise, on cognitive function, mobility, and brain activity…
- Trial name
- TMS MRI TBS (NCT07497334)
- Testing
- Theta burst stimulation, Aerobic exercise
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- The Hong Kong Polytechnic University
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
- Trial name
- ZEST II (NCT02589600)
- Testing
- Zoledronic acid, vitamin D, calcium
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Susan L. Greenspan
Colon Cancer
PrehabPal: A Digital Tool to Help Older Adults Prepare for Cancer Surgery
This is a multi-center, randomized trial investigating the use of PrehabPal web app versus a written surgery prehabilitation instructions among individuals aged 65 years and older preparing for colon cancer surgery.
- Trial name
- NCT05520866
- Testing
- PrehabPal
- Where
- 3 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Frail Elderly Syndrome, Sarcopenia
Multidimensional Intervention in Pre-frail Patients Older Than 70 Years
Aging represents a huge advance in society and a health and social challenge. Spain has one of the highest life expectancies in the world, but other countries with the same demographic characteristics are ahead of us in quality…
- Trial name
- NCT04574271
- Testing
- Intensive dietary advice and exercise prescription, Usual dietary advice and exercise prescription
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Endocrinology and Clinical Nutrition Research Center, Spain